To improve the efficacy of traditional chemotherapy and radiotherapy and reduce their serious side effects,further efforts need to be exerted to identify better cancer therapeutic options that are effective,affordable...To improve the efficacy of traditional chemotherapy and radiotherapy and reduce their serious side effects,further efforts need to be exerted to identify better cancer therapeutic options that are effective,affordable,and acceptable to patients.In this study,a novel theranostic agent was produced to perform synergetic cancer immunotherapy and phototherapy.The theranostic agent,named natural killer(NK)cells carrying indocyanine green loaded liposomes was synthesized NK cells with ICG nanoparticles to serve as the agent for a newly-established cancer treatment.It is expected that the developed synergistic therapy can pave a new avenue for improved efficacy of cancer theranostics.展开更多
基金This work was supported by the Science and Technology Development Fund of Macao(FDCT/131/2016/A3,FDCT/0015/2018/A1,FDCT/0011/2018/A1)the Guangzhou Science and Technology Program(No.201807010004)+1 种基金Start-up Research Grant(SRG2016-00082-FHS)the intramural research program of Faculty of Health Sciences,University of Macao,and National Natural Science Foundation of China(No.31440041).First,second,third,fifth and sixth authors contributed equally to this work.
文摘To improve the efficacy of traditional chemotherapy and radiotherapy and reduce their serious side effects,further efforts need to be exerted to identify better cancer therapeutic options that are effective,affordable,and acceptable to patients.In this study,a novel theranostic agent was produced to perform synergetic cancer immunotherapy and phototherapy.The theranostic agent,named natural killer(NK)cells carrying indocyanine green loaded liposomes was synthesized NK cells with ICG nanoparticles to serve as the agent for a newly-established cancer treatment.It is expected that the developed synergistic therapy can pave a new avenue for improved efficacy of cancer theranostics.
