To reveal the pathogenesis of myopic foveoschisis (MF)-. Clinicopathological report. Internal limiting membranes (ILMs) were collected from ten patients with MF and five patients with idiopathicmacular hole (IMH) as a...To reveal the pathogenesis of myopic foveoschisis (MF)-. Clinicopathological report. Internal limiting membranes (ILMs) were collected from ten patients with MF and five patients with idiopathicmacular hole (IMH) as a control. Samples were subjected to transmission electronmicroscopic study. Characteristics of the ILM were compared between the two groups. Collagen fiber and cell debris were identified on the inner surface of ILM in seven eyes (70% )with MF, significantly more (P< .05) than found in IMH subjects (0% ). More fibrous glial cells were likely to be found on the inner surface of ILM. No significant difference in fibroblast-like cell adhesion was observed. Collagen fiber and cellular component are suggested to play an important role in developing MF. ILM peeling may be essential for vitrectomy for MF.展开更多
To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachme nt (MHRD) as a result of high myopia. Histologic study. We...To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachme nt (MHRD) as a result of high myopia. Histologic study. We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retina l surface during vitrectomy and examined them by transmission electron microscop y. The first membrane was made of acellular collagen fibers, suggestive of vitre ous, and the second was comprised of parts of fibro-blast-like cells and colla gen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane. Multiple components of epiretinal tissue coul d be delaminated with the assistance of TA and ICG during surgery for myopic MHR D.展开更多
文摘To reveal the pathogenesis of myopic foveoschisis (MF)-. Clinicopathological report. Internal limiting membranes (ILMs) were collected from ten patients with MF and five patients with idiopathicmacular hole (IMH) as a control. Samples were subjected to transmission electronmicroscopic study. Characteristics of the ILM were compared between the two groups. Collagen fiber and cell debris were identified on the inner surface of ILM in seven eyes (70% )with MF, significantly more (P< .05) than found in IMH subjects (0% ). More fibrous glial cells were likely to be found on the inner surface of ILM. No significant difference in fibroblast-like cell adhesion was observed. Collagen fiber and cellular component are suggested to play an important role in developing MF. ILM peeling may be essential for vitrectomy for MF.
文摘To examine three layers of membranes detected by triamcinolone acetonide (TA) and indocyanine green (ICG) during surgery for macular hole and retinal detachme nt (MHRD) as a result of high myopia. Histologic study. We excised three layers of membranes visualized with TA and ICG that were tightly adhering to the retina l surface during vitrectomy and examined them by transmission electron microscop y. The first membrane was made of acellular collagen fibers, suggestive of vitre ous, and the second was comprised of parts of fibro-blast-like cells and colla gen fibrils, suggesting a proliferative epiretinal membrane. The third membrane was an internal limiting membrane. Multiple components of epiretinal tissue coul d be delaminated with the assistance of TA and ICG during surgery for myopic MHR D.
