Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products.In order to determine the genetic control of pod shape,six component traits of pod shape(pod length,pod width,pod l...Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products.In order to determine the genetic control of pod shape,six component traits of pod shape(pod length,pod width,pod length/width ratio,pod roundness,beak degree and constriction degree)were measured using an image-based phenotyping method.A recombinant inbred line(RIL)population consisting of 181 lines was phenotyped across three environments.Continuous distributions and transgressive segregations were demonstrated in all measured traits and environments.Significant correlations were found among most component traits with broad-sense heritability ranging from 0.87 to 0.95.Quantitative trait locus(QTL)analysis yielded 26 additive QTLs explaining 3.79 to 52.37%phenotypic variations.A novel,stable and major QTL region conditioning multiple shape features was detected on chromosome 2,which spans a 10.81-Mb genomic region with 543 putative genes.Bioinformatics analysis revealed several candidate genes in this region.In addition,73 pairs of epistatic interactions involving 92 loci were identified for six component traits explaining 0.94–6.45%phenotypic variations.These results provide new genetic loci to facilitate genomics-assisted breeding of peanut pod shape.展开更多
目的研究分析急性发作期支气管哮喘病人哮喘感知控制力(perceived control of asthma,PCA)水平及其影响因素。方法采取方便抽样的方法,于2015年1月至2018年5月调查张家港地区两家三级乙等综合性医院(张家港市中医医院,张家港市第一人民...目的研究分析急性发作期支气管哮喘病人哮喘感知控制力(perceived control of asthma,PCA)水平及其影响因素。方法采取方便抽样的方法,于2015年1月至2018年5月调查张家港地区两家三级乙等综合性医院(张家港市中医医院,张家港市第一人民医院)共248例急性发作期支气管哮喘病人和250例哮喘慢性持续期病人的感知控制力现状,采用问卷调查的方法收集资料,对影响病人感知控制力现状的相关因素进行分析。结果本研究中248例病人急性发作期哮喘病人PCA总分(32.94±3.51)分明显低于哮喘慢性持续期病人(39.85±4.01)分,差异有统计学意义(t=20.455,P<0.05)。单因素分析结果显示,年龄、文化程度、是否接受哮喘教育、是否合并过敏性鼻炎、第1秒用力呼气容积占预计值百分比(FEV1%)、哮喘病程、血嗜酸粒细胞水平与哮喘病人PCA总评分密切相关(P<0.05)。多元线性回归分析显示,是否合并过敏性鼻炎、哮喘病程以及血嗜酸粒细胞水平是影响PCA水平的独立危险因素(P<0.05)。结论急性发作期哮喘病人PCA水平明显低于哮喘慢性持续期病人,是否合并过敏性鼻炎、哮喘病程以及血嗜酸粒细胞水平是影响急性发作期哮喘病人PCA总分的独立危险因素。展开更多
Skyrmions are nano-scale quasi-particles with topological protection,which have potential applications in next-generation spintronics-based information storage.Numerous papers have been published to review various asp...Skyrmions are nano-scale quasi-particles with topological protection,which have potential applications in next-generation spintronics-based information storage.Numerous papers have been published to review various aspects of skyrmions,including physics,materials and applications.However,no review paper has focused on rare metals which play important roles in nucleating and manipulating skyrmions and other topological states.In this paper,various roles of rare metals have been classified and summarized,which can tune Curie temperature(TC),Dzyaloshinskii-Moriya interaction(DMI),magnetocrystalline anisotropy,Ruderman-Kittel-Kasuya-Yosida(RKKY)interaction and four-spin interaction so as to trigger the generation of skyrmions and other topological spin structures.The materials covered include typical B20 crystals,various layered systems with interfacial DMI,frustrated materials,antiferromagnets,ferrimagnets,twodimensional(2D)materials,etc.In addition,the rare-earth(RE)permanent magnets can provide an energy barrier and enrich the dynamic behaviors of skyrmions,which has also been reviewed.展开更多
基金supported by the National Natural Science Foundation of China(32001584)the Natural Science Foundation of Shandong Province,China(ZR202111290099)+2 种基金the Breeding Project from Department Science&Technology of Shandong Province,China(2020LZGC001)the Agricultural Scientific and the Technological Innovation Project of Shandong Academy of Agricultural Sciences,China(CXGC2022A21,CXGC2022A03,and CXGC2023A06(A39 and A46))the Qingdao People’s Livelihood Science and Technology Program,China(20-3-4-26-nsh)。
文摘Peanut pod shape is a heritable trait which affects the market acceptance of in-shell peanut products.In order to determine the genetic control of pod shape,six component traits of pod shape(pod length,pod width,pod length/width ratio,pod roundness,beak degree and constriction degree)were measured using an image-based phenotyping method.A recombinant inbred line(RIL)population consisting of 181 lines was phenotyped across three environments.Continuous distributions and transgressive segregations were demonstrated in all measured traits and environments.Significant correlations were found among most component traits with broad-sense heritability ranging from 0.87 to 0.95.Quantitative trait locus(QTL)analysis yielded 26 additive QTLs explaining 3.79 to 52.37%phenotypic variations.A novel,stable and major QTL region conditioning multiple shape features was detected on chromosome 2,which spans a 10.81-Mb genomic region with 543 putative genes.Bioinformatics analysis revealed several candidate genes in this region.In addition,73 pairs of epistatic interactions involving 92 loci were identified for six component traits explaining 0.94–6.45%phenotypic variations.These results provide new genetic loci to facilitate genomics-assisted breeding of peanut pod shape.
文摘目的研究分析急性发作期支气管哮喘病人哮喘感知控制力(perceived control of asthma,PCA)水平及其影响因素。方法采取方便抽样的方法,于2015年1月至2018年5月调查张家港地区两家三级乙等综合性医院(张家港市中医医院,张家港市第一人民医院)共248例急性发作期支气管哮喘病人和250例哮喘慢性持续期病人的感知控制力现状,采用问卷调查的方法收集资料,对影响病人感知控制力现状的相关因素进行分析。结果本研究中248例病人急性发作期哮喘病人PCA总分(32.94±3.51)分明显低于哮喘慢性持续期病人(39.85±4.01)分,差异有统计学意义(t=20.455,P<0.05)。单因素分析结果显示,年龄、文化程度、是否接受哮喘教育、是否合并过敏性鼻炎、第1秒用力呼气容积占预计值百分比(FEV1%)、哮喘病程、血嗜酸粒细胞水平与哮喘病人PCA总评分密切相关(P<0.05)。多元线性回归分析显示,是否合并过敏性鼻炎、哮喘病程以及血嗜酸粒细胞水平是影响PCA水平的独立危险因素(P<0.05)。结论急性发作期哮喘病人PCA水平明显低于哮喘慢性持续期病人,是否合并过敏性鼻炎、哮喘病程以及血嗜酸粒细胞水平是影响急性发作期哮喘病人PCA总分的独立危险因素。
基金financially supported by the National Natural Science Foundation of China (Nos. 51771127, 52171188 52111530143, 12104327, 51901081, 11974298 and 61961136006)the National Key Research and Development Program of China (No. 2020YFA0309300)+6 种基金Sichuan Science and Technology Program (Application No. 21ZYZYTS0077)the Science and Technology Program of Guangzhou (No. 202002030052)Guangdong Special Support Project (No. 2019BT02X030)Shenzhen Fundamental Research Fund (No. JCYJ20210324120213037)Shenzhen Peacock Group Plan (No. KQTD20180413181702403)Pearl River Recruitment Program of Talents (No. 2017GC010293)the Grants-in-Aid for Scientific Research from JSPS KAKENHI (Nos. JP20F20363, JP21H01364 and JP21K18872)
文摘Skyrmions are nano-scale quasi-particles with topological protection,which have potential applications in next-generation spintronics-based information storage.Numerous papers have been published to review various aspects of skyrmions,including physics,materials and applications.However,no review paper has focused on rare metals which play important roles in nucleating and manipulating skyrmions and other topological states.In this paper,various roles of rare metals have been classified and summarized,which can tune Curie temperature(TC),Dzyaloshinskii-Moriya interaction(DMI),magnetocrystalline anisotropy,Ruderman-Kittel-Kasuya-Yosida(RKKY)interaction and four-spin interaction so as to trigger the generation of skyrmions and other topological spin structures.The materials covered include typical B20 crystals,various layered systems with interfacial DMI,frustrated materials,antiferromagnets,ferrimagnets,twodimensional(2D)materials,etc.In addition,the rare-earth(RE)permanent magnets can provide an energy barrier and enrich the dynamic behaviors of skyrmions,which has also been reviewed.
