AIM: To systematically evaluate the efficacy and safety of endoscopic resection of gastrointestinal smooth muscle tumors (SMTs, including leiomyoma and leiomyosarcoma) and to review our preliminary experiences on endo...AIM: To systematically evaluate the efficacy and safety of endoscopic resection of gastrointestinal smooth muscle tumors (SMTs, including leiomyoma and leiomyosarcoma) and to review our preliminary experiences on endoscopic diagnosis of gastrointestinal SMTs. METHODS: A total of 69 patients with gastrointestinal SMT underwent routine endoscopy in our department. Endoscopic ultrasonography (EUS) was also performed in 9 cases of gastrointestinal SMT. The sessile submucosal gastrointestinal SMTs with the base smaller than 2 cm in diameter were resected by "pushing" technique or "grasping and pushing" technique while the pedunculated SMTs were resected by polypectomy. For those SMTs originating from muscularis propria or with the base size ≥ 2 cm, ordinary biopsy technique was performed in tumors with ulcers while the "Digging" technique was performed in those without ulcers. RESULTS: 54 cases of leiomyoma and 15 cases of leiomyosarcoma were identified. In them, 19 cases of submucosal leiomyoma were resected by "pushing" technique and 10 cases were removed by "grasping and pushing" technique. Three cases pedunculated submucosal leiomyoma were resected by polypectomy. No severe complications developed during or after the procedure. No recurrence was observed. The diagnostic accuracy of ordinary and the "Digging" biopsy technique was 90.0% and 94.1%, respectively. CONCLUSION: Endoscopic resection is a safe and effective treatment for leiomyomas with the base size ≤2 cm. The "digging" biopsy technique would be a good option for histologic diagnosis of SMTs.展开更多
During the past two decades, a number of studies have investigated the health-related quality of life (HRQOL) of older people with visual impairment, but the information is fragmented concerning health care providers ...During the past two decades, a number of studies have investigated the health-related quality of life (HRQOL) of older people with visual impairment, but the information is fragmented concerning health care providers in the field of gerontology. In this review, findings of HRQOL studies in older adults with different types of age-related ocular disorders or conditions are summarized. Apart from medical treatment and vision rehabilitation, factors that may influence the HRQOL of visually impaired older adults are also examined, including age, gender, socioeconomic status, mobility, comorbidity, family support, social support, use of eye care services, and psychological and spiritual factors. Finally, existing problems are discussed and recommendations for future research are provided. Given the high prevalence of visual impairment among older adults and their unmet needs for eye care and vision rehabilitation, multidisciplinary interventions that may enhance visually impaired older people’s HRQOL are warranted.展开更多
文摘AIM: To systematically evaluate the efficacy and safety of endoscopic resection of gastrointestinal smooth muscle tumors (SMTs, including leiomyoma and leiomyosarcoma) and to review our preliminary experiences on endoscopic diagnosis of gastrointestinal SMTs. METHODS: A total of 69 patients with gastrointestinal SMT underwent routine endoscopy in our department. Endoscopic ultrasonography (EUS) was also performed in 9 cases of gastrointestinal SMT. The sessile submucosal gastrointestinal SMTs with the base smaller than 2 cm in diameter were resected by "pushing" technique or "grasping and pushing" technique while the pedunculated SMTs were resected by polypectomy. For those SMTs originating from muscularis propria or with the base size ≥ 2 cm, ordinary biopsy technique was performed in tumors with ulcers while the "Digging" technique was performed in those without ulcers. RESULTS: 54 cases of leiomyoma and 15 cases of leiomyosarcoma were identified. In them, 19 cases of submucosal leiomyoma were resected by "pushing" technique and 10 cases were removed by "grasping and pushing" technique. Three cases pedunculated submucosal leiomyoma were resected by polypectomy. No severe complications developed during or after the procedure. No recurrence was observed. The diagnostic accuracy of ordinary and the "Digging" biopsy technique was 90.0% and 94.1%, respectively. CONCLUSION: Endoscopic resection is a safe and effective treatment for leiomyomas with the base size ≤2 cm. The "digging" biopsy technique would be a good option for histologic diagnosis of SMTs.
文摘During the past two decades, a number of studies have investigated the health-related quality of life (HRQOL) of older people with visual impairment, but the information is fragmented concerning health care providers in the field of gerontology. In this review, findings of HRQOL studies in older adults with different types of age-related ocular disorders or conditions are summarized. Apart from medical treatment and vision rehabilitation, factors that may influence the HRQOL of visually impaired older adults are also examined, including age, gender, socioeconomic status, mobility, comorbidity, family support, social support, use of eye care services, and psychological and spiritual factors. Finally, existing problems are discussed and recommendations for future research are provided. Given the high prevalence of visual impairment among older adults and their unmet needs for eye care and vision rehabilitation, multidisciplinary interventions that may enhance visually impaired older people’s HRQOL are warranted.