Objective:This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep,ovarian,and pelvic endometriosis. Study design:The clinical data of 1106 wom...Objective:This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep,ovarian,and pelvic endometriosis. Study design:The clinical data of 1106 women with first diagnosis of endometriosis observed between 1979 and 2001 were collected. Results:The 4-year recurrence rate was 24.6%,17.8%,30.6%and 23.7%,respectively,for cases of ovarian,pelvic,deep,and ovarian and pelvic endometriosis (P < .05). The recurrence rates decreased in all groups (with the exception of ovarian endometriosis) in the class age 34 years or older,these findings were significant (P < .05). Radicalitywas associated with lower recurrence rates in all the groups. A pregnancy after diagnosis was associated with a reduced risk of recurrence. Conclusion:The study shows that the recurrence rates of endometriosis were higher in case of deep endometriosis and that the risk factors for recurrence were similar among women with endometriosis at different sites.展开更多
Objective: To analyse risk factors for bacterial vaginosis (BV). Study design: We conducted a casecontrol study on risk factors for BV, in several firstlevel gynecological centers in Italy. Cases were women aged 1...Objective: To analyse risk factors for bacterial vaginosis (BV). Study design: We conducted a casecontrol study on risk factors for BV, in several firstlevel gynecological centers in Italy. Cases were women aged 18-70 years with confirmed diagnosis of BV (using test for proline iminopeptidase (PIP) activity). Control were the first patients observed in the same center without any symptom suggesting vaginal infection, and a negative PIP activity test. A total of 476 cases and 450 controls entered the study. Results: The number of sexual partners in the month before interview, but not the number of intercourses, was associated with an increased risk of BV. The risk of BV with vaginal douching or tight jeans/trousers once or more a week was 2.0 (95%CI 1.0-3.9) and 1.5 (95%CI 1.0-2.2), respectively, compared to never users. Conclusion: The findings are consistent with previous data and suggest that daily habits play an important role in risk of BV.展开更多
Objectives. Breastfeeding has been inversely related to the risk of ovarian cancer, but results from published studies are inconsistent. In order to provide further information, we analyzed data from a large case-cont...Objectives. Breastfeeding has been inversely related to the risk of ovarian cancer, but results from published studies are inconsistent. In order to provide further information, we analyzed data from a large case-control study conducted in four Italian areas. Methods. Cases were 1031 women with epithelial ovarian cancer. Controls were 2411 women admitted to the same network of hospitals for a wide spectrum of acute non-neoplastic conditions, unrelated to known risk factors for ovarian cancer. Results. There were inverse trends in risk with increasing duration of breastfeeding and number of children breastfed, but when parity and several other potential confounding factors were taken into account, no residual association was evident (odds ratio = 1.21 for 17 or more months of breastfeeding and 0.90 for those who had breastfed 4 or more children, as compared to women who had never breastfed). Conclusions. This study showed an inverse relation between breastfeeding and ovarian cancer risk, which however was accounted for by parity. The analyses by histologic subtypes suggested that a role of breastfeeding would be larger for serous neoplasms in the absence, however, of significant heterogeneity.展开更多
文摘Objective:This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep,ovarian,and pelvic endometriosis. Study design:The clinical data of 1106 women with first diagnosis of endometriosis observed between 1979 and 2001 were collected. Results:The 4-year recurrence rate was 24.6%,17.8%,30.6%and 23.7%,respectively,for cases of ovarian,pelvic,deep,and ovarian and pelvic endometriosis (P < .05). The recurrence rates decreased in all groups (with the exception of ovarian endometriosis) in the class age 34 years or older,these findings were significant (P < .05). Radicalitywas associated with lower recurrence rates in all the groups. A pregnancy after diagnosis was associated with a reduced risk of recurrence. Conclusion:The study shows that the recurrence rates of endometriosis were higher in case of deep endometriosis and that the risk factors for recurrence were similar among women with endometriosis at different sites.
文摘Objective: To analyse risk factors for bacterial vaginosis (BV). Study design: We conducted a casecontrol study on risk factors for BV, in several firstlevel gynecological centers in Italy. Cases were women aged 18-70 years with confirmed diagnosis of BV (using test for proline iminopeptidase (PIP) activity). Control were the first patients observed in the same center without any symptom suggesting vaginal infection, and a negative PIP activity test. A total of 476 cases and 450 controls entered the study. Results: The number of sexual partners in the month before interview, but not the number of intercourses, was associated with an increased risk of BV. The risk of BV with vaginal douching or tight jeans/trousers once or more a week was 2.0 (95%CI 1.0-3.9) and 1.5 (95%CI 1.0-2.2), respectively, compared to never users. Conclusion: The findings are consistent with previous data and suggest that daily habits play an important role in risk of BV.
文摘Objectives. Breastfeeding has been inversely related to the risk of ovarian cancer, but results from published studies are inconsistent. In order to provide further information, we analyzed data from a large case-control study conducted in four Italian areas. Methods. Cases were 1031 women with epithelial ovarian cancer. Controls were 2411 women admitted to the same network of hospitals for a wide spectrum of acute non-neoplastic conditions, unrelated to known risk factors for ovarian cancer. Results. There were inverse trends in risk with increasing duration of breastfeeding and number of children breastfed, but when parity and several other potential confounding factors were taken into account, no residual association was evident (odds ratio = 1.21 for 17 or more months of breastfeeding and 0.90 for those who had breastfed 4 or more children, as compared to women who had never breastfed). Conclusions. This study showed an inverse relation between breastfeeding and ovarian cancer risk, which however was accounted for by parity. The analyses by histologic subtypes suggested that a role of breastfeeding would be larger for serous neoplasms in the absence, however, of significant heterogeneity.
