Degradation of bisphenol A(BPA) in aqueous solution using sulfate radicals was investigated using the Fe(II)-activated peroxydisulfate(PDS) process, electrochemical process, electrochemical process with 2.5 mmol...Degradation of bisphenol A(BPA) in aqueous solution using sulfate radicals was investigated using the Fe(II)-activated peroxydisulfate(PDS) process, electrochemical process, electrochemical process with 2.5 mmol/L Na2S2O8 without Fe(II), and electrochemical assistant Fe(II)-activated PDS process. It was found that the electrochemical assistant Fe(II)-activated PDS process performed best in the degradation of BPA.The variables considered to influence the degradation efficiency of BPA were the initial concentration of Fe2 t, the initial concentration of Na2S2O8, and the current density. More than 97% of the BPA removals were achieved within 120 min under the optimum operational condition.The degradation of BPA was accompanied by the formation of phenol, hydroquinone, and small-molecule compounds such as succinic acid. The electron transfer was the principal step in the oxidation of BPA.展开更多
Objective:To investigate the effects of liraglutide combined with metformin on lipid metabolism and micro-inflammatory response in T2DM patients with obesity.Methods:A total of 138 T2DM patients with obesity who were ...Objective:To investigate the effects of liraglutide combined with metformin on lipid metabolism and micro-inflammatory response in T2DM patients with obesity.Methods:A total of 138 T2DM patients with obesity who were treated in the hospital between May 2016 and August 2017 were divided into control group (n=69) and liraglutide group (n=69) by random number table method. Control group received metformin therapy and liraglutide group received liraglutide combined with metformin therapy, which lasted for 3 months. The differences in the levels of insulin resistance indexes, cholesterol-related indexes, apolipoprotein and inflammatory mediators were compared between the two groups.Results:After 3 months of treatment, serum insulin resistance-related indexes FBG and FINS levels of liraglutide group were lower than those of control group;serum cholesterol-related indexes TC and LDL-C contents were lower than those of control group whereas HDL-C content was higher than that of control group;serum apolipoprotein Apo AⅠ and Apo AⅡ contents were higher than those of control group whereas Apo CⅡ and Apo CⅢ contents were lower than those of control group;serum inflammatory mediators IL-6, IL-17 and TNF-α contents were lower than those of control group.Conclusion:Metformin combined with liraglutide therapy can further optimize the glycolipid metabolism and inhibit the micro-inflammatory state in T2DM patients with obesity.展开更多
基金supported by the Natural Science Foundation of Jilin Province(Grant No.20140101215JC)the Key Program in Science and Technologies of Jilin Province(Grant No.20150204049SF)the Key Laboratory of Industrial Ecology and Environmental Engineering,the Ministry of Education of China(Grant No.KLIEEE-13-07)
文摘Degradation of bisphenol A(BPA) in aqueous solution using sulfate radicals was investigated using the Fe(II)-activated peroxydisulfate(PDS) process, electrochemical process, electrochemical process with 2.5 mmol/L Na2S2O8 without Fe(II), and electrochemical assistant Fe(II)-activated PDS process. It was found that the electrochemical assistant Fe(II)-activated PDS process performed best in the degradation of BPA.The variables considered to influence the degradation efficiency of BPA were the initial concentration of Fe2 t, the initial concentration of Na2S2O8, and the current density. More than 97% of the BPA removals were achieved within 120 min under the optimum operational condition.The degradation of BPA was accompanied by the formation of phenol, hydroquinone, and small-molecule compounds such as succinic acid. The electron transfer was the principal step in the oxidation of BPA.
文摘Objective:To investigate the effects of liraglutide combined with metformin on lipid metabolism and micro-inflammatory response in T2DM patients with obesity.Methods:A total of 138 T2DM patients with obesity who were treated in the hospital between May 2016 and August 2017 were divided into control group (n=69) and liraglutide group (n=69) by random number table method. Control group received metformin therapy and liraglutide group received liraglutide combined with metformin therapy, which lasted for 3 months. The differences in the levels of insulin resistance indexes, cholesterol-related indexes, apolipoprotein and inflammatory mediators were compared between the two groups.Results:After 3 months of treatment, serum insulin resistance-related indexes FBG and FINS levels of liraglutide group were lower than those of control group;serum cholesterol-related indexes TC and LDL-C contents were lower than those of control group whereas HDL-C content was higher than that of control group;serum apolipoprotein Apo AⅠ and Apo AⅡ contents were higher than those of control group whereas Apo CⅡ and Apo CⅢ contents were lower than those of control group;serum inflammatory mediators IL-6, IL-17 and TNF-α contents were lower than those of control group.Conclusion:Metformin combined with liraglutide therapy can further optimize the glycolipid metabolism and inhibit the micro-inflammatory state in T2DM patients with obesity.