心理疾病与心血管病学综述

近年来,循环系统疾病的死亡率一直居世界首位。全世界每年约有1740万人死于心血管疾病。在所有心血管疾病中,缺血性心脏病和动脉高血压及其并发症(心肌梗塞和中风)占很大比例。关于心身医学,文献中有两种截然不同的观点。一些人认为,许多健康问题都是由精神问题引起的,而另一些人则坚信,任何负面情绪都不可能成为人体躯体疾病的原因。在心身疾病中,心血管疾病被认为是最常见的。这些疾病多发于经常处于紧张和消极情绪中的人。心身疾病主要包括缺血性心脏病、心脏恐惧神经症、原发性高血压和心律失常。

Erratum:Development of a Spin-Exchange Optical Pumping-Based Polarized 3He System at the China Spallation Neutron Source(CSNS)[Chin.Phys.Lett.38,092801(2021)]

In our published paper,国an important affiliation(University of Chinese Academy of Sciences,Beijing 100049,China)should be added as the 3rd affiliation for the first author,as given above.References[1]Huang C,ZhangJ,Ye F,Qin Z,Amir S M,Buck Z N,Salman A,Kreuzpaintner W,Qi X,Wang T,and Tong X 2021 Chin.Phys.Lett.38092801。

Development of a Spin-Exchange Optical Pumping-Based Polarized ^(3)He System at the China Spallation Neutron Source (CSNS)

Polarized 3He neutron spin filters(NSFs)can be used as a vital tool for neutron polarization production and analysis.The China Spallation Neutron Source(CSNS),as one of the major neutron facilities in China,has committed resources to the development of a polarized ^(3)He NSF program to support its growing polarized neutron research.A spin-exchange optical pumping(SEOP)-based polarized ^(3)He system and other necessary hardware for NSF transport has been recently developed.The performance of the system is benchmarked using an in-house developed cell named“Trident”.Neutron beam measurements yield a ^(3)He polarization of 77%with over 200 h of on-beam relaxation time.Combining this newly developed SEOP system with the recently reported cell fabrication station,CSNS is now capable of the fully self-sustained production of ^(3)He NSFs that shall support its future neutron polarization research.

Development of Time-of-Flight Polarized Neutron Imaging at the China Spallation Neutron Source

A time-of-flight polarized neutron imaging setup was realized by integrating an in situ pumped polarized ^(3)He spin filter and energy dispersive neutron camera on the neutron technique development beamline(BL-20)of the China Spallation Neutron Source(CSNS).Test experiments were performed with a solenoid with aluminum wire as a sample.These demonstrated that polarized radiography with a field of view in diameter 2.0 cm at different wavelengths can be obtained.The wavelength-dependent polarization was used to distinguish the neutron polarization behavior for different positions inside and outside the solenoid.The results of this work show the possibility of applying the technique at CSNS and marks a milestone for future polarized neutron imaging developments.

Development of a ~3He Gas Filling Station at the China Spallation Neutron Source

At the China Spallation Neutron Source(CSNS), we have developed a custom gas-filling station, a glassblowing workshop, and a spin-exchange optical pumping(SEOP) system for producing high-quality ^(3)He-based neutron spin filter(NSF) cells. The gas-filling station is capable of routinely filling ^(3)He cells made from GE180 glass of various dimensions, to be used as neutron polarizers and analyzers on beamlines at the CSNS. Performance tests on cells fabricated at our gas-filling station are conducted via neutron transmission and nuclear-magneticresonance measurements, revealing nominal filling pressures, and a saturated ~3He polarization in the region of 80%, with a lifetime of approximately 240 hours. These results demonstrate our ability to produce competitive NSF cells to meet the ever-increasing research needs of the polarized neutron research community.

Relationship Between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood-brain Barrier Disruption in Mice and Its Possible Mechanism:Role of Aquaporin-4 and Connexin43

We aimed to select an optimized hematoma expansion(HE)model and investigate the possible mechanism of blood-brain barrier(BBB)damage in mice.The results showed that HE occurred in the group with hypertension combined with hyperglycemia(HH-HE)from3 to 72 h after intracerebral hemorrhage;this was accompanied by neurological deficits and hardly influenced the survival rate.The receiver operating characteristic curve suggested the criterion for this model was hematoma volume expansion≥45.0%.Meanwhile,HH-HE aggravated BBB disruption.A protector of the BBB reduced HH-HE,while a BBB disruptor induced a further HH-HE.Aquaporin-4(AQP4)knock-out led to larger hematoma volume and more severe BBB disruption.Furthermore,hematoma volume and BBB disruption were reduced by multiple connexin43(Cx43)inhibitors in the wild-type group but not in the AQP4 knock-out group.In conclusion,the optimized HE model is induced by hypertension and hyperglycemia with the criterion of hematoma volume expanding≥45.0%.HH-HE leads to BBB disruption,which is dependent on AQP4 and Cx43.

Sorption of aromatic organophosphate flame thermally and hydrothermally produced retardants on biochars

Aromatic organophosphate flame retardant(OPFR)pollutants and biochars are commonly present and continually released into soils due to their increasingly wide applications.In this study,for the first time,the sorption of OPFRs on biochars was investigated.Although triphenyl phosphate(TPhP)and triphenylphosphine oxide(TPPO)have similar molecular structures and sizes,TPhP exhibited much faster and higher sorption than TPPO due to its stronger hydrophobicity,suggesting the dominant role of hydrophobic interactions in TPhP sorption.Theπ-πelectron donor-acceptor(EDA)interactions also contributed to the sorption process,as suggested by the negative correlation between the sorption capacity of the aromatic OPFRs and the aromatic index(H/C atomic ratios)of biochar.Density functional theory calculations further showed that one benzene ring of aromatic OPFRs has no electrons,which may interact with biochar viaπ-πEDA interactions.The electrostatic attraction between the protonated P=O in OPFRs and the negatively charged biochar was found to occur at pH below 7.This work provides insights into the sorption behaviors and mechanisms of aromatic OPFRs by biochars.

In-situ optical pumping for polarizing 3He neutron spin filters at the China Spallation Neutron Source

In this paper,we present the performance of a recently developed in-situ spin-exchange optically pumped^(3)He-neutron spin filter system at the China Spallation Neutron Source(CSNS).The system achieved a^(3)He polarization of over 74%at the beamline BL-20.Analysis of neutron transmission experiment results reveals a neutron polarization of>90%and an average transmission of 27%for 2.2Åneutrons,which were maintained for a duration of 120 h of beam time.To the best of our knowledge,this is the first in-situ hyperpolarized^(3)He system incorporated on a neutron beamline in China.This technology is expected to provide stable,wide-angle,and highly polarized neutrons at the CSNS for materials research and fundamental neutron physics.