To the editor:Paclitaxel is one of the most widely used chemotherapy drugs for treating several types of cancer,including lung,breast,and cervical cancers^(1,2).Clinical application of paclitaxel is closely associated...To the editor:Paclitaxel is one of the most widely used chemotherapy drugs for treating several types of cancer,including lung,breast,and cervical cancers^(1,2).Clinical application of paclitaxel is closely associated with a serious adverse effect known as chemotherapy-induced peripheral neuropathy(CIPN),which affects 44%-98%of patients treated with paclitaxel,causing symptoms such as loss of sensation,burning or tingling sensations,abnormal pain,and difficulties in performing daily activities^(3).It is worth noting that the pathogenesis of CIPN remains unclear,and currently there is a lack of effective treatment strategies.展开更多
基金supported by grants from National Natural Science Foundation of China(Grant Nos.82173666 and 81971065)Shenzhen science and technology research and development funds(Grant Nos.JCYJ20210324094612035 and JCYJ20190808154603578,China).
文摘To the editor:Paclitaxel is one of the most widely used chemotherapy drugs for treating several types of cancer,including lung,breast,and cervical cancers^(1,2).Clinical application of paclitaxel is closely associated with a serious adverse effect known as chemotherapy-induced peripheral neuropathy(CIPN),which affects 44%-98%of patients treated with paclitaxel,causing symptoms such as loss of sensation,burning or tingling sensations,abnormal pain,and difficulties in performing daily activities^(3).It is worth noting that the pathogenesis of CIPN remains unclear,and currently there is a lack of effective treatment strategies.
