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Synthesis and Bioactivity of 1-((2-Carbamoylguanidino) (furan-2-ylmethyl)urea
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作者 chioma donlawson Daniel Okechukwu Nweneka +1 位作者 Kingsley John Orie Reminus Okah 《American Journal of Analytical Chemistry》 2020年第7期280-288,共9页
1-((2-Carbamoylguanidino)(furan-2-ylmethyl)urea was synthesised by coupling purified furfural with urea. The compound was characterized by GC-MS, FTIR, and <sup>1</sup>H-NMR. The pathogens, <i>Escher... 1-((2-Carbamoylguanidino)(furan-2-ylmethyl)urea was synthesised by coupling purified furfural with urea. The compound was characterized by GC-MS, FTIR, and <sup>1</sup>H-NMR. The pathogens, <i>Escherichia coli</i>, <i>Salmonella typhi</i>, <i>Staphylococcus aureus</i> and <i>Bacillus subtilis</i> were isolated and screened with different concentrations of 1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea. All the pathogens were susceptible to the synthesized compound except Bacillus subtilis. Due to this broad spectrum of activity, 1-((2-Carbamoylguanidino)(furan-2-ylmethyl))urea) can be use for various medicinal purposes and is therefore encouraged for the development of a novel drug in future. 展开更多
关键词 FURFURAL 1-((2-Carbamoylguanidino)(furan-2-ylmethyl)urea Bioactivity
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