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AN SVAD ALGORITHM BASED ON FNNKD METHOD
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作者 chendong ZhangYan 《Journal of Electronics(China)》 2002年第3期280-288,共9页
The capacity of mobile communication system is improved by using Voice Activity Detection (VAD) technology. In this letter, a novel VAD algorithm, SVAD algorithm based on Fuzzy Neural Network Knowledge Discovery (FNNK... The capacity of mobile communication system is improved by using Voice Activity Detection (VAD) technology. In this letter, a novel VAD algorithm, SVAD algorithm based on Fuzzy Neural Network Knowledge Discovery (FNNKD) method is proposed. The performance of SVAD algorithm is discussed and compared with traditional algorithm recommended by ITU G.729B in different situations. The simulation results show that the SVAD algorithm performs better. 展开更多
关键词 FNNKD VAD Adaptive Multi-Rate (AMR) Heuristic Gradient Learning Algorithm (HGLA)
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肝动脉化疗栓塞联合索拉菲尼治疗肝细胞肝癌的疗效及其预后分析 被引量:15
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作者 王卫东 侯思楠 +6 位作者 陈栋 江雄鹰 倪嘉延 陈耀庭 孙宏亮 骆江红 许林锋 《中华肝脏病杂志》 CAS CSCD 北大核心 2018年第9期690-693,共4页
肝癌发病隐匿、恶性程度高、进展速度快,大多数肝癌患者初诊时已处于肿瘤发展的中晚期阶段,肝动脉化疗栓塞(TACE)是目前中晚期肝癌的首选治疗。既往随机对照试验荟萃分析显示TACE可明显提高患者短期生存率。然而栓塞引起的肿瘤缺血... 肝癌发病隐匿、恶性程度高、进展速度快,大多数肝癌患者初诊时已处于肿瘤发展的中晚期阶段,肝动脉化疗栓塞(TACE)是目前中晚期肝癌的首选治疗。既往随机对照试验荟萃分析显示TACE可明显提高患者短期生存率。然而栓塞引起的肿瘤缺血缺氧会反馈刺激血管内皮细胞生长因子(VEGF)水平的升高,进一步刺激肿瘤新生血管形成而导致肿瘤复发转移;这些局限致其远期临床疗效仍不理想。 展开更多
关键词 肝细胞 预后 回归分析 肝动脉化疗栓塞术 索拉菲尼
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MAP Kinases in Immune Responses 被引量:19
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作者 YongliangZhang chendong 《Cellular & Molecular Immunology》 SCIE CAS CSCD 2005年第1期20-27,共8页
MAP kinases are evolutionarily conserved signaling regulators from budding yeast to mammals and play essential roles in both innate and adaptive immune responses.There are three main families of MAPKs in mammals.Each ... MAP kinases are evolutionarily conserved signaling regulators from budding yeast to mammals and play essential roles in both innate and adaptive immune responses.There are three main families of MAPKs in mammals.Each of them has its own activators,inactivators,substrates and scaffolds,which altogether form a fine signaling network in response to different extracellular or intracellular stimulation.In this review,we summarize recent advances in understanding of the regulation of MAP kinases and the roles of MAP kinases in innate and adaptive immune responses.Cellular & Molecular Immunology.2005;2(1):20-27. 展开更多
关键词 MAP kinase MAP kinase phosphatase scaffold protein innate immune response adaptive immune response
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Biological effect of velvet antler polypeptides on neural stem cells from embryonic rat brain 被引量:14
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作者 LULai-jin CHENLei +3 位作者 MENGXiao-ting YANGFan ZHANGZhi-xin chendong 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第1期38-42,共5页
Background Velvet antler polypeptides (VAPs), which are derived from the antler velvets, have been reported to maintain survival and promote growth and differentiation of neural cells and, especially the development ... Background Velvet antler polypeptides (VAPs), which are derived from the antler velvets, have been reported to maintain survival and promote growth and differentiation of neural cells and, especially the development of neural tissues This study was designed to explore the influence of VAPs on neural stem cells in vitro derived from embryonic rat brain Methods Neural stem cells derived from E12 14 rat brain were isolated, cultured, and expanded for 7 days until neural stem cell aggregations and neurospheres were generated The neurospheres were cultured under the condition of different concentration of VAPs followed by immunocytochemistry to detect the differentiation of neural stem cells Results VAPs could remarkablely promote differentiation of neural stem cells and most neural stem cells were induced to differentiate towards the direction of neurons under certain concentration of VAPs Conclusion Neural stem cells can be successfully induced into neurons by VAPs in vitro , which could provide a basis for regeneration of the nervous system 展开更多
关键词 neural stem cell · velvet antler polypeptides · differentiation · neuron
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