A radical-induced 1,2-α-boryl migration through radical polar crossover reactions has been described.In this work,in situ formed vinyldiboron“ate”complexes from alkenyl Grignard reagent and diborylalkanes react wit...A radical-induced 1,2-α-boryl migration through radical polar crossover reactions has been described.In this work,in situ formed vinyldiboron“ate”complexes from alkenyl Grignard reagent and diborylalkanes react with commercial radical precursors under light initiation.This three-component process enables diborylation of alkene.This protocol features high atom economy,a broad substrate scope as well as good functional group toleration with mild conditions.展开更多
Main observation and conclusion A method for photoinduced NaI-promoted radical borylation of aliphatic halides and pseudohalides with bis(catecholato)diboron(B_(2)cat_(2))as the boron source is introduced.The borylati...Main observation and conclusion A method for photoinduced NaI-promoted radical borylation of aliphatic halides and pseudohalides with bis(catecholato)diboron(B_(2)cat_(2))as the boron source is introduced.The borylation reaction is operationally simple and shows high functional group tolerance and broad substrate scope.Preliminary mechanistic studies suggest that the reaction proceeds through S_(N)2-based radical-generation strategy.展开更多
基金Financial supports from the National Natural Science Foundation of China(Nos.21772046,2193103,22001038)are gratefully acknowledged.
文摘A radical-induced 1,2-α-boryl migration through radical polar crossover reactions has been described.In this work,in situ formed vinyldiboron“ate”complexes from alkenyl Grignard reagent and diborylalkanes react with commercial radical precursors under light initiation.This three-component process enables diborylation of alkene.This protocol features high atom economy,a broad substrate scope as well as good functional group toleration with mild conditions.
基金Financial support from the National Natural Science Foundation of China(Nos.21772046,2193103,22001038)are gratefully acknowledged.
文摘Main observation and conclusion A method for photoinduced NaI-promoted radical borylation of aliphatic halides and pseudohalides with bis(catecholato)diboron(B_(2)cat_(2))as the boron source is introduced.The borylation reaction is operationally simple and shows high functional group tolerance and broad substrate scope.Preliminary mechanistic studies suggest that the reaction proceeds through S_(N)2-based radical-generation strategy.
