Acinetobacter baumannii is a frequent cause of nosocomial infections.Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A.baumannii(CRAB)clone ST457 and assess the effectiveness of pat...Acinetobacter baumannii is a frequent cause of nosocomial infections.Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A.baumannii(CRAB)clone ST457 and assess the effectiveness of patient screening for outbreak control.CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019.Fourteen CRAB isolates were assigned to ST457,and 13 belonged to an outbreak clone,as determined by phylogenomic analysis.Strict patient screening was started at the respiratory intensive care unit on May 2019,through which a ST457-positive patient transferred from the intensive care unit was detected.No positive patients were detected within 3months onwards.The results of this study highlight the importance of rigorous infection prevention and control measures,combined with patient screening,in controlling the CRAB outbreak.展开更多
基金This work was supported by the National Key Research and Development Program of China(2017YFC1200200)Major Infectious Diseases Such as AIDS and Viral Hepatitis Prevention and Control Technology Major Projects(2018ZX10712-001)+2 种基金the National Natural Science Foundation of China(81902030)Shenzhen Basic Research Key projects(JCYJ20200109144220704)Shenzhen Basic Research projects(JCYJ20190807144409307).
文摘Acinetobacter baumannii is a frequent cause of nosocomial infections.Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A.baumannii(CRAB)clone ST457 and assess the effectiveness of patient screening for outbreak control.CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019.Fourteen CRAB isolates were assigned to ST457,and 13 belonged to an outbreak clone,as determined by phylogenomic analysis.Strict patient screening was started at the respiratory intensive care unit on May 2019,through which a ST457-positive patient transferred from the intensive care unit was detected.No positive patients were detected within 3months onwards.The results of this study highlight the importance of rigorous infection prevention and control measures,combined with patient screening,in controlling the CRAB outbreak.
