Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic rim.We report the case of a 57-year-old w...Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic rim.We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma.Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features,including multifocality,a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis.The diagnosis,imaging,and histological appearance of xanthoma of bone are reviewed.展开更多
文摘Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic rim.We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma.Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features,including multifocality,a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis.The diagnosis,imaging,and histological appearance of xanthoma of bone are reviewed.
