The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional e...The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.展开更多
目的探讨COX-2 mRNA在膝骨关节炎(KOA)病变过程中的作用。方法 76例膝骨关节炎患者(研究组)根据病变进展分为初期、中期、晚期三组,选取15例非膝骨关节炎患者为对照组,比较各组的COX-2 m RNA以及COX-2蛋白表达水平。结果研究组、初期组...目的探讨COX-2 mRNA在膝骨关节炎(KOA)病变过程中的作用。方法 76例膝骨关节炎患者(研究组)根据病变进展分为初期、中期、晚期三组,选取15例非膝骨关节炎患者为对照组,比较各组的COX-2 m RNA以及COX-2蛋白表达水平。结果研究组、初期组、中期组、晚期组的成纤维样滑膜细胞中COX-2 mRNA及蛋白表达灰度值显著高于对照组(P<0.05);初期组的成纤维样滑膜细胞中COX-2 mRNA及蛋白表达灰度值显著高于中期组、晚期组(P <0.05)。结论 COX-2mRNA在膝骨关节炎患者病变初期表达水平较高,检测COX-2 m RNA表达水平有助于为膝骨关节炎患者的诊治及预后提供指导。展开更多
基金supported by the Sichuan Social Science Planning Project (General Project)“Research on the Development of Rural Tourism Sharing Economy in Sichuan from the Perspective of Rural Revitalization Strategy and All-for-one Tourism” (SC20B133)the Humanities and Social Sciences Research Special Fund Cultivation Project (2022-2023RW021)of Southwest Petroleum University。
文摘The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.
