Summary of main observation and conclusion Outstanding accomplishments have been achieved in the chemistry of difluorocarbene,but transitionmetal-catalyzed transfer of difluorocarbene for coupling remains a challengin...Summary of main observation and conclusion Outstanding accomplishments have been achieved in the chemistry of difluorocarbene,but transitionmetal-catalyzed transfer of difluorocarbene for coupling remains a challenging task.Herein,we describe a Pd-catalyzed coupling of difluorocarbene with two aryl carbon centers to give difluoromethylenation products,which cannot be obtained by any previous difluorocarbene-transformation method.展开更多
基金We thank the National Natural Science Foundation of China(Nos.21421002,21672242,21971252,21991122)Key ResearchProgram of Frontier Sciences,Chinese Academy of Sciences(CAS)(QYZDISSW-SLH049)and Youth Innovation Promotion Associa-tion CAS(2019256)for tinancial support.
文摘Summary of main observation and conclusion Outstanding accomplishments have been achieved in the chemistry of difluorocarbene,but transitionmetal-catalyzed transfer of difluorocarbene for coupling remains a challenging task.Herein,we describe a Pd-catalyzed coupling of difluorocarbene with two aryl carbon centers to give difluoromethylenation products,which cannot be obtained by any previous difluorocarbene-transformation method.
