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Bacterial translocation in patients undergoing major gastrointestinal surgery and its role in postoperative sepsis 被引量:2
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作者 Christos Doudakmanis Konstantinos Bouliaris +2 位作者 christina kolla Matthaios Efthimiou Georgios D Koukoulis 《World Journal of Gastrointestinal Pathophysiology》 2021年第6期106-114,共9页
Bacteria of the human intestinal microflora have a dual role.They promote digestion and are part of a defense mechanism against pathogens.These bacteria could become potential pathogens under certain circumstances.The... Bacteria of the human intestinal microflora have a dual role.They promote digestion and are part of a defense mechanism against pathogens.These bacteria could become potential pathogens under certain circumstances.The term“bacterial translocation”describes the passage of bacteria of the gastrointestinal tract through the intestinal mucosa barrier to mesenteric lymph nodes and other organs.In some cases,the passage of bacteria and endotoxins could result in blood stream infections and in multiple organ failure.Open elective abdominal surgery more frequently results in malfunction of the intestinal barrier and subsequent bacterial translocation and blood stream infections than laparoscopic surgery.Postoperative sepsis is a common finding in patients who have undergone non-elective abdominal surgeries,including trauma patients treated with laparotomy.Postoperative sepsis is an emerging issue,as it changes the treatment plan in surgical patients and prolongs hospital stay.The association between bacterial translocation and postoperative sepsis could provide novel treatment options. 展开更多
关键词 Bacterial translocation Major gastrointestinal surgery Postoperative sepsis Intestinal permeability MICROBIOTA
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Laparoscopic bilateral inguinal hernia repair: Should it be the preferred technique? 被引量:1
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作者 Christos Doudakmanis christina kolla +2 位作者 Konstantinos Bouliaris Matthaios Efthimiou Georgios D Koukoulis 《World Journal of Methodology》 2022年第4期193-199,共7页
Inguinal hernias are amongst the most common conditions requiring general surgical intervention.For decades,the preferred approach was the open repair.As laparoscopy became more popular and available and more surgeons... Inguinal hernias are amongst the most common conditions requiring general surgical intervention.For decades,the preferred approach was the open repair.As laparoscopy became more popular and available and more surgeons became familiarized with this modality,laparoscopic inguinal hernia repair became an alternative.The aim of this study is to assess the effectiveness of laparoscopic inguinal repair,with a focus on bilateral inguinal hernias.Initial reports have shown promising clinical outcomes compared to those of conventional repair of bilateral hernias.However,there are only a few studies concerning laparoscopic repair of bilateral hernias.It is yet to be proven that laparoscopy is the“gold standard”in the treatment of bilateral inguinal hernias.So far,the choice of an inguinal hernia repair technique has been up to each surgeon,depending on their expertise and available resources after taking into consideration each patient’s needs. 展开更多
关键词 Bilateral inguinal hernia Laparoscopic repair Open repair:Gold standard Chronic pain RECURRENCE
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