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Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak
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作者 Kyleyoung LOW Layching CHAI +4 位作者 choonweng lee Gan ZHANG Ruijie ZHANG Vaezzadeh VAHAB Chuiwei BONG 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2021年第1期122-134,共13页
Antibiotics released into the environment through anthropogenic activities exert selective pressure,driving bacteria towards increasing antimicrobial resistance.The prevalence of antibiotics and the ecological risks p... Antibiotics released into the environment through anthropogenic activities exert selective pressure,driving bacteria towards increasing antimicrobial resistance.The prevalence of antibiotics and the ecological risks posed in the riverine estuarine of Larut River and Sangga Besar River,which included wastewater effl uents from hospital,zoo,and poultry slaughterhouse sources were investigated.Solid phase extraction(SPE)followed by high-performance liquid chromatography tandem mass chromatography(HPLC-MS/MS)were used to extract and quantify the antibiotic residues from 22 antibiotics belonging to six major antibiotic classes(sulfonamide,macrolide,fl uoroquinolone,phenicol,trimethoprim,and tetracycline).Sixteen antibiotic residues were detected with concentrations ranging from limit of detection(LOD)to 1262.3 ng/L.Fluoroquinolones and macrolides were the most frequently detected compounds.Erythromycin,clarithromycin,and ofl oxacin detected in hospital and zoo effl uents posed a high risk to algae while tetracycline had low to medium ecological risks toward all the relevant organisms from aquatic environments(algae,invertebrate Daphnia magna,and fi sh). 展开更多
关键词 antibiotic residues PREVALENCE ecological risk anthropogenic pollution RIVERINE ESTUARINE
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