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Dynamic quasi-continuum model for plate-type nano-materials and analysis of fundamental frequency
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作者 chunxiao xia Wenlong XU Guohua NIE 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2021年第1期85-94,共10页
A dynamic quasi-continuum model is presented to analyze free vibration of plate-type cubic crystal nano-materials.According to the Hamilton principle,fundamental governing equations in terms of displacement components... A dynamic quasi-continuum model is presented to analyze free vibration of plate-type cubic crystal nano-materials.According to the Hamilton principle,fundamental governing equations in terms of displacement components and angles of rotations are given.As an application of the model,the cylindrical bending deformation of the structure fixed at two ends is analyzed,and a theoretical formula evaluating the fundamental frequency is obtained by using Galerkin's method.Meanwhile,the solution for the classical continuous plate model is also derived,and the size-dependent elastic modulus and Poisson's ratio are taken in computation.The frequencies corresponding to different atomic layers are numerically presented for the plate-type NaC l nano-materials.Furthermore,a molecular dynamics(MD)simulation is conducted with the code LAMMPS.The comparison shows that the present quasi-continuum model is valid,and it may be used as an alternative model,which reflects scale effects in analyzing dynamic behaviors of such plate-type nano-materials. 展开更多
关键词 plate-type nano-material quasi-continuum model SIZE-DEPENDENT fundamental frequency theoretical solution molecular dynamics(MD)simulation
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532nm眼底激光联合康柏西普对糖尿病视网膜病变患者VEGF和PEDF的影响 被引量:5
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作者 夏春晓 李凯敏 +3 位作者 都艳红 王艳新 贾冠美 刘晔青 《湖南师范大学学报(医学版)》 2022年第6期105-108,共4页
目的:研究532nm眼底激光联合康柏西普对糖尿病视网膜病变患者血管内皮生因子(vascular endothelial growth factor,VEGF)水平及色素上皮衍生因子(Pigment Epithelium-Derived Factor,PEDF)的影响.方法:选取2018年1月至2019年3月于我院... 目的:研究532nm眼底激光联合康柏西普对糖尿病视网膜病变患者血管内皮生因子(vascular endothelial growth factor,VEGF)水平及色素上皮衍生因子(Pigment Epithelium-Derived Factor,PEDF)的影响.方法:选取2018年1月至2019年3月于我院接受治疗的80例糖尿病视网膜病变的患者,按照数字表随机分组法分为观察组和对照组各40例.对照组患者采取康柏西普玻璃体腔注射治疗,观察组在对照组基础上联合使用532nm眼底激光.比较两组患者治疗前和治疗3个月后VEGF和PEDF水平、比较两组治疗前后视网膜厚度、视网膜血管瘤数量、渗漏面积及无灌注面积,并观察不良反应发生情况.结果:治疗后,两组VEGF增高而PEDF降低,且观察组VEGF低于对照组,PEDF高于对照组(P<0.05).治疗后两组视网膜厚度较治疗前降低,而观察组低于对照组(P<0.05).治疗后观察组血管瘤数量、渗漏面积显著低于对照组(P<0.05).两组不良反应无显著差异.结论:532nm眼底激光联合康柏西普治疗糖尿病视网膜病变可有效抑制视网膜新生血管生成,临床疗效好,安全性好,值得临床推广. 展开更多
关键词 糖尿病视网膜病变 532nm眼底激光治疗 康柏西普 血管内皮生因子
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