Helicobacter pylori (H. pylori) is one of the most common human bacterial pathogens, and infection causes a wide array of gastric disorders, including simple gastritis, peptic ulcers and gastric malignancies. Gastroin...Helicobacter pylori (H. pylori) is one of the most common human bacterial pathogens, and infection causes a wide array of gastric disorders, including simple gastritis, peptic ulcers and gastric malignancies. Gastrointestinal inflammation caused by H. pylori can influence the absorption of glucose and lipids, which are also abnormal in diabetes mellitus. Type 2 diabetes mellitus (T2DM), formerly known as non-insulin-dependent diabetes mellitus or adult-onset diabetes, is a metabolic disorder that is characterized by high levels of blood glucose resulting from insulin resistance and relative insulin deficiency. It is an emerging pandemic and is rapidly becoming a serious threat to public health. Emerging data now indicate a strong relationship between H. pylori infection and the incidence of T2DM. The mechanisms underlying the pathogenesis of diabetes are complex, involving insulin resistance, chronic inflammation, insulin secretion deficiency as a result of pancreas β-cell dysfunction, glucotoxicity, and lipotoxicity. H. pylori infection is known to be involved in the pathogenesis of insulin resistance, and the growing awareness of its role in diabetes is important for the early detection of glucose dysregulation and prevention of T2DM in high-risk communities. This review probes the possible relationship between H. pylori and diabetes according to epidemiological surveys and discusses putative mechanisms underlying this correlation.展开更多
The stability analysis of linear multistep methods for the numerical solutions of the systems of generalized neutral delay differential equations is discussed. The stability behaviour of linear multistep methods was a...The stability analysis of linear multistep methods for the numerical solutions of the systems of generalized neutral delay differential equations is discussed. The stability behaviour of linear multistep methods was analysed for the solution of the generalized system of linear neutral test equations, After the establishment of a sufficient condition for asymptotic stability of the solutions of the generalized system, it is shown that a linear multistep method is NGP(G)-stable if and only if it is A-stable.展开更多
Based on observational data and facsimile charts from Dec. 1994 to Nov. 1995 of Chinese Antarctic Great Wall Station, the local fine weather was studied. Pressure, temperature and humidity field, and aerological strat...Based on observational data and facsimile charts from Dec. 1994 to Nov. 1995 of Chinese Antarctic Great Wall Station, the local fine weather was studied. Pressure, temperature and humidity field, and aerological stratification were analyzed synoptically. Two kinds of fine weather with different physical characteristics were found; one was caused by the spreading of subtropical high with high tem- perature and high humidity, and another was connected with polar high with low temperature and low humidity. The research provide a synoptic background for the local fine weather forecast.展开更多
基金Supported by The National Natural Science Foundation of China,No.81060038 and No.81270479grants from Jiangxi Province Talent 555 Projectthe National Science and Technology Major Projects for"Major New Drugs Innovation and Development"of China,No.2011ZX09302-007-03
文摘Helicobacter pylori (H. pylori) is one of the most common human bacterial pathogens, and infection causes a wide array of gastric disorders, including simple gastritis, peptic ulcers and gastric malignancies. Gastrointestinal inflammation caused by H. pylori can influence the absorption of glucose and lipids, which are also abnormal in diabetes mellitus. Type 2 diabetes mellitus (T2DM), formerly known as non-insulin-dependent diabetes mellitus or adult-onset diabetes, is a metabolic disorder that is characterized by high levels of blood glucose resulting from insulin resistance and relative insulin deficiency. It is an emerging pandemic and is rapidly becoming a serious threat to public health. Emerging data now indicate a strong relationship between H. pylori infection and the incidence of T2DM. The mechanisms underlying the pathogenesis of diabetes are complex, involving insulin resistance, chronic inflammation, insulin secretion deficiency as a result of pancreas β-cell dysfunction, glucotoxicity, and lipotoxicity. H. pylori infection is known to be involved in the pathogenesis of insulin resistance, and the growing awareness of its role in diabetes is important for the early detection of glucose dysregulation and prevention of T2DM in high-risk communities. This review probes the possible relationship between H. pylori and diabetes according to epidemiological surveys and discusses putative mechanisms underlying this correlation.
文摘The stability analysis of linear multistep methods for the numerical solutions of the systems of generalized neutral delay differential equations is discussed. The stability behaviour of linear multistep methods was analysed for the solution of the generalized system of linear neutral test equations, After the establishment of a sufficient condition for asymptotic stability of the solutions of the generalized system, it is shown that a linear multistep method is NGP(G)-stable if and only if it is A-stable.
文摘Based on observational data and facsimile charts from Dec. 1994 to Nov. 1995 of Chinese Antarctic Great Wall Station, the local fine weather was studied. Pressure, temperature and humidity field, and aerological stratification were analyzed synoptically. Two kinds of fine weather with different physical characteristics were found; one was caused by the spreading of subtropical high with high tem- perature and high humidity, and another was connected with polar high with low temperature and low humidity. The research provide a synoptic background for the local fine weather forecast.
