Oligodendrocytes in central nervous system diseases:the effect of cytokine regulation

Cytokines including tumor necrosis factor, interleukins, interferons, and chemokines are abundantly produced in various diseases. As pleiotropic factors, cytokines are involved in nearly every aspect of cellular functions such as migration, survival, proliferation, and differentiation. Oligodendrocytes are the myelin-forming cells in the central nervous system and play critical roles in the conduction of action potentials, supply of metabolic components for axons, and other functions. Emerging evidence suggests that both oligodendrocytes and oligodendrocyte precursor cells are vulnerable to cytokines released under pathological conditions. This review mainly summarizes the effects of cytokines on oligodendrocyte lineage cells in central nervous system diseases. A comprehensive understanding of the effects of cytokines on oligodendrocyte lineage cells contributes to our understanding of central nervous system diseases and offers insights into treatment strategies.

油水分离膜表面结构可控合成及性能研究

石油开采过程中会产生大量的油水混合物,每天生产生活中也会产生大量含油废水,如何处理这些油水混合物,是环境保护和可持续发展的重大需求。针对含油量较高的油水混合物,本工作制备了疏水-超亲油分离膜。以机械性能较好的泡沫镍为过滤基体,采用电沉积方法,在泡沫镍表面沉积铜颗粒,构筑亲油疏水表面。研究了沉积电位和沉积时间对表面结构的影响,并测试了分离膜表面结构、表面粗糙度及水滴在膜表面的接触角,并对所制备的分离膜进行油水分离性能测试和多次循环的稳定性测试。结果表明,所制备的分离膜具有良好的循环分离性能,对于油水混合物循环十次后分离效率仍在90%以上。本研究为高效油水分离膜材料开发提供了新思路,并拓展了电化学表面改性的应用领域。