Epigenetics refers to how chromatin-associated factors and reversible chromatin modifications maintain DNA-based programs by regulating the chromatin structure(Strahl and Allis,2000).In recent years,genome sequencing ...Epigenetics refers to how chromatin-associated factors and reversible chromatin modifications maintain DNA-based programs by regulating the chromatin structure(Strahl and Allis,2000).In recent years,genome sequencing studies of cancer have shown that genes encoding epigenetic factors are commonly mutated in cancer(Garraway and Lander,2013).Dys regulated,or mutant.展开更多
基金supported by the National Natural Science Foundation of China(81672771 and 81871867 to C.X.)the Ministry of Science and Technology of the People’s Republic of China(2017YFA0504102 to D.P.)+1 种基金Tianjin Municipal Special Program of Talents Development for Excellent Youth ScholarsThe Chair of this National Key Research and Development Project(2017YFA0504102)is Duanqing Pei,and the corresponding author of this artical,Chenghao Xuan,is one of the members of the project.
文摘Epigenetics refers to how chromatin-associated factors and reversible chromatin modifications maintain DNA-based programs by regulating the chromatin structure(Strahl and Allis,2000).In recent years,genome sequencing studies of cancer have shown that genes encoding epigenetic factors are commonly mutated in cancer(Garraway and Lander,2013).Dys regulated,or mutant.
