[Objectives] To investigate the clinical efficacy of intermittent levosimendan in the treatment of acute heart failure. [Methods] 100 patients diagnosed with acute heart failure and hospitalized in the internal medici...[Objectives] To investigate the clinical efficacy of intermittent levosimendan in the treatment of acute heart failure. [Methods] 100 patients diagnosed with acute heart failure and hospitalized in the internal medicine-cardiovascular department in The First People s Hospital of Yulin from January 2019 to February 2020 were randomly divided into two groups, 50 cases in each group. Both groups were treated with conventional anti-heart failure drugs. The control group was given levosimendan once, and the observation group was given levosimendan three times, with an interval of one month. The creatinine (Cr) level, serum NT proBNP, left ventricular ejection fraction (LVEF) and left ventricular end diastolic diameter (LVEDD) were observed at 48 h before and after treatment and one month and two months after treatment in both groups. [Results] Compared with before treatment, the levels of NT-proBNP decreased in the two groups at 48 h after treatment, and the difference was statistically significant ( P <0.05). The Cr level of the control group did not change significantly before and after treatment, and the Cr level of the observation group decreased at one and two months after treatment compared with before treatment, with statistically significant differences ( P <0.05). Compared with before treatment, NT-proBNP and LVEDD decreased and LVEF increased at one and two months after treatment, and the differences were statistically significant ( P <0.05). There were no obvious adverse reactions in the two groups of patients during the treatment. [Conclusions] Repetitive use of levosimendan in the treatment of acute heart failure could significantly improve the renal function, cardiac contractility and cardiac function of patients, and with the passage of time, the treatment effect was improved, which is worthy of clinical promotion.展开更多
An epidemic model which describes Huanglongbing transmission is proposed with the goal of investigating the effect of quarantine measures on the spread of diseases. First of all, the analytical formula for the basic r...An epidemic model which describes Huanglongbing transmission is proposed with the goal of investigating the effect of quarantine measures on the spread of diseases. First of all, the analytical formula for the basic reproduction number <em>R</em><sub>0</sub> is obtained by the means of next generation matrix, and the existence of disease-free equilibrium and endemic equilibrium is discussed. Then, the local stability and the global stability of equilibria are investigated by using Routh-Hurwitz criterion and Lyapunov function, respectively. Numerical simulations indicate that comprehensive quarantine measures can effectively control the spread of Huanglongbing. It provides a reliable tactic basis for preventing the epidemic outbreak.展开更多
Incorporating plant-dependent saturated reproduction function, chemical insecticide, and its resistance, a plant-vector-virus model which describes the spread of infection throughout the plant by the insect is investi...Incorporating plant-dependent saturated reproduction function, chemical insecticide, and its resistance, a plant-vector-virus model which describes the spread of infection throughout the plant by the insect is investigated in this paper. First of all, the basic reproduction number R<sub>0</sub> is obtained by using the method of the next generation matrix, and the existence of disease-free equilibrium and endemic equilibrium is examined. Then we show that the disease-free steady state is globally asymptotically stable if R<sub>0</sub> 1, the system is uniformly persistent and the endemic equilibrium is local stability. Finally, numerical simulation is carried out to illustrate our theoretical results. Our result implies that insecticide resistance has a vital impact on the control of plant diseases.展开更多
A mathematical model described the propagation of information including rumor and truth presented and its properties investigated. We explored exists of the equilibria, local stability and global asymptotical stabilit...A mathematical model described the propagation of information including rumor and truth presented and its properties investigated. We explored exists of the equilibria, local stability and global asymptotical stability, and obtained the propagation threshold of rumor spreading. Numerical simulation is shown to demonstrate our results. Uncertainty and sensitivity analysis shows the importance of the parameters in our model.展开更多
In this paper, the SECIR rumor spreading model is formulated and analyzed, in which the social education level and the counterattack mechanism are taken into consideration. The results show that improving education le...In this paper, the SECIR rumor spreading model is formulated and analyzed, in which the social education level and the counterattack mechanism are taken into consideration. The results show that improving education level and increasing the ratio of counter are effective in reducing the risk of rumor propagation and enhancing the resistance to rumor propagation.展开更多
We propose a multiscale projection method for the numerical solution of the irtatively regularized Gauss-Newton method of nonlinear integral equations.An a posteriori rule is suggested to choose the stopping index of ...We propose a multiscale projection method for the numerical solution of the irtatively regularized Gauss-Newton method of nonlinear integral equations.An a posteriori rule is suggested to choose the stopping index of iteration and the rates of convergence are also derived under the Lipschitz condition.Numerical results are presented to demonstrate the efficiency and accuracy of the proposed method.展开更多
基金Supported by Scientific Research and Technology Development Program of Yulin City(20204031).
文摘[Objectives] To investigate the clinical efficacy of intermittent levosimendan in the treatment of acute heart failure. [Methods] 100 patients diagnosed with acute heart failure and hospitalized in the internal medicine-cardiovascular department in The First People s Hospital of Yulin from January 2019 to February 2020 were randomly divided into two groups, 50 cases in each group. Both groups were treated with conventional anti-heart failure drugs. The control group was given levosimendan once, and the observation group was given levosimendan three times, with an interval of one month. The creatinine (Cr) level, serum NT proBNP, left ventricular ejection fraction (LVEF) and left ventricular end diastolic diameter (LVEDD) were observed at 48 h before and after treatment and one month and two months after treatment in both groups. [Results] Compared with before treatment, the levels of NT-proBNP decreased in the two groups at 48 h after treatment, and the difference was statistically significant ( P <0.05). The Cr level of the control group did not change significantly before and after treatment, and the Cr level of the observation group decreased at one and two months after treatment compared with before treatment, with statistically significant differences ( P <0.05). Compared with before treatment, NT-proBNP and LVEDD decreased and LVEF increased at one and two months after treatment, and the differences were statistically significant ( P <0.05). There were no obvious adverse reactions in the two groups of patients during the treatment. [Conclusions] Repetitive use of levosimendan in the treatment of acute heart failure could significantly improve the renal function, cardiac contractility and cardiac function of patients, and with the passage of time, the treatment effect was improved, which is worthy of clinical promotion.
文摘An epidemic model which describes Huanglongbing transmission is proposed with the goal of investigating the effect of quarantine measures on the spread of diseases. First of all, the analytical formula for the basic reproduction number <em>R</em><sub>0</sub> is obtained by the means of next generation matrix, and the existence of disease-free equilibrium and endemic equilibrium is discussed. Then, the local stability and the global stability of equilibria are investigated by using Routh-Hurwitz criterion and Lyapunov function, respectively. Numerical simulations indicate that comprehensive quarantine measures can effectively control the spread of Huanglongbing. It provides a reliable tactic basis for preventing the epidemic outbreak.
文摘Incorporating plant-dependent saturated reproduction function, chemical insecticide, and its resistance, a plant-vector-virus model which describes the spread of infection throughout the plant by the insect is investigated in this paper. First of all, the basic reproduction number R<sub>0</sub> is obtained by using the method of the next generation matrix, and the existence of disease-free equilibrium and endemic equilibrium is examined. Then we show that the disease-free steady state is globally asymptotically stable if R<sub>0</sub> 1, the system is uniformly persistent and the endemic equilibrium is local stability. Finally, numerical simulation is carried out to illustrate our theoretical results. Our result implies that insecticide resistance has a vital impact on the control of plant diseases.
文摘A mathematical model described the propagation of information including rumor and truth presented and its properties investigated. We explored exists of the equilibria, local stability and global asymptotical stability, and obtained the propagation threshold of rumor spreading. Numerical simulation is shown to demonstrate our results. Uncertainty and sensitivity analysis shows the importance of the parameters in our model.
文摘In this paper, the SECIR rumor spreading model is formulated and analyzed, in which the social education level and the counterattack mechanism are taken into consideration. The results show that improving education level and increasing the ratio of counter are effective in reducing the risk of rumor propagation and enhancing the resistance to rumor propagation.
基金Supported in part by the Natural Science Foundation of China under grants 11761010 and 61863001.
文摘We propose a multiscale projection method for the numerical solution of the irtatively regularized Gauss-Newton method of nonlinear integral equations.An a posteriori rule is suggested to choose the stopping index of iteration and the rates of convergence are also derived under the Lipschitz condition.Numerical results are presented to demonstrate the efficiency and accuracy of the proposed method.
