A parameterized dynamics analysis model of legged lander with adaptive landing gear was established. Based on the analysis model, the landing performances under various landing conditions were analyzed by the optimize...A parameterized dynamics analysis model of legged lander with adaptive landing gear was established. Based on the analysis model, the landing performances under various landing conditions were analyzed by the optimized Latin hypercube experimental design method. In order to improve the landing performances, a hierarchical optimization method was proposed considering the uncertainty of landing conditions. The optimization problem was divided into a higher level(hereafter the "leader") and several lower levels(hereafter the "follower"). The followers took condition?ing factors as design variables to find out the worst landing conditions, while the leader took bu er parameters as design variables to better the landing performance under worst conditions. First of all, sensitivity analysis of landing conditioning factors was carried out according to the results of experimental design. After the sensitive factors were screened out, the response surface models were established to reflect the complicated relationships between sensi?tive conditioning factors, bu er parameters and landing performance indexes. Finally, the response surface model was used for hierarchical optimization iteration to improve the computational e ciency. After selecting the optimum bu er parameters from the solution set, the dynamic model with the optimum parameters was simulated again under the same landing conditions as the simulation before. After optimization, nozzle performance against damage is improved by 5.24%, the acceleration overload is reduced by 5.74%, and the primary strut improves its performance by 21.10%.展开更多
In this paper, we introduce some new classes of the totally quasi-G-asymptotically nonexpansive mappings and the totally quasi-G-asymptotically nonexpansive semigroups. Then, with the generalized f-projection operator...In this paper, we introduce some new classes of the totally quasi-G-asymptotically nonexpansive mappings and the totally quasi-G-asymptotically nonexpansive semigroups. Then, with the generalized f-projection operator, we prove some strong convergence theorems of a new modified Halpern type hybrid iterative algorithm for the totally quasi-G-asymptotically nonexpansive semigroups in Banach space. The results presented in this paper extend and improve some corresponding ones by many others.展开更多
A survey was conducted of the volatile organic compounds(VOCs)released from sources of solvent use,industry activities and vehicle emissions in Guiyang,a capital city of China.Samples were collected by canisters and a...A survey was conducted of the volatile organic compounds(VOCs)released from sources of solvent use,industry activities and vehicle emissions in Guiyang,a capital city of China.Samples were collected by canisters and analyzed by GC-MS-FID.The species profiles of VOCs emitted from sources were obtained.Results showed that xylenes,ethylbenzene,acetone and dichloromethane were the characteristics species for painting,2-propanol and ethyl acetate for printing,α-pinene for solid wood furniture manufacturing,and 2-butanone for biscuit baking.These characteristics species could be as tracers for the sources respectively.In most of samples from the solvent use,the benzene/toluene(B/T)ratio was less than 0.3,indicating that the ratio could be as the indicator for tracing the solvent use related sources.The results also suggested that the toluene/xylene(T/X)ratio be as the indicator to distinguish the VOCs sources of painting(<2)from the printing(>2).Aromatics contributed the most to ozone formation potential(OFP)of most painting and non-paper printing sources,and oxygen-containing VOCs(OVOCs)were major species contributing to OFP of the sources from food production and paper printing.The OFP of the VOCs emissions from vehicle in tunnels and from other manufactures were dominated by both aromatics and alkenes.Theα-pinene could explain 56.94%and 32.54%of total OFP of the VOCs sources from filing cabinet and solid wood furniture manufacturing,which was rarely been involved in previous studies of VOCs source profiles,indicating that the species of concern for VOCs sources are still insufficient at present.展开更多
Photodynamic therapy is a noninvasive type of phototherapy with a high capacity to boost specific antitumor immunity by causing immunogenic cell death.However,the photodynamic therapeutic potency toward solid tumors i...Photodynamic therapy is a noninvasive type of phototherapy with a high capacity to boost specific antitumor immunity by causing immunogenic cell death.However,the photodynamic therapeutic potency toward solid tumors is dampened by tumor hypoxia that negatively impairs the generation of cytotoxic singlet oxygen and promotes the formation of tumor immunosuppression.Herein,fluorinated CaCO_(3)(CaF)nanoparticles are prepared with the addition of dopamine-conjugated perfluorosebacic acid and ferric chloride into a calcium chloride ethanol solution via an ammonium bicarbonate-mediated gas-diffusion process.After being coated with commercial lipids and hexadecylamin conjugated chlorin e6(hCe6)via a templated self-assembly process,the yielded PEGylated nanophotosensitizer(hCe6@CaF-PEG)exhibits an effective loading efficiency to perfluoro-15-crown-5-ether(PFCE),a model perfluorocarbon molecule,and thus oxygen molecules.Upon intravenous administration,the obtained PFCE/hCe6@CaF-PEG can alleviate tumor hypoxia by working as an oxygen nanoshuttle.Together with local light emitting diode light exposure,photodynamic treatment with PFCE/hCe6@CaF-PEG can suppress the growth of primary CT26 tumors and unirradiated distant tumors,particularly when synergized with anti-PD-1(aPD-1)immunotherapy to collectively reverse tumor immunosuppression.This work presents an effective strategy to potentiate photodynamic immunotherapy by concurrently reversing tumor hypoxia and immunosuppression.展开更多
On-road driving emissions of six liquefied natural gas(LNG) and diesel semi-trailer towing vehicles(STTVs) which met China Emission Standard IV and V were tested using Portable Emission Measurement System(PEMS) in nor...On-road driving emissions of six liquefied natural gas(LNG) and diesel semi-trailer towing vehicles(STTVs) which met China Emission Standard IV and V were tested using Portable Emission Measurement System(PEMS) in northern China.Emission characteristics of these vehicles under real driving conditions were analyzed and proved that on-road emissions of heavy-duty vehicles(HDVs) were underestimated in the past.There were large differences among LNG and diesel vehicles, which also existed between China V vehicles and China IV vehicles.Emission factors showed the highest level under real driving conditions, which probably be caused by frequent acceleration, deceleration, and start-stop.NOx emission factors ranged from 2.855 to 20.939 g/km based on distance-traveled and 6.719–90.557 g/kg based on fuel consumption during whole tests, which were much higher than previous researches on chassis dynamometer.It was inferred from tests that the fuel consumption rate of the test vehicles had a strong correlation with NOx emission, and the exhaust temperature also affected the efficiency of Selected Catalytic Reduction(SCR) aftertreatment system, thus changing the NOx emission greatly.THC emission factors of LNG vehicles were 2.012–10.636 g/km, which were much higher than that of diesel vehicles(0.029–0.185 g/km).Unburned CH4 may be an important reason for this phenomenon.Further on-road emission tests, especially CH4 emission test should be carried out in subsequent research.In addition, the Particulate Number(PN) emission factors of diesel vehicles were at a very high level during whole tests, and Diesel Particulate Filter(DPF)should be installed to reduce PN emission.展开更多
Titanium dioxide nanoparticles(TiO_2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause d...Titanium dioxide nanoparticles(TiO_2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO_2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This review summarizes the toxic effects of TiO_2 NPs on multiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO_2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species(ROS)produced by TiO_2 NPs following the induction of electron–hole pairs; cell wall damage and lipid peroxidation of the cell membrane caused by NP-cell attachment by electrostatic force owing to the large surface area of TiO_2 NPs; and TiO_2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes.展开更多
Safe soft landing of the lander is vital to the Mars surface exploration mission. Analysis and verification of the landing stability under uncertain terrain play an important role in lander design. However, the effect...Safe soft landing of the lander is vital to the Mars surface exploration mission. Analysis and verification of the landing stability under uncertain terrain play an important role in lander design. However, the effect of uncertain terrain is ignored in most existing studies, making the analysis incomprehensive and increasing the risk of landing failure in practice. In this paper, a Mars lander with 10 attitude control thrusters is introduced and its dynamics model is then established considering plastic deformation parts and nonlinear contact forces. The effectiveness and accuracy of the dynamics modeling method are verified by experiments with an average relative error of 10%.In order to carry out the dynamics simulation with high-fidelity terrain, a terrain generation method based on statistical data is proposed. Through Monte Carlo simulation under a 50 m × 50 m randomly generated landing terrain, the stability of the lander and the effects of attitude control thrusters are analyzed. The results show that the failure rate is 5.5%, in which the primary failure forms are overturning and abnormal attitude. When the landing simulations are repeated without thrusters, the stable ratio decreases from 94.5% to 90.7%, suggesting the positive effects of attitude control thrusters in improving landing stability under rough terrain.展开更多
Although numerous studies on heavy metals(HMs)in sediments have been carried out in the East China Sea(ECS),the knowledge on the recent pollution levels of HMs in coastal region remains not well understood due to the ...Although numerous studies on heavy metals(HMs)in sediments have been carried out in the East China Sea(ECS),the knowledge on the recent pollution levels of HMs in coastal region remains not well understood due to the rapid developments of urbanization in eastern China.In this study,23 surface samples and 4 core samples are collected in the inner shelf of the ECS.The average dry-weight concentrations follow the descending order of Zn,Cr,Ni,Pb,Cu,As,Cd,and Hg(103.6±26.0,42.8±12.4,37.0±9.1,34.7±11.1,19.5±10.3,15.7±11.6,0.056±0.017,and 0.041±0.017μg g^(−1),respectively).HMs concentrations share a similar spatial distribution pattern of TOC content with a decreasing trend from coastline to outer sea.Additionally,HMs concentrations exhibit a decreasing trend from top to bottom sediments,especially for Hg at the open sites due to the wet and dry deposition of atmospheric Hg besides the riverine inputs.The potential ecological risk indices(PERI)values in coastal sediments were about 2-4 times higher than those in open sea.Although the Hg and Cd concentrations were lower by 2-3 orders of magnitude than those of other six metals,the PERI values of Hg(65.5)and Cd(52.1)were 3-40 times higher than those of others.The hierarchical cluster result is consistent with the PCA result,suggesting that Hg,Cd,and As have similar sources and probably mainly originated from anthropogenic emissions.展开更多
Mercury fate of sewage irrigation in farmlands deserves attention with increasing scarcity of freshwater resources for agriculture in the worldwide.Soil-air total gaseous mercury(TGM)fluxes from four-sewage and one-fr...Mercury fate of sewage irrigation in farmlands deserves attention with increasing scarcity of freshwater resources for agriculture in the worldwide.Soil-air total gaseous mercury(TGM)fluxes from four-sewage and one-fresh water irrigated farmlands were determined simultaneously.During maize-wheat rotation,soil-air TGM fluxes showed patterns of both emission and deposition during different growth stages.It enhanced one-order of magnitude emission with increased Hg contamination from historical sewage irrigation.A linear response relationship of TGM fluxes with soil Hg concentration was found,which showed greater TGM emission potential comparing with those from forest and urban soils.However,the ratio of soil-air TGM flux in daytime to nighttime were 3.94 in maize-season and 3.41 in wheat-season,respectively,which were little related to the change in soil Hg concentration.Furthermore,soil temperature and moisture,ambient-air TGM concentration all effected TGM evasion from sewage-irrigated soils.The data presented here suggest that evasion of TGMfromhistorical sewage irrigation farmlands with high Hg concentrations may be potential hotspots for Hg emission in atmosphere,and it was likely to underestimate Hg emissions from farmlands in existing emissions inventory.Additional regionalinvestigations and process-level researches are needed to better understand role of sewage irrigation farmlands in local-global Hg-biogeochemical-cycles.展开更多
基金Supported by National Natural Science Foundation of China(Grant No.51635002)
文摘A parameterized dynamics analysis model of legged lander with adaptive landing gear was established. Based on the analysis model, the landing performances under various landing conditions were analyzed by the optimized Latin hypercube experimental design method. In order to improve the landing performances, a hierarchical optimization method was proposed considering the uncertainty of landing conditions. The optimization problem was divided into a higher level(hereafter the "leader") and several lower levels(hereafter the "follower"). The followers took condition?ing factors as design variables to find out the worst landing conditions, while the leader took bu er parameters as design variables to better the landing performance under worst conditions. First of all, sensitivity analysis of landing conditioning factors was carried out according to the results of experimental design. After the sensitive factors were screened out, the response surface models were established to reflect the complicated relationships between sensi?tive conditioning factors, bu er parameters and landing performance indexes. Finally, the response surface model was used for hierarchical optimization iteration to improve the computational e ciency. After selecting the optimum bu er parameters from the solution set, the dynamic model with the optimum parameters was simulated again under the same landing conditions as the simulation before. After optimization, nozzle performance against damage is improved by 5.24%, the acceleration overload is reduced by 5.74%, and the primary strut improves its performance by 21.10%.
文摘In this paper, we introduce some new classes of the totally quasi-G-asymptotically nonexpansive mappings and the totally quasi-G-asymptotically nonexpansive semigroups. Then, with the generalized f-projection operator, we prove some strong convergence theorems of a new modified Halpern type hybrid iterative algorithm for the totally quasi-G-asymptotically nonexpansive semigroups in Banach space. The results presented in this paper extend and improve some corresponding ones by many others.
基金the Guiyang Research Academy of Eco-Environmental Science for partial support of this project。
文摘A survey was conducted of the volatile organic compounds(VOCs)released from sources of solvent use,industry activities and vehicle emissions in Guiyang,a capital city of China.Samples were collected by canisters and analyzed by GC-MS-FID.The species profiles of VOCs emitted from sources were obtained.Results showed that xylenes,ethylbenzene,acetone and dichloromethane were the characteristics species for painting,2-propanol and ethyl acetate for printing,α-pinene for solid wood furniture manufacturing,and 2-butanone for biscuit baking.These characteristics species could be as tracers for the sources respectively.In most of samples from the solvent use,the benzene/toluene(B/T)ratio was less than 0.3,indicating that the ratio could be as the indicator for tracing the solvent use related sources.The results also suggested that the toluene/xylene(T/X)ratio be as the indicator to distinguish the VOCs sources of painting(<2)from the printing(>2).Aromatics contributed the most to ozone formation potential(OFP)of most painting and non-paper printing sources,and oxygen-containing VOCs(OVOCs)were major species contributing to OFP of the sources from food production and paper printing.The OFP of the VOCs emissions from vehicle in tunnels and from other manufactures were dominated by both aromatics and alkenes.Theα-pinene could explain 56.94%and 32.54%of total OFP of the VOCs sources from filing cabinet and solid wood furniture manufacturing,which was rarely been involved in previous studies of VOCs source profiles,indicating that the species of concern for VOCs sources are still insufficient at present.
基金This work was partially supported by the National Natural Science Foundation of China(No.22077093)the National Research Programs from Ministry of Science and Technology(MOST)of China(Nos.2021YFF0701800 and 2022YFF0706500)+1 种基金the Natural Science Foundation of Jiangsu Province(No.BK20220110)the Collaborative Innovation Center of Suzhou Nano Science and Technology,the Suzhou Key Laboratory of Nanotechnology and Biomedicine,and the 111 Program from the Ministry of Education of China。
文摘Photodynamic therapy is a noninvasive type of phototherapy with a high capacity to boost specific antitumor immunity by causing immunogenic cell death.However,the photodynamic therapeutic potency toward solid tumors is dampened by tumor hypoxia that negatively impairs the generation of cytotoxic singlet oxygen and promotes the formation of tumor immunosuppression.Herein,fluorinated CaCO_(3)(CaF)nanoparticles are prepared with the addition of dopamine-conjugated perfluorosebacic acid and ferric chloride into a calcium chloride ethanol solution via an ammonium bicarbonate-mediated gas-diffusion process.After being coated with commercial lipids and hexadecylamin conjugated chlorin e6(hCe6)via a templated self-assembly process,the yielded PEGylated nanophotosensitizer(hCe6@CaF-PEG)exhibits an effective loading efficiency to perfluoro-15-crown-5-ether(PFCE),a model perfluorocarbon molecule,and thus oxygen molecules.Upon intravenous administration,the obtained PFCE/hCe6@CaF-PEG can alleviate tumor hypoxia by working as an oxygen nanoshuttle.Together with local light emitting diode light exposure,photodynamic treatment with PFCE/hCe6@CaF-PEG can suppress the growth of primary CT26 tumors and unirradiated distant tumors,particularly when synergized with anti-PD-1(aPD-1)immunotherapy to collectively reverse tumor immunosuppression.This work presents an effective strategy to potentiate photodynamic immunotherapy by concurrently reversing tumor hypoxia and immunosuppression.
基金supported by the National Key Research and Development Program of China(No.2016YFC0208005)the Open Research Program of State Key Laboratory of Engine Combustion(No.K2018-11).
文摘On-road driving emissions of six liquefied natural gas(LNG) and diesel semi-trailer towing vehicles(STTVs) which met China Emission Standard IV and V were tested using Portable Emission Measurement System(PEMS) in northern China.Emission characteristics of these vehicles under real driving conditions were analyzed and proved that on-road emissions of heavy-duty vehicles(HDVs) were underestimated in the past.There were large differences among LNG and diesel vehicles, which also existed between China V vehicles and China IV vehicles.Emission factors showed the highest level under real driving conditions, which probably be caused by frequent acceleration, deceleration, and start-stop.NOx emission factors ranged from 2.855 to 20.939 g/km based on distance-traveled and 6.719–90.557 g/kg based on fuel consumption during whole tests, which were much higher than previous researches on chassis dynamometer.It was inferred from tests that the fuel consumption rate of the test vehicles had a strong correlation with NOx emission, and the exhaust temperature also affected the efficiency of Selected Catalytic Reduction(SCR) aftertreatment system, thus changing the NOx emission greatly.THC emission factors of LNG vehicles were 2.012–10.636 g/km, which were much higher than that of diesel vehicles(0.029–0.185 g/km).Unburned CH4 may be an important reason for this phenomenon.Further on-road emission tests, especially CH4 emission test should be carried out in subsequent research.In addition, the Particulate Number(PN) emission factors of diesel vehicles were at a very high level during whole tests, and Diesel Particulate Filter(DPF)should be installed to reduce PN emission.
基金supported by the National Natural Science Foundation of China (Nos.21607043,21577032)the Youth Innovation Promotion Association,Chinese Academy of Sciences (No.2018054)+1 种基金the Fundamental Research Funds for the Central Universities (Nos.2016ZZD06,2018ZD11)the Open Project of Key Laboratory of Environmental Biotechnology,CAS (No.kf2016009)
文摘Titanium dioxide nanoparticles(TiO_2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO_2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This review summarizes the toxic effects of TiO_2 NPs on multiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO_2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species(ROS)produced by TiO_2 NPs following the induction of electron–hole pairs; cell wall damage and lipid peroxidation of the cell membrane caused by NP-cell attachment by electrostatic force owing to the large surface area of TiO_2 NPs; and TiO_2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes.
基金supported by the Joint Fund of Advanced Aerospace Manufacturing Technology Research(No.U2037602)。
文摘Safe soft landing of the lander is vital to the Mars surface exploration mission. Analysis and verification of the landing stability under uncertain terrain play an important role in lander design. However, the effect of uncertain terrain is ignored in most existing studies, making the analysis incomprehensive and increasing the risk of landing failure in practice. In this paper, a Mars lander with 10 attitude control thrusters is introduced and its dynamics model is then established considering plastic deformation parts and nonlinear contact forces. The effectiveness and accuracy of the dynamics modeling method are verified by experiments with an average relative error of 10%.In order to carry out the dynamics simulation with high-fidelity terrain, a terrain generation method based on statistical data is proposed. Through Monte Carlo simulation under a 50 m × 50 m randomly generated landing terrain, the stability of the lander and the effects of attitude control thrusters are analyzed. The results show that the failure rate is 5.5%, in which the primary failure forms are overturning and abnormal attitude. When the landing simulations are repeated without thrusters, the stable ratio decreases from 94.5% to 90.7%, suggesting the positive effects of attitude control thrusters in improving landing stability under rough terrain.
基金This work was supported by the National Key Research and Development Program of China[2017YFC0505702]the National Natural Science Foundation of China[41176066,41807345].
文摘Although numerous studies on heavy metals(HMs)in sediments have been carried out in the East China Sea(ECS),the knowledge on the recent pollution levels of HMs in coastal region remains not well understood due to the rapid developments of urbanization in eastern China.In this study,23 surface samples and 4 core samples are collected in the inner shelf of the ECS.The average dry-weight concentrations follow the descending order of Zn,Cr,Ni,Pb,Cu,As,Cd,and Hg(103.6±26.0,42.8±12.4,37.0±9.1,34.7±11.1,19.5±10.3,15.7±11.6,0.056±0.017,and 0.041±0.017μg g^(−1),respectively).HMs concentrations share a similar spatial distribution pattern of TOC content with a decreasing trend from coastline to outer sea.Additionally,HMs concentrations exhibit a decreasing trend from top to bottom sediments,especially for Hg at the open sites due to the wet and dry deposition of atmospheric Hg besides the riverine inputs.The potential ecological risk indices(PERI)values in coastal sediments were about 2-4 times higher than those in open sea.Although the Hg and Cd concentrations were lower by 2-3 orders of magnitude than those of other six metals,the PERI values of Hg(65.5)and Cd(52.1)were 3-40 times higher than those of others.The hierarchical cluster result is consistent with the PCA result,suggesting that Hg,Cd,and As have similar sources and probably mainly originated from anthropogenic emissions.
基金This work was supported by the National Natural Science Foundation of China[41371461]National Key Research and Development Program of China[2017YFC0210106].
文摘Mercury fate of sewage irrigation in farmlands deserves attention with increasing scarcity of freshwater resources for agriculture in the worldwide.Soil-air total gaseous mercury(TGM)fluxes from four-sewage and one-fresh water irrigated farmlands were determined simultaneously.During maize-wheat rotation,soil-air TGM fluxes showed patterns of both emission and deposition during different growth stages.It enhanced one-order of magnitude emission with increased Hg contamination from historical sewage irrigation.A linear response relationship of TGM fluxes with soil Hg concentration was found,which showed greater TGM emission potential comparing with those from forest and urban soils.However,the ratio of soil-air TGM flux in daytime to nighttime were 3.94 in maize-season and 3.41 in wheat-season,respectively,which were little related to the change in soil Hg concentration.Furthermore,soil temperature and moisture,ambient-air TGM concentration all effected TGM evasion from sewage-irrigated soils.The data presented here suggest that evasion of TGMfromhistorical sewage irrigation farmlands with high Hg concentrations may be potential hotspots for Hg emission in atmosphere,and it was likely to underestimate Hg emissions from farmlands in existing emissions inventory.Additional regionalinvestigations and process-level researches are needed to better understand role of sewage irrigation farmlands in local-global Hg-biogeochemical-cycles.