Background It is welt known that increased cumulative ventricular pacing proportion （CumVP%） is one of the most important causes for adverse cardiovascular events. Therefore, how to reduce CumVP% has been a treatmen...Background It is welt known that increased cumulative ventricular pacing proportion （CumVP%） is one of the most important causes for adverse cardiovascular events. Therefore, how to reduce CumVP% has been a treatment issue in recent years. This study aimed to investigate the effects of different pacing algorithms on CumVP% in patients with pacemakers. Methods Pacemakers with three pacing algorithms, i.e., conventional dual chamber rate adaptive pacing （DDDR）, search atrioventricular conduction plus （SAV＋） and managed ventricular pacing （MVP）, were implanted in 42 patients including 41 with bradycardia arrhythmias and one with ventricular tachycardia. Pacemakers were programmed to work in conventional DDDR, SAV＋ and MVP during the follow-up periods of the first, the second and the third month. In each pacing algorithm, the time percentages of four pacing and sense status including atrial sense-ventricular sense （AS-VS）, atrial sense-ventricular pacing （AS-VP）, atrial pacing-ventricular sense （AP-VS） and atrial pacing-ventricular pacing （AP-VP） were calculated. Cumulative ventricular pacing proportions were compared in the three pacing algorithms in the first, the second and the third month postoperatively. Results In the DDDR algorithm AS-VS, AS-VP, AP-VS and AP-VP were 2.4%, 52.3%, 2.5% and 42.8% respectively, while in SAV＋ they were 19.3%, 34.9%, 33.9% and 12.0%, in MVP they were 38.9%, 13.2%, 41.6% and 6.4%. In the above the DDDR, SAV＋ and MVP algorithms, cumulative ventricular pacing proportions were 95.1%, 46.9% and 19.6%, respectively （P〈0.05） and the percentages of CumVP% 〈40% in patients were 0, 23.8% and 95.2.0% （P〈0.05）. Conclusions Compared with the conventional DDDR algorithm, both SAY＋ and MVP significantly reduced the CumVP%, especially the MVP algorithm. Patients may benefit from MVP algorithm due to reduced CumVP%.展开更多
文摘Background It is welt known that increased cumulative ventricular pacing proportion （CumVP%） is one of the most important causes for adverse cardiovascular events. Therefore, how to reduce CumVP% has been a treatment issue in recent years. This study aimed to investigate the effects of different pacing algorithms on CumVP% in patients with pacemakers. Methods Pacemakers with three pacing algorithms, i.e., conventional dual chamber rate adaptive pacing （DDDR）, search atrioventricular conduction plus （SAV＋） and managed ventricular pacing （MVP）, were implanted in 42 patients including 41 with bradycardia arrhythmias and one with ventricular tachycardia. Pacemakers were programmed to work in conventional DDDR, SAV＋ and MVP during the follow-up periods of the first, the second and the third month. In each pacing algorithm, the time percentages of four pacing and sense status including atrial sense-ventricular sense （AS-VS）, atrial sense-ventricular pacing （AS-VP）, atrial pacing-ventricular sense （AP-VS） and atrial pacing-ventricular pacing （AP-VP） were calculated. Cumulative ventricular pacing proportions were compared in the three pacing algorithms in the first, the second and the third month postoperatively. Results In the DDDR algorithm AS-VS, AS-VP, AP-VS and AP-VP were 2.4%, 52.3%, 2.5% and 42.8% respectively, while in SAV＋ they were 19.3%, 34.9%, 33.9% and 12.0%, in MVP they were 38.9%, 13.2%, 41.6% and 6.4%. In the above the DDDR, SAV＋ and MVP algorithms, cumulative ventricular pacing proportions were 95.1%, 46.9% and 19.6%, respectively （P〈0.05） and the percentages of CumVP% 〈40% in patients were 0, 23.8% and 95.2.0% （P〈0.05）. Conclusions Compared with the conventional DDDR algorithm, both SAY＋ and MVP significantly reduced the CumVP%, especially the MVP algorithm. Patients may benefit from MVP algorithm due to reduced CumVP%.
