这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织（European Stroke Organisation, ESO）-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排，在2015年利用新的临床试验数据对该声明进...这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织（European Stroke Organisation, ESO）-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排，在2015年利用新的临床试验数据对该声明进行了更新。2015年2月，在瑞士伯尔尼召开的ESO冬季培训会期间组织了面对面会议对共识声明进行修订，然后通过电子邮件交换意见，最终版本得到各学会的认可。推荐意见与原始版本一致，证据等级更新到2015年2月20日为止，在2015年5月15日获得确认。ESO-卡罗林斯卡卒中更新会议的目的在于总结卒中治疗研究的最新进展并探讨如何将这些最新研究结果应用于临床实践。共识会议选择了一些议题进行讨论，与会者草拟一份共识声明并进行讨论。该声明接受了ESO指南委员会的指导。这份共识声明包括对急性卒中后机械取栓治疗的推荐意见，得到欧洲卒中组织ESO、欧洲神经微创治疗学会（European Society of Minimally Invasive Neurological Therapy, ESMINT）、欧洲神经放射学学会（European Society of Neuroradiology, ESNR）和欧洲神经病学学会（European Academy of Neurology, EAN）的支持。展开更多
Treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded artery.In recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retr...Treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded artery.In recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy procedure.Despite ongoing developments and progress in AIS imaging techniques,it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of treatment.Intraprocedural devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS patients.In this review,what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been examined.This review also discusses the evidence that AIS thrombus composition varies with aetiology,questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of treatment.Furthermore,this review discusses the evidence that current widely used radiological imaging tools can predict thrombus composition.Further use of new emerging technologies based on bioimpedance,as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been introduced.Whether bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed.展开更多
文摘这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织（European Stroke Organisation, ESO）-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排，在2015年利用新的临床试验数据对该声明进行了更新。2015年2月，在瑞士伯尔尼召开的ESO冬季培训会期间组织了面对面会议对共识声明进行修订，然后通过电子邮件交换意见，最终版本得到各学会的认可。推荐意见与原始版本一致，证据等级更新到2015年2月20日为止，在2015年5月15日获得确认。ESO-卡罗林斯卡卒中更新会议的目的在于总结卒中治疗研究的最新进展并探讨如何将这些最新研究结果应用于临床实践。共识会议选择了一些议题进行讨论，与会者草拟一份共识声明并进行讨论。该声明接受了ESO指南委员会的指导。这份共识声明包括对急性卒中后机械取栓治疗的推荐意见，得到欧洲卒中组织ESO、欧洲神经微创治疗学会（European Society of Minimally Invasive Neurological Therapy, ESMINT）、欧洲神经放射学学会（European Society of Neuroradiology, ESNR）和欧洲神经病学学会（European Academy of Neurology, EAN）的支持。
基金funded by European Regional Development Fund(13/RC/2073_2)Sensome(No grant number),Science Foundation Ireland(13/RC/2073_2).
文摘Treatment of acute ischaemic stroke(AIS)focuses on rapid recanalisation of the occluded artery.In recent years,advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy procedure.Despite ongoing developments and progress in AIS imaging techniques,it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of treatment.Intraprocedural devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS patients.In this review,what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been examined.This review also discusses the evidence that AIS thrombus composition varies with aetiology,questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of treatment.Furthermore,this review discusses the evidence that current widely used radiological imaging tools can predict thrombus composition.Further use of new emerging technologies based on bioimpedance,as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been introduced.Whether bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed.
