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高清腹腔镜手术视频录像在胃肠外科临床带教中的体会 被引量:9
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作者 李利义 张良 +6 位作者 邱晓晓 陈健 陈馨鑫 池潇 游涛 沈贤 俞耀军 《教育教学论坛》 2020年第12期347-349,共3页
目的:为提高胃肠外科的带教水平和效果,探索高清腹腔镜手术视频录像在临床带教中的效果。方法:选取2017年7月—2018年7月期间进入胃肠外科的96名临床外科实习医师、研究生和低年制住院医师,每周进行胃肠外科腹腔镜手术视频观看,并安排... 目的:为提高胃肠外科的带教水平和效果,探索高清腹腔镜手术视频录像在临床带教中的效果。方法:选取2017年7月—2018年7月期间进入胃肠外科的96名临床外科实习医师、研究生和低年制住院医师,每周进行胃肠外科腹腔镜手术视频观看,并安排一名主治以上医师进行现场讲解和答疑。最后通过统一的出科考核并与上一年度的考试成绩进行对比,同时对学生进行问卷调查,评价教学效果。结果:出科考试的平均成绩为86.3±3.7分,高于上一年度的78.8±2.9分(P<0.05);问卷调查结果显示:认为对胃肠和腹部脏器的解剖知识掌握有帮助的达95.5%,对胃肠手术流程和解剖变异学习有帮助的达93.8%,对临床带教有帮助的达96.7%,对带教老师满意度高达100%。结论:视频观看的教学方式更加直观、形象,更具吸引力,更有利于学生掌握临床基础知识;同时可以有效地激发学生的学习兴趣,提高他们对带教的满意度。 展开更多
关键词 外科 带教 手术视频 满意度
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基于IBR模型研究BDE-47和BDE-153对半滑舌鳎的毒性效应 被引量:5
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作者 迟潇 陈碧鹃 +4 位作者 孙雪梅 朱琳 唐学玺 夏斌 曲克明 《生态毒理学报》 CAS CSCD 北大核心 2020年第4期192-202,共11页
多溴联苯醚(PBDEs)是应用广泛的溴代阻燃剂。选择2,2’,4,4’-四溴联苯醚(BDE-47)和2,2’,4,4’,5,5’-六溴联苯醚(BDE-153)对半滑舌鳎(Cynoglossus semilaevis Gunther)进行15 d的暴露实验,测定了不同暴露浓度下半滑舌鳎肝脏的超氧化... 多溴联苯醚(PBDEs)是应用广泛的溴代阻燃剂。选择2,2’,4,4’-四溴联苯醚(BDE-47)和2,2’,4,4’,5,5’-六溴联苯醚(BDE-153)对半滑舌鳎(Cynoglossus semilaevis Gunther)进行15 d的暴露实验,测定了不同暴露浓度下半滑舌鳎肝脏的超氧化物歧化酶(superoxide dismutase,SOD)、过氧化氢酶(catalase,CAT)、谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)、7-乙氧基-3-异吩恶唑酮-脱乙基酶(7-ethoxyresorufin-o-deethylase,EROD)的活性、雌激素受体(estrogen receptor,ER)和丙二醛(malondialdehyde,MDA)含量,并运用综合生物标志物响应(integrated biomarker response,IBR)模型研究BDE-47和BDE-153对半滑舌鳎的毒性效应。结果表明,环境浓度BDE-47和BDE-153暴露下半滑舌鳎的抗氧化酶活性、ER含量和EROD活性无显著变化;中高浓度组(500 ng·L^-1和50000 ng·L^-1)与对照组基本上都有显著差异。运用IBR方法进行计算发现,BDE-47和BDE-153对半滑舌鳎的毒性效应呈现出显著的剂量效应。将2种污染物暴露组IBR值进行比较,发现BDE-47各浓度组的IBR值均大于BDE-153组,这表明BDE-47的毒性要高于BDE-153。IBR指数能够有效地对PBDEs的海洋环境风险进行科学评价。 展开更多
关键词 BDE-47 BDE-153 半滑舌鳎 毒性效应 综合生物标志物响应
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BDE-47、BDE-99、BDE-153和BDE-209对蛋白核小球藻、大型溞和大菱鲆的急性毒性效应 被引量:2
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作者 迟潇 夏斌 +5 位作者 朱琳 陈碧鹃 孙雪梅 赵信国 唐学玺 曲克明 《渔业科学进展》 CSCD 北大核心 2019年第6期88-97,共10页
本研究选取4种多溴联苯醚(PBDEs)同系物(BDE-47、BDE-99、BDE-153和BDE-209)对蛋白核小球藻(Chlorella pyrenoidosa)、大型溞(Daphnia magna)和大菱鲆(Scophthalmus maximus)进行急性毒性实验。结果显示,4种PBDE同系物对蛋白核小球藻的9... 本研究选取4种多溴联苯醚(PBDEs)同系物(BDE-47、BDE-99、BDE-153和BDE-209)对蛋白核小球藻(Chlorella pyrenoidosa)、大型溞(Daphnia magna)和大菱鲆(Scophthalmus maximus)进行急性毒性实验。结果显示,4种PBDE同系物对蛋白核小球藻的96hEC50为1.39(BDE-47)、1.76(BDE-99)、3.23 (BDE-153)和378.62μg/L (BDE-209),安全浓度为0.10 (BDE-47)、0.18(BDE-99)、0.27 (BDE-153)和8.68μg/L (BDE-209);对大型溞的96 h LC50为0.24 (BDE-47)、1.42 (BDE-99)、1.49(BDE-153)和63.93μg/L (BDE-209),安全浓度为0.03 (BDE-47)、0.82 (BDE-99)、0.94 (BDE-153)和BDE-209 (5.09μg/L);对大菱鲆的96 h LC50为5.46(BDE-47)、6.07 (BDE-99)、7.35(BDE-153)和118.78μg/L (BDE-209),安全浓度为2.02 (BDE-47)、2.01 (BDE-99)、2.17 (BDE-153)和58.62μg/L(BDE-209)。多溴联苯醚同系物毒性随着溴原子取代数的增加而减小(BDE-47>BDE-99>BDE-153>BDE-209)。虽然目前海水中PBDEs处于安全浓度,但由于PBDEs的结构稳定性和环境持久性,其对环境的影响不容忽视。 展开更多
关键词 多溴联苯醚 蛋白核小球藻 大型溞 大菱鲆 急性毒性
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金属氧化物TFT阈值对LCD显示屏可靠性的影响 被引量:4
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作者 楼均辉 姜姝 +6 位作者 吴天一 符鞠建 夏兴达 何泽尚 迟宵 应变 李喜峰 《发光学报》 EI CAS CSCD 北大核心 2018年第3期383-387,共5页
TFT的器件特性是影响氧化物TFT驱动的LCD显示屏良率的关键因素。本文研究了氧化物TFT的关键特性参数(阈值,稳定性)对窄边框LCD显示屏的良率和可靠性的影响。氧化物TFT阈值过负,将会导致TFT无法正常关断,而使显示屏的外围移位寄存器(VSR... TFT的器件特性是影响氧化物TFT驱动的LCD显示屏良率的关键因素。本文研究了氧化物TFT的关键特性参数(阈值,稳定性)对窄边框LCD显示屏的良率和可靠性的影响。氧化物TFT阈值过负,将会导致TFT无法正常关断,而使显示屏的外围移位寄存器(VSR)电路失效。另外,在显示区域用于像素驱动的氧化物TFT的高温和背光照射下阈值持续负向漂移,最终会导致显示区域的驱动TFT漏电流过大,从而使显示屏出现串扰和残影不良。 展开更多
关键词 金属氧化物薄膜晶体管 阈值 LCD 可靠性
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Inversion of Venus internal structure based on geodetic data 被引量:2
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作者 chi xiao Fei Li +4 位作者 Jian-Guo Yan Wei-Feng Hao Yuji Harada Mao Ye Jean-Pierre Barriot 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2020年第8期237-251,共15页
Understanding the internal structure of Venus promotes the exploration of the evolutionary history of this planet.However,the existing research concerning the internal structure of Venus has not used any inversion met... Understanding the internal structure of Venus promotes the exploration of the evolutionary history of this planet.However,the existing research concerning the internal structure of Venus has not used any inversion methods.In this work we employed an inversion method to determine the internal structure of Venus using observational or hypothetical geodetic data;these data include mass,mean radius,mean moment of inertia and second degree tidal Love number k2.To determine the core state of Venus,we created two models of Venus,an isotropic 3-layer model with entire liquid core and an isotropic 4-layer model with liquid outer core and a solid inner core,assuming that the interior of Venus is spherically symmetric and in hydrostatic equilibrium.A series of the sensitivity analysis of interior structure parameters to the geodetic data considered in here shows that not all of the parameters can be constrained by the geodetic data from Venus.On this basis,a Markov Chain Monte Carlo algorithm was used to determine the posterior probability distribution and the optimal values of the internal structure parameters of Venus with the geodetic data.We found that the 3-layer model is more credible than the 4-layer model via currently geodetic data.For the assumption of the 3-layer model with the k2=0.295±0.066,I/MR^2=0.33±0.0165,andρ=5242.7±2.6 kg m^-3,the liquid iron-rich core of Venus has a radius of 3294+215-261km,which suggests a larger core than previous research has indicated.The average density of the mantle and liquid core of Venus are 4101+325-375and 11885+955-1242kg m~^-3,respectively. 展开更多
关键词 planets and satellites:interiors planets and satellites:terrestrial planets planets and satellites:physical evolution planets and satellites:fundamental parameters
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Synthesis and Improved Acetone Sensing Properties of Porous α-Fe_(2)O_(3) Nanowires
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作者 刘丽 迟霄 +5 位作者 王国光 刘唱白 陕皓 张晓波 王连元 关宏宇 《Chinese Physics Letters》 SCIE CAS CSCD 2013年第2期49-53,共5页
Porousα-Fe_(2)O_(3) nanowires are synthesized by a simple wet chemical method with a precursor of peroxyacetyl nitrate(PAN),andα-Fe_(2)O_(3) nanoparticles are also synthesized in the same way except for the addition... Porousα-Fe_(2)O_(3) nanowires are synthesized by a simple wet chemical method with a precursor of peroxyacetyl nitrate(PAN),andα-Fe_(2)O_(3) nanoparticles are also synthesized in the same way except for the addition of PAN.Gas sensors are fabricated by coating the samples on ceramic tubes with Au signal electrodes and Ni-Cr heaters.A sensing investigation reveals that the porousα-Fe_(2)O_(3) nanowires have a higher sensitivity compared toα-Fe_(2)O_(3) nanoparticles at 260℃.The corresponding sensor response(R_(a)/R_(g))is 18.2 at the maximum to 100 ppm acetone,and the response and recovery times are about 8 and 12 s,respectively.The porous and one-dimensional nanostructures of the porousα-Fe_(2)O_(3) nanowires benefit for the gas-absorption and electrical-signal-transfer,and thus improve the sensor sensitivity consequentially. 展开更多
关键词 NANOWIRES POROUS POROUS
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不同尺寸橡胶/帘线H型拉拔试验界面参数的归一化处理评价方法
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作者 王琮文 肖驰 +4 位作者 代玉静 王君 马寒松 郇勇 郇彦 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2024年第3期99-108,共10页
H型拉拔试验被广泛应用于橡胶/帘线复合材料界面粘结强度的估算.然而,目前的国际标准只要求在橡胶/帘线H型拉拔试验中记录拔出力的大小,并强调从不同尺寸的样品中获得的结果不具有可比性.在本文中,我们研究了不同尺寸橡胶/帘线试验样品... H型拉拔试验被广泛应用于橡胶/帘线复合材料界面粘结强度的估算.然而,目前的国际标准只要求在橡胶/帘线H型拉拔试验中记录拔出力的大小,并强调从不同尺寸的样品中获得的结果不具有可比性.在本文中,我们研究了不同尺寸橡胶/帘线试验样品的H拔出结果的可比性,并提出了一种归一化的评价方法来处理这些结果.分别对尺寸为5 mm、6.4 mm、10 mm的试验样品进行橡胶/帘线H拉拔试验(尺寸为7.5 mm、8.5 mm的试件结果作为支撑性试验).在试验结果的基础上,采用有限元法内聚单元模型对界面粘结强度进行了分析,所得出的内聚力参数比国际标准中所规定的拔出力更能准确地反映界面粘结性能.因此,采用内聚单元法能够更合理地比较不同橡胶/帘线试样的界面粘结强度.我们首先基于6.4 mm尺寸样品的试验结果建立有限元模型,并确定满足条件的内聚单元参数,然后将其应用于其他尺寸的样品模型.尽管试验样品的尺寸大小在变化,但在保持内聚单元参数不变的前提下,模拟结果与试验结果仍然保持良好的一致性,这表明内聚参数不受样本尺寸的影响.在此基础上,我们提出了一种归一化方法,使不同尺寸样品的橡胶/帘线H拉拔试验的结果具有了可比性.本文提出的归一化方法是对现有国际、国内标准实验方法的扩展. 展开更多
关键词 RUBBER COMPOSITES Finite element method Cohesive elements H pull-out test
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Gut microbiota signatures in Schistosoma japonicum infection-induced liver cirrhosis patients: a case-control study 被引量:2
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作者 Qi-Feng Gui Hui-Lin Jin +5 位作者 Feng Zhu Hai-Feng Lu Qin Zhang Jia Xu Yun-Mei Yang chi xiao 《Infectious Diseases of Poverty》 SCIE 2021年第2期83-83,共1页
Background:Several studies have assessed the role of gut microbiota in various cirrhosis etiologies,however,none has done so in the context of Schistosoma joponicum infection in humans.We,therefore,sought to determine... Background:Several studies have assessed the role of gut microbiota in various cirrhosis etiologies,however,none has done so in the context of Schistosoma joponicum infection in humans.We,therefore,sought to determine whether gut microbiota is associated with S.japonicum infection-induced liver cirrhosis.Methods:From December 2017 to November 2019,24 patients with S.joponicum infection-induced liver cirrhosis,as well as 25 age-and sex-matched controls from the Zhejiang Province,China,were enrolled.Fecal samples were collected and used for 16S rRNA gene sequencing(particularly,the hypervariable V4 region)using the lllumina MiSeq system.Wilcoxon Rank-Sum and PERMANOVA tests were used for analysis. 展开更多
关键词 Gut microbiota 16S rRNA Schistosoma joponicum
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论生成式大语言模型应用的安全性——以ChatGPT为例 被引量:4
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作者 熊明辉 池骁 《山东社会科学》 北大核心 2023年第5期79-90,共12页
以ChatGPT为代表的大语言模型的崛起,标志着人类向着通用人工智能迈出了巨大的一步,给人类带来更多的便利,但也将引发一些潜在风险。2023年4月11日国家互联网信息办公室发布了《生成式人工智能服务管理办法(征求意见稿)》。研究者应对Ch... 以ChatGPT为代表的大语言模型的崛起,标志着人类向着通用人工智能迈出了巨大的一步,给人类带来更多的便利,但也将引发一些潜在风险。2023年4月11日国家互联网信息办公室发布了《生成式人工智能服务管理办法(征求意见稿)》。研究者应对ChatGPT等人工智能语言模型进行负责任的创新,即在创新的同时对模型可能带来的风险具有前瞻性和更加深入的了解。针对ChatGPT存在的缺陷,我们要仔细考量大语言模型应用可能给人类带来的安全性问题,从使用者、研究者、监督者三个角度分析降低ChatGPT造成危害的可能对策,并给出法律规制建议,从而促进更公平、更负责的大语言模型的发展。 展开更多
关键词 通用人工智能 大语言模型 安全风险 法律规制
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Predicting and Visualizing Citrus Color Transformation Using a Deep Mask-Guided Generative Network
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作者 Zehan Bao Weifu Li +4 位作者 Jun Chen Hong Chen Vijay John chi xiao Yaohui Chen 《Plant Phenomics》 SCIE EI CSCD 2023年第3期435-446,共12页
Citrus rind color is a good indicator of fruit development,and methods to monitor and predict color transformation therefore help the decisions of crop management practices and harvest schedules.This work presents the... Citrus rind color is a good indicator of fruit development,and methods to monitor and predict color transformation therefore help the decisions of crop management practices and harvest schedules.This work presents the complete workflow to predict and visualize citrus color transformation in the orchard featuring high accuracy and fidelity.A total of 107 sample Navel oranges were observed during the color transformation period,resulting in a dataset containing 7,535 citrus images.A framework is proposed that integrates visual saliency into deep learning,and it consists of a segmentation network,a deep mask-guided generative network,and a loss network with manually designed loss functions.Moreover,the fusion of image features and temporal information enables one single model to predict the rind color at different time intervals,thus effectively shrinking the number of model parameters.The semantic segmentation network of the framework achieves the mean intersection over a union score of 0.9694,and the generative network obtains a peak signal-to-noise ratio of 30.01 and a mean local style loss score of 2.710,which indicate both high quality and similarity of the generated images and are also consistent with human perception.To ease the applications in the real world,the model is ported to an Android-based application for mobile devices.The methods can be readily expanded to other fruit crops with a color transformation period.The dataset and the source code are publicly available at GitHub. 展开更多
关键词 Visual DEEP NETWORK
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Indirectly extruded biodegradable Zn-0.05wt%Mg alloy with improved strength and ductility: In vitro and in vivo studies 被引量:16
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作者 chi xiao Liqing Wang +9 位作者 Yuping Ren Shineng Sun Erlin Zhang Chongnan Yan Qi Liu xiaogang Sun Fenyong Shou Jingzhu Duan Huang Wang Gaowu Qin 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2018年第9期1618-1627,共10页
As compared to permanent orthopedic implants for load-bearing applications, biodegradable orthopedic implants have the advantage of no need for removing after healing, but they suffer from the "trilemma" problem of ... As compared to permanent orthopedic implants for load-bearing applications, biodegradable orthopedic implants have the advantage of no need for removing after healing, but they suffer from the "trilemma" problem of compromising among sufficiently high mechanical properties, good biocompatibility and proper degradation rate conforming to the growth rate of new bones. In the present work, in vitro and in vivo studies of a Zn-0.05 wt%Mg alloy(namely, Zn-0.05 Mg alloy) were conducted with pure Zn as a control. The Zn-0.05 Mg alloy is composed of a small amount of Mg2 Zn11 phase embedded in the refined Zn matrix with an average grain size of ~20 μm. The addition of 0.05 wt% Mg into Zn significantly increases the ultimate tensile strength up to 225 MPa and the elongation to fracture to 26%, but has little influence on the in vitro degradation rate. Both Zn and Zn-0.05 Mg alloy exhibit homogeneous in vitro degradation with a rate of about 0.15 mm/year. Based on the cytotoxicity evaluation, Zn and Zn-0.05 Mg alloy do not induce toxicity to L-929 cells, indicating that they have little toxicity to the general functions of the animal. An in vivo biocompatibility study of Zn and Zn-0.05 Mg alloy samples by placing them in a rabbit model for 4.12 and 24 weeks, respectively did not show any inflammatory cells, and demonstrated that new bone tissue formed at the bone/implant interface, suggesting that Zn and Zn-0.05 Mg alloy promote the formation of new bone tissue. The in vivo degradation of Zn and Zn-0.05 Mg alloy does not bring harm to the important organs and their cell structures. More interestingly, Zn and Zn-0.05 Mg alloy exhibit strong antibacterial activity against Escherichia coli and Staphylococcus aureus. The above results clearly demonstrate that the Zn-0.05 Mg alloy could be a potential biodegradable orthopedic implant material. 展开更多
关键词 Zn-Mg alloy Mechanical properties BIODEGRADABILITY BIOCOMPATIBILITY Antibacterial activity
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Understanding the Moon's internal structure through moonquake observations and remote sensing technologies 被引量:2
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作者 Weifeng HAO Fei LI +2 位作者 chi xiao Jianguo YAN Mao YE 《Science China Earth Sciences》 SCIE EI CAS CSCD 2018年第8期995-1006,共12页
Explorations for the interior structure of the Moon mainly involve three technologies: the early gravitational observations via circumlunar satellites, the moonquake observations during the Apollo period, and the rece... Explorations for the interior structure of the Moon mainly involve three technologies: the early gravitational observations via circumlunar satellites, the moonquake observations during the Apollo period, and the recent high-resolution remote sensing observations. Based on these technologies, we divided the development of the moon's interior structure into three stages. The first stage is the discovery of high-density anomalous masses(mascons) on the lunar surface with the low-order gravitational field models, which were obtained by observing perturbations of the early lunar orbital satellites. The second stage is the preliminary understanding of the layer structure with the help of moonquake observations during the Apollo period. The third stage is the deep understanding of the structure of the lunar crust, mantle, and core, with the use of high-resolution remote sensing data and the reassessment of moonquake data from the Apollo's mission. This paper gave detailed introduction and comments on different observation technologies, gathered data, and data processing techniques used at the three stages. In addition, this paper analyzed the current issues in the researches on the Moon's internal structure and discussed the prospects for future explorations. 展开更多
关键词 内部结构 遥感技术 月亮 数据处理技术 高分辨率 阿波罗 遥感数据 异常群
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Synthesis and acetone gas sensing properties of α-Fe_2O_3 nanotubes 被引量:2
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作者 SHAN Hao LIU ChangBai +5 位作者 LIU Li WANG LianYuan LI ShouChun ZHANG xiaoBo BO xiaoQing chi xiao 《Science China Chemistry》 SCIE EI CAS 2013年第12期1722-1726,共5页
α-Fe2O3nanotubes was successfully prepared by single nozzle electrospinning method.Scanning electron microscope(SEM)was used to characterize the morphology of-Fe2O3nanotubes.The gas sensing properties of-Fe2O3nanotub... α-Fe2O3nanotubes was successfully prepared by single nozzle electrospinning method.Scanning electron microscope(SEM)was used to characterize the morphology of-Fe2O3nanotubes.The gas sensing properties of-Fe2O3nanotubes were investigated in detail.The results exhibit relatively good sensing properties to acetone at 240°C.The response and recovery times are about 3 and 5 s,respectively.The structure of nanotubes is beneficial to the gas sensing properties,which will enlarge the surface-to-volume ratio of α-Fe2O3and then be available for the transfer of gas,and thus improved the sensor performance consequentially. 展开更多
关键词 碳纳米管 气敏特性 丙酮 扫描电子显微镜 合成 气敏性能 静电纺丝法 传感性能
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