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Effects of oxygen enriched tent by a new oxygen concentration machine on blood oxygen saturation and heart rate in tibet 被引量:2
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作者 Guang-Hao Shen Kun Wang +5 位作者 Li-Hua Lu Kang-Ning Xie Qiao-Ling Xu Xiao-Ming Wu chi tang Er-Ping Luo 《Journal of Biomedical Science and Engineering》 2011年第2期130-135,共6页
Many people who live in the low altitude areas are often suffered from hypoxia when they entered the high plateau. This problem may seriously influence the physical and mental state and work efficacy for the travelers... Many people who live in the low altitude areas are often suffered from hypoxia when they entered the high plateau. This problem may seriously influence the physical and mental state and work efficacy for the travelers and workers. Oxygen enrichment of a small space air at high altitude is considered as a simple way to provide lowlanders enriched oxygen for sleeping and resting, improving work efficiency, so we developed an oxygen concentration machine based on the technology of oxygen enrichment membrane. This paper tested 8 healthy male lowlanders (age 21.63±1.77 yr) who have never exposed to plateau performed an incremental exercise on cycle ergometer at sea-level in order to be used as sea-level controls. Two days later, the same subjects were taken to Lhasa (3700 m) by air and exposed to the plateau, performed the same exercise as they did at sea-level. The next day, all subjects were asked to enter the experimental tent which was enriched with oxygen (higher than 24%) by the oxygen concentration machine and sleep for 10 hours at night, then exposed to plateau and performed the same exercise twice at different time (2 hours and 10 hours after oxygen enrichment). During the tests, subjects must cycled continuously at 60 rpm beginning with a 3 min exercise intensity of 0 W followed by incremental increases of 25 W every 3 min until 150 W, pulse oxygen saturation (SpO2) and heart rate (HR) were recorded. After sleeping in an oxygen enrichment of tent air, 2 hours later, the subjects’ load capacity had no difference compared with control group, but significant difference than before (higher SpO2 and lower HR), which indicated that oxygen concentration machine is effective in increasing the oxygen concentration of the air for the tent and sleeping in the oxygen enrichment tent for l0 h might be effective in improving exercise performance during high-altitude hypoxia. At the same time, 10 hours later, when work-load exceeded 125 W, the same effects were also found. The results indicated the effects of oxygen enrichment of tent air could last a certain period of time. 展开更多
关键词 HYPOXIA OXYGEN Concentration MACHINE OXYGEN ENRICHMENT Membrane High PLATEAU OXYGEN ENRICHMENT
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融合迭代式关系图匹配和属性语义嵌入的实体对齐方法
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作者 迟棠 车超 《计算机科学》 CSCD 北大核心 2023年第S02期69-74,共6页
实体对齐是知识融合中的关键步骤,用于解决多源知识图谱中实体冗余、指代不明等问题。目前,大多数的实体对齐方法主要依赖于邻域网络,而忽略了关系间的连通以及属性信息,导致模型无法捕捉到复杂关系,额外信息也没有被充分利用。针对上... 实体对齐是知识融合中的关键步骤,用于解决多源知识图谱中实体冗余、指代不明等问题。目前,大多数的实体对齐方法主要依赖于邻域网络,而忽略了关系间的连通以及属性信息,导致模型无法捕捉到复杂关系,额外信息也没有被充分利用。针对上述问题,提出一种迭代式关系图匹配和属性语义嵌入的实体对齐方法,将〈头实体,关系,尾实体〉进行转置,生成〈头关系,实体,尾关系〉构建,与实体图相对应的关系图,接着利用注意力机制编码实体和关系表示,二者通过相互迭代,能够更好地表示实体,再融合属性表示最终判定两个实体是否对齐。实验结果表明,本模型在DBP15K 3个跨语言数据集中显著优于其他6种方法,相比于最好方法Hit@1指标提升了4%,证明了关系匹配和属性语义的有效性。 展开更多
关键词 知识图谱 实体对齐 图神经网络 关系匹配 属性语义
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纤维素和甲醇共催化热解制备对二甲苯(英文) 被引量:1
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作者 唐驰 朱丽娟 +1 位作者 范明慧 李全新 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2018年第6期843-850,734,共9页
本文对纤维素和甲醇在不同金属氧化物改性的ZSM5催化剂作用下共催化快速热解实现一步制备可再生对二甲苯的过程进行了研究.结果表明,镧改性的ZSM5催化剂是生产生物基对二甲苯的有效催化剂.对二甲苯的选择性和产率主要由催化剂酸性、反... 本文对纤维素和甲醇在不同金属氧化物改性的ZSM5催化剂作用下共催化快速热解实现一步制备可再生对二甲苯的过程进行了研究.结果表明,镧改性的ZSM5催化剂是生产生物基对二甲苯的有效催化剂.对二甲苯的选择性和产率主要由催化剂酸性、反应温度和甲醇含量决定.在20%La2O3-ZSM5(80)催化剂作用下,纤维素与33wt%甲醇共催化快速热解获得对二甲苯的最高收率和对二甲苯/二甲苯的最高比率分别为14.5C-mol%和86.8%.本文详细研究了催化热解过程中催化剂的失活,基于产物的分析和催化剂的表征提出了由纤维素制备对二甲苯的可能反应途径. 展开更多
关键词 纤维素 对二甲苯 催化快速热解 镧改性的ZSM5
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Comparison of Clinical Thinking Ability in Nursing Students of Different Grades 被引量:3
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作者 Jun-Yan Song Xiu-Li Zhu +4 位作者 Cui-Ping Liu Xiu-Xin Miao Xue-Zhu Lin Hui-Li Guo chi tang 《Chinese Nursing Research》 CAS 2014年第1期30-35,共6页
Objective: This study investigated and compared the clinical thinking ability of undergraduate nursing students of different grades, and searched for influencing factors of clinical thinking ability of nursing underg... Objective: This study investigated and compared the clinical thinking ability of undergraduate nursing students of different grades, and searched for influencing factors of clinical thinking ability of nursing undergraduate students. Methods: The convenience sampling method was used to select the Subject of the study. In total, 180 third-year, fourth-year, and fifth-year nursing undergraduate students were enrolled in this study. A self-designed scale of clinical thinking ability was used to collect the data. SPSS17.0 was used to analyze the data. Results: The average scores of clinical thinking ability of undergraduate nursing students were 68.14±9.13. In addition, 71.1% of the students have a higher level of clinical thinking ability, and only 7.2% of the students have the best level. The ANOVA test showed that the fourth-year students had the highest scores(72.96±8.64), and the third-year students had the lowest scores(62.35±8.09), which indicated a significant difference in the scores of the three groups( F= 26. 79, P〈0.05). Multiple linear regression analysis indicated that the frequency of academic activities and the frequency of department rounds were significantly correlated to clinical thinking ability(P〈0.05). Conclusion: We must pay attention to the changes and influencing factors of clinical thinking ability of nursing undergraduate students. Thus, traditional teaching methods need to evolve and be revised to host the capacity of clinical practice most effectively and, eventually, promote the development of clinical thinking ability of nursing undergraduate students. 展开更多
关键词 Nursing undergraduate students Clinical thinking ability Nursing education Influence factors
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连续性肾脏替代疗法治疗ICU患者的临床疗效研究
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作者 池塘 候亮 《中国继续医学教育》 2021年第28期127-130,共4页
目的深入分析连续性肾脏替代疗法治疗ICU患者的临床疗效。方法医院对80例ICU患者的临床资料进行总结,并依据随机数表法将患者分为对照组和试验组,各40例,两组患者的入院时间均在2018年4月—2020年6月期间。对照组在试验过程中采用传统... 目的深入分析连续性肾脏替代疗法治疗ICU患者的临床疗效。方法医院对80例ICU患者的临床资料进行总结,并依据随机数表法将患者分为对照组和试验组,各40例,两组患者的入院时间均在2018年4月—2020年6月期间。对照组在试验过程中采用传统治疗方式,而试验组采用连续性肾脏替代疗法对患者实施干预措施,并通过相关数据将两组患者肾功能指标以及治疗效果进行对比分析。结果试验组在接受连续性肾脏替代疗法后肾功能指标均低于对照组,同时试验组患者治疗后临床效果显著高对照组,组间数据具备明显对比分析意义,差异具有统计学意义,(P<0.05)。结论将连续性肾脏替代疗法应用到治疗ICU患者中能够改善患者的肾脏功能,有效提高临床治疗效果,对延缓患者的生存时间、提升患者的生活质量具有重要意义。 展开更多
关键词 肾脏替代疗法 肾功能 器官衰竭 治疗 生活质量 临床效果
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睡眠碎片化对大鼠血管性认知障碍的影响及其与中枢炎症和氧化应激的关系 被引量:6
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作者 姚鹏 陈勇 +3 位作者 池塘 王文莉 沈威 徐文浩 《中华麻醉学杂志》 CAS CSCD 北大核心 2020年第2期168-172,共5页
目的评价睡眠碎片化对大鼠血管性认知障碍的影响及其中枢炎症和氧化应激的关系。方法雄性SD大鼠48只,8~10周龄,体重210~240 g,采用随机数字表法分为4组(n=12):假手术组(Sham组)、假手术+睡眠碎片化组(Sham+SF组)、血管性认知障碍组(VCI... 目的评价睡眠碎片化对大鼠血管性认知障碍的影响及其中枢炎症和氧化应激的关系。方法雄性SD大鼠48只,8~10周龄,体重210~240 g,采用随机数字表法分为4组(n=12):假手术组(Sham组)、假手术+睡眠碎片化组(Sham+SF组)、血管性认知障碍组(VCI组)和血管性认知障碍+睡眠碎片化组(VCI+SF组)。采用结扎双侧颈总动脉的方法制备大鼠血管性认知障碍模型。VCI+SF组和Sham+SF组于血管性认知障碍模型建立后第26天开始建立睡眠碎片化模型,第29天行条件性恐惧实验和旷场实验。条件性恐惧实验结束后,采用ELISA法检测海马TNF-α、IL-6含量,微板法检测海马SOD、谷胱甘肽过氧化物酶(GSH-Px)、MDA及铁含量,Western blot法检测NF-κB、caspase-3及谷胱甘肽过氧化物酶4(GPX4)表达水平。结果与Sham组相比,VCI组穿越格数、站立次数及僵直时间百分比降低,海马SOD及GSH-Px含量降低,MDA、IL-6、TNF-α及铁含量升高,NF-κB、caspase-3表达上调,GPX4表达下调(P<0.05);与Sham+SF组和VCI组相比,VCI+SF组穿越格数、站立次数及僵直时间百分比降低,海马SOD及GSH-Px含量降低,MDA、IL-6、TNF-α及铁含量升高,NF-κB、caspase-3表达上调,GPX4表达下调(P<0.05)。结论睡眠碎片化可加重大鼠血管性认知障碍,机制可能与诱导中枢炎症和氧化应激,导致海马神经细胞凋亡及铁死亡增加有关。 展开更多
关键词 睡眠觉醒障碍 痴呆 血管性 炎症 氧化性应激
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马属动物CG-β的生物信息学分析
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作者 汤驰 时士成 +2 位作者 廖清超 解鹏 邓亮 《生物技术》 CAS 2018年第6期579-584,共6页
[目的]采用生物信息学的方法对马属动物(马、驴和斑马)绒毛膜促性腺激素β(CG-β)的氨基酸组成、亲/疏水性、二级结构、糖基化位点和三级结构进行预测分析。[方法]利用多种分析软件对马属动物CG-β进行预测分析。[结果]马属动物CG-β脯... [目的]采用生物信息学的方法对马属动物(马、驴和斑马)绒毛膜促性腺激素β(CG-β)的氨基酸组成、亲/疏水性、二级结构、糖基化位点和三级结构进行预测分析。[方法]利用多种分析软件对马属动物CG-β进行预测分析。[结果]马属动物CG-β脯氨酸含量最高;二级结构均以β折叠为主要结构单元;dCG-β在13氨基酸位点发生N-糖基化,zCG-β在13和138氨基酸位点发生N-糖基化;dCG-β、zCG-β分别有14个和13个氨基酸位点发生O-糖基化;构建CG-β三级结构模型稳定可靠。[结论]马属动物CG-β均在29、48、84氨基酸位点附近呈现强疏水性,β折叠占比在50%以上,模型可靠性和稳定性达到标准。 展开更多
关键词 马属动物 CG-β 糖基化 生物信息学
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