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Hematopoietic stem and progenitor cells in HIV/AIDS and immune reconstitution 被引量:1
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作者 Jielin Zhang clyde s crumpacker 《Cell Research》 SCIE CAS CSCD 2010年第7期745-747,共3页
The human immunodeficiency virus type 1 (HIV-1) causes an acquired immunodeficiency syndrome (AIDS). HIV-1 infects human immune cells, specifically CD4+ lymphocytes, which leads to AIDS and undermines reconstitut... The human immunodeficiency virus type 1 (HIV-1) causes an acquired immunodeficiency syndrome (AIDS). HIV-1 infects human immune cells, specifically CD4+ lymphocytes, which leads to AIDS and undermines reconstitution of immunity. The unique challenges of HIV/AIDS have triggered multidisciplinary investigators to study the virology of the pathogen and the biology of the host cells, especially the interactions of HIV- 1 with T-lymphocytes, macrophages, and hematopoietic stem and progenitor cells (HSPC) [1-8]. 展开更多
关键词 人类免疫缺陷病毒 艾滋病毒 造血干细胞 细胞重建 T淋巴细胞 细胞生物学 HIV 免疫细胞
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