Prebiotic-like effects of maltitol were investigated supplementing two groups of rats with either 5% maltodextrin (control group) or 5% maltitol (maltitol group). A third group was supplemented with 5% maltitol at fir...Prebiotic-like effects of maltitol were investigated supplementing two groups of rats with either 5% maltodextrin (control group) or 5% maltitol (maltitol group). A third group was supplemented with 5% maltitol at first and then with 5% maltodextrin (maltitol/maltodextrin group). Faecal parameters were monitored throughout the experiment and caecal parameters at the end. The weights of caecal content and caecal wall were significantly higher in the maltitol group than in the control group, but not in the maltitol/maltodextrin group. Propionic acid concentration was significantly higher in the maltitol group compared to both control and maltitol/maltodextrin group. Faecal parameters were also influenced by the dietary supplementation with maltitol: the amount of dry matter in feces decreased and alpha-glucosidase activity increased. These effects lasted 28 days in the maltitol only group, whereas they stopped some days after the switch to maltodextrin in the maltitol/maltodextrin group. Maltitol could induce prebiotic-like effects.展开更多
Constipation is an area of concern in people’s health. Consequently, health care practitioners recommend lifestyle changes including increasing fiber intake and exercise. This study examined the effect of pea hull fi...Constipation is an area of concern in people’s health. Consequently, health care practitioners recommend lifestyle changes including increasing fiber intake and exercise. This study examined the effect of pea hull fiber (PHF) on loperamide-induced constipation in rats. The rats were fed either a vehicle diet or a diet enriched with PHF. The groups were divided into either a saline or loperamide injection to induce sub-acute constipation. Fecal Pellet Output (FPO) was measured for 3 days. In the saline-treated rats, PHF increased wet and dry fecal weights on day 1 and 2, and increased FPO on day 2 compared to the saline-treated rats on the vehicle diet. In the loperamide model, PHF <span>increased FPO, had higher wet and dry fecal weights on day 1 compared </span><span>to the loperamide-treated vehicle diet rats. Addition of PHF into the diet ma</span>y help improve intestinal transit in a loperamide-induced constipation rat model.展开更多
文摘Prebiotic-like effects of maltitol were investigated supplementing two groups of rats with either 5% maltodextrin (control group) or 5% maltitol (maltitol group). A third group was supplemented with 5% maltitol at first and then with 5% maltodextrin (maltitol/maltodextrin group). Faecal parameters were monitored throughout the experiment and caecal parameters at the end. The weights of caecal content and caecal wall were significantly higher in the maltitol group than in the control group, but not in the maltitol/maltodextrin group. Propionic acid concentration was significantly higher in the maltitol group compared to both control and maltitol/maltodextrin group. Faecal parameters were also influenced by the dietary supplementation with maltitol: the amount of dry matter in feces decreased and alpha-glucosidase activity increased. These effects lasted 28 days in the maltitol only group, whereas they stopped some days after the switch to maltodextrin in the maltitol/maltodextrin group. Maltitol could induce prebiotic-like effects.
文摘Constipation is an area of concern in people’s health. Consequently, health care practitioners recommend lifestyle changes including increasing fiber intake and exercise. This study examined the effect of pea hull fiber (PHF) on loperamide-induced constipation in rats. The rats were fed either a vehicle diet or a diet enriched with PHF. The groups were divided into either a saline or loperamide injection to induce sub-acute constipation. Fecal Pellet Output (FPO) was measured for 3 days. In the saline-treated rats, PHF increased wet and dry fecal weights on day 1 and 2, and increased FPO on day 2 compared to the saline-treated rats on the vehicle diet. In the loperamide model, PHF <span>increased FPO, had higher wet and dry fecal weights on day 1 compared </span><span>to the loperamide-treated vehicle diet rats. Addition of PHF into the diet ma</span>y help improve intestinal transit in a loperamide-induced constipation rat model.
