Tunnel construction is susceptible to accidents such as loosening, deformation, collapse, and water inrush, especiallyunder complex geological conditions like dense fault areas. These accidents can cause instability a...Tunnel construction is susceptible to accidents such as loosening, deformation, collapse, and water inrush, especiallyunder complex geological conditions like dense fault areas. These accidents can cause instability and damageto the tunnel. As a result, it is essential to conduct research on tunnel construction and grouting reinforcementtechnology in fault fracture zones to address these issues and ensure the safety of tunnel excavation projects. Thisstudy utilized the Xianglushan cross-fault tunnel to conduct a comprehensive analysis on the construction, support,and reinforcement of a tunnel crossing a fault fracture zone using the three-dimensional finite element numericalmethod. The study yielded the following research conclusions: The excavation conditions of the cross-fault tunnelarray were analyzed to determine the optimal construction method for excavation while controlling deformationand stress in the surrounding rock. The middle partition method (CD method) was found to be the most suitable.Additionally, the effects of advanced reinforcement grouting on the cross-fault fracture zone tunnel were studied,and the optimal combination of grouting reinforcement range (140°) and grouting thickness (1m) was determined.The stress and deformation data obtained fromon-site monitoring of the surrounding rock was slightly lower thanthe numerical simulation results. However, the change trend of both sets of data was found to be consistent. Theseresearch findings provide technical analysis and data support for the construction and design of cross-fault tunnels.展开更多
Detecting primordial fluctuations from the cosmic dark ages requires extremely large low-frequency radio telescope arrays deployed on the far side of the Moon.The antenna of such an array must be lightweight,easily st...Detecting primordial fluctuations from the cosmic dark ages requires extremely large low-frequency radio telescope arrays deployed on the far side of the Moon.The antenna of such an array must be lightweight,easily storable and transportable,deployable on a large scale,durable,and capable of good electrical performance.A membrane antenna is an excellent candidate to meet these criteria.We study the design of a low-frequency membrane antenna for a lunar-based low-frequency(<30 MHz)radio telescope constructed from polyimide film widely used in aerospace applications,owing to its excellent dielectric properties and high stability as a substrate material.We first design and optimize an antenna in free space through dipole deformation and coupling principles,then simulate an antenna on the lunar surface with a simple lunar soil model,yielding an efficiency greater than 90%in the range of 12-19 MHz and greater than 10%in the range of 5-35 MHz.The antenna inherits the omni-directional radiation pattern of a simple dipole antenna in the 5-30 MHz frequency band,giving a large field of view and allowing detection of the 21 cm global signal when used alone.A demonstration prototype is constructed,and its measured electrical property is found to be consistent with simulated results using|S11|measurements.This membrane antenna can potentially fulfill the requirements of a lunar low-frequency array,establishing a solid technical foundation for future large-scale arrays for exploring the cosmic dark ages.展开更多
As one of the most stable metal-organtic framework(MOF),zeolitic imidazolate framework-8(ZIF-8)has been widely studied for applications in the field of energy storage,catalysis,and environment protection.In this paper...As one of the most stable metal-organtic framework(MOF),zeolitic imidazolate framework-8(ZIF-8)has been widely studied for applications in the field of energy storage,catalysis,and environment protection.In this paper,ZIF-8 was employed to enhance the electrochemical properties and thermal stability of the electrospun poly(vinylidene fluoride-co-hexafluoropropylene)/polyacrylonitrile(PVDF-HFP/PAN)composite separator.The results indicate that the test cells assembled with the composite separators show improved rate capability,high discharge capacity,and stable cycling performances.The addition of ZIF-8 can improve the affinity of PVDF-HFP/PAN toward liquid electrolytes,and further enhance the ionic conductivity of the composite separators.In addition,the thermal stability of the PVDF-HFP/PAN separator has been improved by ZIF-8 nanoparticles.This work can provide insight into the application of MOF materials in Li-ion batteries.展开更多
Automatic collecting of phenotypic information from plants has become a trend in breeding and smart agriculture.Targeting mature soybean plants at the harvesting stage,which are dense and overlapping,we have proposed ...Automatic collecting of phenotypic information from plants has become a trend in breeding and smart agriculture.Targeting mature soybean plants at the harvesting stage,which are dense and overlapping,we have proposed the SPP-extractor(soybean plant phenotype extractor)algorithm to acquire phenotypic traits.First,to address the mutual occultation of pods,we augmented the standard YOLOv5s model for target detection with an additional attention mechanism.The resulting model could accurately identify pods and stems and could count the entire pod set of a plant in a single scan.Second,considering that mature branches are usually bent and covered with pods,we designed a branch recognition and measurement module combining image processing,target detection,semantic segmentation,and heuristic search.Experimental results on real plants showed that SPP-extractor achieved respective R^(2) scores of 0.93–0.99 for four phenotypic traits,based on regression on manual measurements.展开更多
The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further en...The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further enhancement of the photovoltaic performance of the devices using sequential deposition.Herein,a buried interface stabilization strategy that relies on the synergy of fluorine(F)and sulfonyl(S=O)functional groups is proposed.A series of potassium salts containing halide and non-halogen anions are employed to modify SnO_(2)/perovskite buried interface.Multiple chemical bonds including hydrogen bond,coordination bond and ionic bond are realized,which strengthens interfacial contact and defect passivation effect.The chemical interaction between modification molecules and perovskite along with SnO_(2) heightens incessantly as the number of S=O and F augments.The chemical interaction strength between modifiers and perovskite as well as SnO_(2) gradually increases with the increase in the number of S=O and F.The defect passivation effect is positively correlated with the chemical interaction strength.The crystallization kinetics is regulated through the compromise between chemical interaction strength and wettability of substrates.Compared with Cl−,all non-halogen anions perform better in crystallization optimization,energy band regulation and defect passivation.The device with potassium bis(fluorosulfonyl)imide achieves a tempting efficiency of 24.17%.展开更多
Melanocortin 4 receptor(MC4R),the most important monogenetic cause of human metabolic disorders,has been of great interest to many researchers in the field of energy homeostasis and public health.Because MC4R is a vit...Melanocortin 4 receptor(MC4R),the most important monogenetic cause of human metabolic disorders,has been of great interest to many researchers in the field of energy homeostasis and public health.Because MC4R is a vital pharmaceutical target for maintaining controllable appetite and body weight for professional athletes,previous studies have mainly focused on the central,rather than the peripheral,roles of MC4R.Thus,the local expression of MC4R and its behavioral regulation remain unclear.In an attempt to shed light on different directions for future studies of MC4R signaling,we review a series of recent and important studies exploring the peripheral functions of MC4R and the direct physiological interaction between peripheral organs and central MC4R neurons in this article.展开更多
SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a v...SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a variety of ways,but it is still difficult to achieve a precisely located fault attacks at a low cost,whereas a Hardware Trojan(HT)can realize this.Temperature,as a physical quantity incidental to the operation of a cryptographic device,is easily overlooked.In this paper,a temperature-triggered HT(THT)is designed,which,when activated,causes a specific bit of the intermediate state of the SKINNY-64-64 to be flipped.Further,in this paper,a THT-based algebraic fault analysis(THT-AFA)method is proposed.To demonstrate the effectiveness of the method,experiments on algebraic fault analysis(AFA)and THT-AFA have been carried out on SKINNY-64-64.In the THT-AFA for SKINNY-64-64,it is only required to activate the THT 3 times to obtain the master key with a 100%success rate,and the average time for the attack is 64.57 s.However,when performing AFA on this cipher,we provide a relation-ship between the number of different faults and the residual entropy of the key.In comparison,our proposed THT-AFA method has better performance in terms of attack efficiency.To the best of our knowledge,this is the first HT attack on SKINNY-64-64.展开更多
When the Transformer proposed by Google in 2017,it was first used for machine translation tasks and achieved the state of the art at that time.Although the current neural machine translation model can generate high qu...When the Transformer proposed by Google in 2017,it was first used for machine translation tasks and achieved the state of the art at that time.Although the current neural machine translation model can generate high quality translation results,there are still mistranslations and omissions in the translation of key information of long sentences.On the other hand,the most important part in traditional translation tasks is the translation of key information.In the translation results,as long as the key information is translated accurately and completely,even if other parts of the results are translated incorrect,the final translation results’quality can still be guaranteed.In order to solve the problem of mistranslation and missed translation effectively,and improve the accuracy and completeness of long sentence translation in machine translation,this paper proposes a key information fused neural machine translation model based on Transformer.The model proposed in this paper extracts the keywords of the source language text separately as the input of the encoder.After the same encoding as the source language text,it is fused with the output of the source language text encoded by the encoder,then the key information is processed and input into the decoder.With incorporating keyword information from the source language sentence,the model’s performance in the task of translating long sentences is very reliable.In order to verify the effectiveness of the method of fusion of key information proposed in this paper,a series of experiments were carried out on the verification set.The experimental results show that the Bilingual Evaluation Understudy(BLEU)score of the model proposed in this paper on theWorkshop on Machine Translation(WMT)2017 test dataset is higher than the BLEU score of Transformer proposed by Google on the WMT2017 test dataset.The experimental results show the advantages of the model proposed in this paper.展开更多
BACKGROUND Postoperative complications of triceps surae intramuscular hemangioma surgery with talipes equinovarus have rarely been described,and the evidence for treatment is limited.The purpose of this case study was...BACKGROUND Postoperative complications of triceps surae intramuscular hemangioma surgery with talipes equinovarus have rarely been described,and the evidence for treatment is limited.The purpose of this case study was to report the new application of the Ilizarov technique,which successfully treated talipes equinovarus in adults after triceps surae intramuscular hemangioma.CASE SUMMARY A 29-year-old woman treated with the Ilizarov technique for talipes equinovarus in the right leg after triceps surae intramuscular hemangioma surgery.The equinus deformity was roughly corrected after 2 years of follow-up,without significant secondary sequelae.CONCLUSION Talipes equinovarus caused by postoperative sequelae of intramuscular hemangioma was successfully corrected by the Ilizarov technique.The Ilizarov technique may be used for treating talipes equinovarus caused by various causes.展开更多
The current adversarial attacks against deep learning models have achieved incredible success in the white-box scenario.However,they often exhibit weak transferability in the black-box scenario,especially when attacki...The current adversarial attacks against deep learning models have achieved incredible success in the white-box scenario.However,they often exhibit weak transferability in the black-box scenario,especially when attacking those with defense mechanisms.In this work,we propose a new transfer-based blackbox attack called the channel decomposition attack method(CDAM).It can attack multiple black-box models by enhancing the transferability of the adversarial examples.On the one hand,it tunes the gradient and stabilizes the update direction by decomposing the channels of the input example and calculating the aggregate gradient.On the other hand,it helps to escape from local optima by initializing the data point with random noise.Besides,it could combine with other transfer-based attacks flexibly.Extensive experiments on the standard ImageNet dataset show that our method could significantly improve the transferability of adversarial attacks.Compared with the state-of-the-art method,our approach improves the average success rate from 88.2%to 96.6%when attacking three adversarially trained black-box models,demonstrating the remaining shortcomings of existing deep learning models.展开更多
BACKGROUND Rotationplasty is often performed for malignant tumors,but type BIIIb rotationplasty is rarely reported,and there needs to be more evidence of the procedure and treatment.The purpose of this case study was ...BACKGROUND Rotationplasty is often performed for malignant tumors,but type BIIIb rotationplasty is rarely reported,and there needs to be more evidence of the procedure and treatment.The purpose of this case study was to report a new direction in the use of type BIIIb rotationplasty in treating patients with limb salvage and longterm non-healing infections.CASE SUMMARY Case 1:A 47-year-old man underwent radiotherapy for hemangioendothelioma in his left thigh,resulting in a femoral fracture.Despite the use of plates,intramedullary nailing,and external fixators,the femoral bone failed to unite due to infectious nonunion.Multiple operations were unable to control the infection,leaving the patient immobile.We performed a modified tibia-pelvic-constrained hip rotationplasty,utilizing a constrained prosthetic hip between the tibia and pelvis following a femur resection.Two years post-surgery,the patient was able to walk with the prosthetic device without any signs of recurring infection.The corresponding functional scores were 72 points for the Musculoskeletal Tumor Society(MSTS),53 for the Functional Mobility Assessment(FMA),93 for the Toronto Extremity Salvage Score(TESS),and 56 for the MOS 36-item short form health survey(SF-36).Case 2:A 59-year-old woman presented with liposarcoma in her left thigh.Magnetic resonance imaging revealed tumors in the medial,anterior,and posterior femur muscles,encircling the femoral vessels and nerves.Fortunately,there were no symptoms of sciatic dysfunction,and the tumor had not invaded the sciatic nucleus.After one year of follow-up,the patient expressed satisfaction with limb preservation post-type BIIIb rotationplasty.The corresponding functional scores were 63 points for the MSTS,47 for the FMA,88 for the TESS,and 52 for the SF-36.CONCLUSION Our study suggests that type BIIIb rotationplasty may be an alternative to amputation in patients with incurable infections.For malignant tumors of the lower extremities without invasion of the sciatic nerve,type BIIIb rotationplasty remains an excellent alternative to amputation.This surgical method may prevent amputation,improve functional outcomes,and facilitate biological reconstruction.展开更多
<strong>Background:</strong> As a common surgical disease, pressure injury has become a long-standing problem in clinical treatment and nursing process. This research was conducted to explore the feasibili...<strong>Background:</strong> As a common surgical disease, pressure injury has become a long-standing problem in clinical treatment and nursing process. This research was conducted to explore the feasibility of Ji Desheng Snake Pills combined with hypertonic glucose external application in the treatment of stage III and IV pressure injuries. <strong>Methods:</strong> Patients with stage III and IV pressure injuries, who received treatment in our hospital between December 2018 and December 2019 were selected and divided into experimental group, conventional treatment group, and control group, 30 cases for each. The three groups received Ji Desheng Snake Pills combined with hypertonic glucose external application, moist dressing external application and surgical dressing change, respectively. The safety, therapeutic effect and cost benefit of the three treatment methods were compared. <strong>Results:</strong> There were no adverse reactions in the three groups of patients. The PUSH scores of the experimental group and the conventional treatment group were significantly lower than that of the control group on the 14<sup>th</sup>, 21<sup>th</sup>, and 28<sup>th</sup> days, and the result was statistically significant (p < 0.05), while there was no significant difference between the experimental group and the conventional treatment group (p > 0.05). The wound healing rates of the experimental group (70.14 ± 8.27%) and the conventional treatment group (73.99 ± 7.15%) were significantly higher than that of the control group (43.25 ± 8.53%) on the 28<sup>th</sup> day, with statistical significance (p < 0.05);there was no significant difference between the experimental group and the conventional treatment group (p > 0.05). The total treatment costs of the three groups were 569.73 ± 78.12 yuan, 1043.40 ± 135.31 yuan, and 186.47 ± 30.29 yuan. The cost of the conventional treatment group was the highest, followed by the experimental group, and the control group was the lowest. The result was statistically significant (p < 0.05). <strong>Conclusion:</strong> In the treatment of stage III and IV pressure injuries, there was no significant difference in the safety and therapeutic effect between the experimental group (Ji Desheng Snake Pills combined with hypertonic glucose external application) and the conventional treatment group (moist dressing external application), but the experimental group had better cost benefit.展开更多
Rosmarinic acid（RA） can elicit a neuroprotective effect against ischemic stroke, but the precise molecular mechanism remains poorly understood. In this study, an experimental ischemic stroke model was established in...Rosmarinic acid（RA） can elicit a neuroprotective effect against ischemic stroke, but the precise molecular mechanism remains poorly understood. In this study, an experimental ischemic stroke model was established in CD-1 mice（Beijing Vital River Laboratory Animal Technology, Beijing, China） by occluding the right middle cerebral artery for 1 hour and allowing reperfusion for 24 hours. After intraperitoneally injecting model mice with 10, 20, or 40 mg/kg RA, functional neurological deficits were evaluated using modified Longa scores. Subsequently, cerebral infarct volume was measured using TTC staining and ischemic brain tissue was examined for cell apoptosis with TUNEL staining. Superoxide dismutase activity and malondialdehyde levels were measured by spectrophometry. Expression of heme oxygenase-1（HO-1）, nuclear factor erythroid 2-related factor 2（Nrf2）, Bcl-2, Bax, Akt, and phospho-Ser473 Akt proteins in ischemic brain tissue was detected by western blot, while mRNA levels of Nrf2, HO-1, Bcl-2, and Bax were analyzed using real time quantitative PCR. In addition, HO-1 enzyme activity was measured spectrophotometrically. RA（20 and 40 mg/kg） greatly improved neurological function, reduced infarct volume, decreased cell apoptosis, upregulated Bcl-2 protein and mRNA expression, downregulated Bax protein and mRNA expression, increased HO-1 and Nrf2 protein and mRNA expression, increased superoxide dismutase activity, and decreased malondialdehyde levels in ischemic brain tissue of model mice. However, intraperitoneal injection of a HO-1 inhibitor（10 mg/kg zinc protoporphyrin IX） reversed the neuroprotective effects of RA on HO-1 enzyme activity and Bcl-2 and Bax protein expression. The PI3 K/Akt signaling pathway inhibitor LY294002（10 mM） inhibited Akt phosphorylation, as well as Nrf2 and HO-1 expression. Our findings suggest that RA has anti-oxidative and anti-apoptotic properties that protect against ischemic stroke by a mechanism involving upregulation of Nrf2 and HO-1 expression via the PI3 K/Akt signaling pathway.展开更多
The machine-learning approach was investigated to predict the mechanical properties of Cu–Al alloys manufactured using the powder metallurgy technique to increase the rate of fabrication and characterization of new m...The machine-learning approach was investigated to predict the mechanical properties of Cu–Al alloys manufactured using the powder metallurgy technique to increase the rate of fabrication and characterization of new materials and provide physical insights into their properties.Six algorithms were used to construct the prediction models, with chemical composition and porosity of the compacts chosen as the descriptors.The results show that the sequential minimal optimization algorithm for support vector regression with a puk kernel(SMOreg/puk) model demonstrated the best prediction ability. Specifically, its predictions exhibited the highest correlation coefficient and lowest error among the predictions of the six models. The SMOreg/puk model was subsequently applied to predict the tensile strength and hardness of Cu–Al alloys and provide guidance for composition design to achieve the expected values. With the guidance of the SMOreg/puk model, Cu–12Al–6Ni alloy with a tensile strength(390 MPa) and hardness(HB 139) that reached the expected values was developed.展开更多
By adopting the differential age method, we select 17 832 luminous red galaxies from the Sloan Digital Sky Survey Data Release Seven covering redshift 0 〈 z 〈 0.4 to measure the Hubble parameter. Using the full spec...By adopting the differential age method, we select 17 832 luminous red galaxies from the Sloan Digital Sky Survey Data Release Seven covering redshift 0 〈 z 〈 0.4 to measure the Hubble parameter. Using the full spectrum fitting package UZySS, these spectra are reduced with single stellar population models and optimal age information from our selected sample is derived. With the decreasing age-redshift relation, four new observational H（z） data （OHD） points are obtained, which are H（z） = 69.0 ± 19.6 km s^-1 Mpc^-1 at z = 0.07, H（z） = 68.6± 26.2 km s^-1 Mpc^-1 at z = 0.12, H（z）=72.9 ± 29.6 km s^-1 Mpc^-1 at z = 0.2 and H（z）=88.8 ± 36.6 km s^-1 Mpc^-1 at z = 0.28, respectively. Combined with 21 other available OHD data points, the performance of the constraint on both flat and non-flat ACDM models is presented.展开更多
While the high-energy radiation effects on polypropylene, which are crucial for the cable industry for nuclear power plants, have been thoroughly studied, the property changes of PP at low-dose-rate electron-beam irra...While the high-energy radiation effects on polypropylene, which are crucial for the cable industry for nuclear power plants, have been thoroughly studied, the property changes of PP at low-dose-rate electron-beam irradiation are far from elucidated. Herein, the influence of electron-beam irradiation on the structure and properties of PP was examined. The static EB irradiation conditions were 1.2 MeV at a low dose rate of 20 kGy/h to achieve absorbed doses ranging from 45, to 60, 100, and 200 kGy.The molecular structure was first evaluated by measuring the carboxyl index and the relative radical concentrations via Fourier transform infrared spectroscopy and electron spin resonance, respectively. Mechanical, differential scanning colorimetric, and rheological tests were carried out to further investigate the changes in the properties(tensile, crystalizing, and viscoelastic properties) of irradiated PP, which showed good agreement with the structural analysis results. We found that radio-oxidative degradation(chain scission) was predominant, which can be due to the low dose rate facilitating oxygen diffusion into the PP matrix during electron-beam irradiation.展开更多
基金the Postgraduate Research and Practice Innovation Program of Jiangsu Province(Grant No.KYCX22_0621)the National Natural Science Foundation of China(Grant No.52209130)Jiangsu Funding Program for Excellent Postdoctoral Talent.
文摘Tunnel construction is susceptible to accidents such as loosening, deformation, collapse, and water inrush, especiallyunder complex geological conditions like dense fault areas. These accidents can cause instability and damageto the tunnel. As a result, it is essential to conduct research on tunnel construction and grouting reinforcementtechnology in fault fracture zones to address these issues and ensure the safety of tunnel excavation projects. Thisstudy utilized the Xianglushan cross-fault tunnel to conduct a comprehensive analysis on the construction, support,and reinforcement of a tunnel crossing a fault fracture zone using the three-dimensional finite element numericalmethod. The study yielded the following research conclusions: The excavation conditions of the cross-fault tunnelarray were analyzed to determine the optimal construction method for excavation while controlling deformationand stress in the surrounding rock. The middle partition method (CD method) was found to be the most suitable.Additionally, the effects of advanced reinforcement grouting on the cross-fault fracture zone tunnel were studied,and the optimal combination of grouting reinforcement range (140°) and grouting thickness (1m) was determined.The stress and deformation data obtained fromon-site monitoring of the surrounding rock was slightly lower thanthe numerical simulation results. However, the change trend of both sets of data was found to be consistent. Theseresearch findings provide technical analysis and data support for the construction and design of cross-fault tunnels.
基金We acknowledge the support of the National SKA program of China(2022SKA0110100,2022SKA0110101)the Natural Science Foundation of China(12273070,12203061,1236114814,12303004).
文摘Detecting primordial fluctuations from the cosmic dark ages requires extremely large low-frequency radio telescope arrays deployed on the far side of the Moon.The antenna of such an array must be lightweight,easily storable and transportable,deployable on a large scale,durable,and capable of good electrical performance.A membrane antenna is an excellent candidate to meet these criteria.We study the design of a low-frequency membrane antenna for a lunar-based low-frequency(<30 MHz)radio telescope constructed from polyimide film widely used in aerospace applications,owing to its excellent dielectric properties and high stability as a substrate material.We first design and optimize an antenna in free space through dipole deformation and coupling principles,then simulate an antenna on the lunar surface with a simple lunar soil model,yielding an efficiency greater than 90%in the range of 12-19 MHz and greater than 10%in the range of 5-35 MHz.The antenna inherits the omni-directional radiation pattern of a simple dipole antenna in the 5-30 MHz frequency band,giving a large field of view and allowing detection of the 21 cm global signal when used alone.A demonstration prototype is constructed,and its measured electrical property is found to be consistent with simulated results using|S11|measurements.This membrane antenna can potentially fulfill the requirements of a lunar low-frequency array,establishing a solid technical foundation for future large-scale arrays for exploring the cosmic dark ages.
基金supported by National Natural Science Foundation of China(12002295)Key Scientific Research Project of Education Department of Hunan Province,Xiangtan City,China(22A0113)Major Science and Technology Projects of Xiangtan Science and Technology Bureau(GX-ZD202210011).
文摘As one of the most stable metal-organtic framework(MOF),zeolitic imidazolate framework-8(ZIF-8)has been widely studied for applications in the field of energy storage,catalysis,and environment protection.In this paper,ZIF-8 was employed to enhance the electrochemical properties and thermal stability of the electrospun poly(vinylidene fluoride-co-hexafluoropropylene)/polyacrylonitrile(PVDF-HFP/PAN)composite separator.The results indicate that the test cells assembled with the composite separators show improved rate capability,high discharge capacity,and stable cycling performances.The addition of ZIF-8 can improve the affinity of PVDF-HFP/PAN toward liquid electrolytes,and further enhance the ionic conductivity of the composite separators.In addition,the thermal stability of the PVDF-HFP/PAN separator has been improved by ZIF-8 nanoparticles.This work can provide insight into the application of MOF materials in Li-ion batteries.
基金supported by the National Natural Science Foundation of China(62276032,32072016)the Agricultural Science and Technology Innovation Program(ASTIP)of Chinese Academy of Agricultural Sciences。
文摘Automatic collecting of phenotypic information from plants has become a trend in breeding and smart agriculture.Targeting mature soybean plants at the harvesting stage,which are dense and overlapping,we have proposed the SPP-extractor(soybean plant phenotype extractor)algorithm to acquire phenotypic traits.First,to address the mutual occultation of pods,we augmented the standard YOLOv5s model for target detection with an additional attention mechanism.The resulting model could accurately identify pods and stems and could count the entire pod set of a plant in a single scan.Second,considering that mature branches are usually bent and covered with pods,we designed a branch recognition and measurement module combining image processing,target detection,semantic segmentation,and heuristic search.Experimental results on real plants showed that SPP-extractor achieved respective R^(2) scores of 0.93–0.99 for four phenotypic traits,based on regression on manual measurements.
基金supported by the Defense Industrial Technology Development Program(JCKY2017110C0654)National Natural Science Foundation of China(11974063,61904023,62274018)+1 种基金Chongqing Special Postdoctoral Science Foundation(cstc2019jcyj-bsh0026)Fundamental Research Funds for the Central Universities(2021CDJQY-022).
文摘The interfacial defects and energy barrier are main reasons for interfacial nonradiative recombination.In addition,poor perovskite crystallization and incomplete conversion of PbI_(2) to perovskite restrict further enhancement of the photovoltaic performance of the devices using sequential deposition.Herein,a buried interface stabilization strategy that relies on the synergy of fluorine(F)and sulfonyl(S=O)functional groups is proposed.A series of potassium salts containing halide and non-halogen anions are employed to modify SnO_(2)/perovskite buried interface.Multiple chemical bonds including hydrogen bond,coordination bond and ionic bond are realized,which strengthens interfacial contact and defect passivation effect.The chemical interaction between modification molecules and perovskite along with SnO_(2) heightens incessantly as the number of S=O and F augments.The chemical interaction strength between modifiers and perovskite as well as SnO_(2) gradually increases with the increase in the number of S=O and F.The defect passivation effect is positively correlated with the chemical interaction strength.The crystallization kinetics is regulated through the compromise between chemical interaction strength and wettability of substrates.Compared with Cl−,all non-halogen anions perform better in crystallization optimization,energy band regulation and defect passivation.The device with potassium bis(fluorosulfonyl)imide achieves a tempting efficiency of 24.17%.
基金Fundings supported by grants from the National Key Research and Development Program of China(Grant No.2017YFA0103902,2018YFA0800300,2019YFA0801900,2019YFA0111400)National Natural Science Foundation of China(Grant No.31771283,91749104,31971074)+3 种基金the Fundamental Research Funds for the Central Universities of Tongji University(No.22120190210)Innovative Research Team of High-Level Local Universities in Shanghai(No.SSMUZDCX20180700)Key Laboratory Program of the Education Commission of Shanghai Municipality(No.DSYS14005)the Science and Technology Innovation Action Plan of Shanghai Science and Technology Committee(No.18140901300).
文摘Melanocortin 4 receptor(MC4R),the most important monogenetic cause of human metabolic disorders,has been of great interest to many researchers in the field of energy homeostasis and public health.Because MC4R is a vital pharmaceutical target for maintaining controllable appetite and body weight for professional athletes,previous studies have mainly focused on the central,rather than the peripheral,roles of MC4R.Thus,the local expression of MC4R and its behavioral regulation remain unclear.In an attempt to shed light on different directions for future studies of MC4R signaling,we review a series of recent and important studies exploring the peripheral functions of MC4R and the direct physiological interaction between peripheral organs and central MC4R neurons in this article.
基金supported in part by the Natural Science Foundation of Heilongjiang Province of China(Grant No.LH2022F053)in part by the Scientific and technological development project of the central government guiding local(Grant No.SBZY2021E076)+2 种基金in part by the PostdoctoralResearch Fund Project of Heilongjiang Province of China(Grant No.LBH-Q21195)in part by the Fundamental Research Funds of Heilongjiang Provincial Universities of China(Grant No.145209146)in part by the National Natural Science Foundation of China(NSFC)(Grant No.61501275).
文摘SKINNY-64-64 is a lightweight block cipher with a 64-bit block length and key length,and it is mainly used on the Internet of Things(IoT).Currently,faults can be injected into cryptographic devices by attackers in a variety of ways,but it is still difficult to achieve a precisely located fault attacks at a low cost,whereas a Hardware Trojan(HT)can realize this.Temperature,as a physical quantity incidental to the operation of a cryptographic device,is easily overlooked.In this paper,a temperature-triggered HT(THT)is designed,which,when activated,causes a specific bit of the intermediate state of the SKINNY-64-64 to be flipped.Further,in this paper,a THT-based algebraic fault analysis(THT-AFA)method is proposed.To demonstrate the effectiveness of the method,experiments on algebraic fault analysis(AFA)and THT-AFA have been carried out on SKINNY-64-64.In the THT-AFA for SKINNY-64-64,it is only required to activate the THT 3 times to obtain the master key with a 100%success rate,and the average time for the attack is 64.57 s.However,when performing AFA on this cipher,we provide a relation-ship between the number of different faults and the residual entropy of the key.In comparison,our proposed THT-AFA method has better performance in terms of attack efficiency.To the best of our knowledge,this is the first HT attack on SKINNY-64-64.
基金Major Science and Technology Project of Sichuan Province[No.2022YFG0315,2022YFG0174]Sichuan Gas Turbine Research Institute stability support project of China Aero Engine Group Co.,Ltd.[No.GJCZ-2019-71].
文摘When the Transformer proposed by Google in 2017,it was first used for machine translation tasks and achieved the state of the art at that time.Although the current neural machine translation model can generate high quality translation results,there are still mistranslations and omissions in the translation of key information of long sentences.On the other hand,the most important part in traditional translation tasks is the translation of key information.In the translation results,as long as the key information is translated accurately and completely,even if other parts of the results are translated incorrect,the final translation results’quality can still be guaranteed.In order to solve the problem of mistranslation and missed translation effectively,and improve the accuracy and completeness of long sentence translation in machine translation,this paper proposes a key information fused neural machine translation model based on Transformer.The model proposed in this paper extracts the keywords of the source language text separately as the input of the encoder.After the same encoding as the source language text,it is fused with the output of the source language text encoded by the encoder,then the key information is processed and input into the decoder.With incorporating keyword information from the source language sentence,the model’s performance in the task of translating long sentences is very reliable.In order to verify the effectiveness of the method of fusion of key information proposed in this paper,a series of experiments were carried out on the verification set.The experimental results show that the Bilingual Evaluation Understudy(BLEU)score of the model proposed in this paper on theWorkshop on Machine Translation(WMT)2017 test dataset is higher than the BLEU score of Transformer proposed by Google on the WMT2017 test dataset.The experimental results show the advantages of the model proposed in this paper.
基金Supported by Zhangzhou Natural Science Foundation Projects in 2019,No.ZZ2019J19。
文摘BACKGROUND Postoperative complications of triceps surae intramuscular hemangioma surgery with talipes equinovarus have rarely been described,and the evidence for treatment is limited.The purpose of this case study was to report the new application of the Ilizarov technique,which successfully treated talipes equinovarus in adults after triceps surae intramuscular hemangioma.CASE SUMMARY A 29-year-old woman treated with the Ilizarov technique for talipes equinovarus in the right leg after triceps surae intramuscular hemangioma surgery.The equinus deformity was roughly corrected after 2 years of follow-up,without significant secondary sequelae.CONCLUSION Talipes equinovarus caused by postoperative sequelae of intramuscular hemangioma was successfully corrected by the Ilizarov technique.The Ilizarov technique may be used for treating talipes equinovarus caused by various causes.
基金This work was supported by Sichuan Science and Technology Program[No.2022YFG0315,2022YFG0174]Sichuan Gas Turbine Research Institute stability support project of China Aero Engine Group Co.,Ltd.[GJCZ-2019-71]Key project of Chengdu[No.2019-YF09-00044-CG].
文摘The current adversarial attacks against deep learning models have achieved incredible success in the white-box scenario.However,they often exhibit weak transferability in the black-box scenario,especially when attacking those with defense mechanisms.In this work,we propose a new transfer-based blackbox attack called the channel decomposition attack method(CDAM).It can attack multiple black-box models by enhancing the transferability of the adversarial examples.On the one hand,it tunes the gradient and stabilizes the update direction by decomposing the channels of the input example and calculating the aggregate gradient.On the other hand,it helps to escape from local optima by initializing the data point with random noise.Besides,it could combine with other transfer-based attacks flexibly.Extensive experiments on the standard ImageNet dataset show that our method could significantly improve the transferability of adversarial attacks.Compared with the state-of-the-art method,our approach improves the average success rate from 88.2%to 96.6%when attacking three adversarially trained black-box models,demonstrating the remaining shortcomings of existing deep learning models.
基金Supported by the Army Logistics Scientific Research Projects,No.CNJ16C013.
文摘BACKGROUND Rotationplasty is often performed for malignant tumors,but type BIIIb rotationplasty is rarely reported,and there needs to be more evidence of the procedure and treatment.The purpose of this case study was to report a new direction in the use of type BIIIb rotationplasty in treating patients with limb salvage and longterm non-healing infections.CASE SUMMARY Case 1:A 47-year-old man underwent radiotherapy for hemangioendothelioma in his left thigh,resulting in a femoral fracture.Despite the use of plates,intramedullary nailing,and external fixators,the femoral bone failed to unite due to infectious nonunion.Multiple operations were unable to control the infection,leaving the patient immobile.We performed a modified tibia-pelvic-constrained hip rotationplasty,utilizing a constrained prosthetic hip between the tibia and pelvis following a femur resection.Two years post-surgery,the patient was able to walk with the prosthetic device without any signs of recurring infection.The corresponding functional scores were 72 points for the Musculoskeletal Tumor Society(MSTS),53 for the Functional Mobility Assessment(FMA),93 for the Toronto Extremity Salvage Score(TESS),and 56 for the MOS 36-item short form health survey(SF-36).Case 2:A 59-year-old woman presented with liposarcoma in her left thigh.Magnetic resonance imaging revealed tumors in the medial,anterior,and posterior femur muscles,encircling the femoral vessels and nerves.Fortunately,there were no symptoms of sciatic dysfunction,and the tumor had not invaded the sciatic nucleus.After one year of follow-up,the patient expressed satisfaction with limb preservation post-type BIIIb rotationplasty.The corresponding functional scores were 63 points for the MSTS,47 for the FMA,88 for the TESS,and 52 for the SF-36.CONCLUSION Our study suggests that type BIIIb rotationplasty may be an alternative to amputation in patients with incurable infections.For malignant tumors of the lower extremities without invasion of the sciatic nerve,type BIIIb rotationplasty remains an excellent alternative to amputation.This surgical method may prevent amputation,improve functional outcomes,and facilitate biological reconstruction.
文摘<strong>Background:</strong> As a common surgical disease, pressure injury has become a long-standing problem in clinical treatment and nursing process. This research was conducted to explore the feasibility of Ji Desheng Snake Pills combined with hypertonic glucose external application in the treatment of stage III and IV pressure injuries. <strong>Methods:</strong> Patients with stage III and IV pressure injuries, who received treatment in our hospital between December 2018 and December 2019 were selected and divided into experimental group, conventional treatment group, and control group, 30 cases for each. The three groups received Ji Desheng Snake Pills combined with hypertonic glucose external application, moist dressing external application and surgical dressing change, respectively. The safety, therapeutic effect and cost benefit of the three treatment methods were compared. <strong>Results:</strong> There were no adverse reactions in the three groups of patients. The PUSH scores of the experimental group and the conventional treatment group were significantly lower than that of the control group on the 14<sup>th</sup>, 21<sup>th</sup>, and 28<sup>th</sup> days, and the result was statistically significant (p < 0.05), while there was no significant difference between the experimental group and the conventional treatment group (p > 0.05). The wound healing rates of the experimental group (70.14 ± 8.27%) and the conventional treatment group (73.99 ± 7.15%) were significantly higher than that of the control group (43.25 ± 8.53%) on the 28<sup>th</sup> day, with statistical significance (p < 0.05);there was no significant difference between the experimental group and the conventional treatment group (p > 0.05). The total treatment costs of the three groups were 569.73 ± 78.12 yuan, 1043.40 ± 135.31 yuan, and 186.47 ± 30.29 yuan. The cost of the conventional treatment group was the highest, followed by the experimental group, and the control group was the lowest. The result was statistically significant (p < 0.05). <strong>Conclusion:</strong> In the treatment of stage III and IV pressure injuries, there was no significant difference in the safety and therapeutic effect between the experimental group (Ji Desheng Snake Pills combined with hypertonic glucose external application) and the conventional treatment group (moist dressing external application), but the experimental group had better cost benefit.
基金supported by the National Natural Science Foundation of China,No.81571292(to XJZ)、81601152(to YY)the Natural Science Foundation of Hebei Province of China,No.H2017206338(to RC)
文摘Rosmarinic acid（RA） can elicit a neuroprotective effect against ischemic stroke, but the precise molecular mechanism remains poorly understood. In this study, an experimental ischemic stroke model was established in CD-1 mice（Beijing Vital River Laboratory Animal Technology, Beijing, China） by occluding the right middle cerebral artery for 1 hour and allowing reperfusion for 24 hours. After intraperitoneally injecting model mice with 10, 20, or 40 mg/kg RA, functional neurological deficits were evaluated using modified Longa scores. Subsequently, cerebral infarct volume was measured using TTC staining and ischemic brain tissue was examined for cell apoptosis with TUNEL staining. Superoxide dismutase activity and malondialdehyde levels were measured by spectrophometry. Expression of heme oxygenase-1（HO-1）, nuclear factor erythroid 2-related factor 2（Nrf2）, Bcl-2, Bax, Akt, and phospho-Ser473 Akt proteins in ischemic brain tissue was detected by western blot, while mRNA levels of Nrf2, HO-1, Bcl-2, and Bax were analyzed using real time quantitative PCR. In addition, HO-1 enzyme activity was measured spectrophotometrically. RA（20 and 40 mg/kg） greatly improved neurological function, reduced infarct volume, decreased cell apoptosis, upregulated Bcl-2 protein and mRNA expression, downregulated Bax protein and mRNA expression, increased HO-1 and Nrf2 protein and mRNA expression, increased superoxide dismutase activity, and decreased malondialdehyde levels in ischemic brain tissue of model mice. However, intraperitoneal injection of a HO-1 inhibitor（10 mg/kg zinc protoporphyrin IX） reversed the neuroprotective effects of RA on HO-1 enzyme activity and Bcl-2 and Bax protein expression. The PI3 K/Akt signaling pathway inhibitor LY294002（10 mM） inhibited Akt phosphorylation, as well as Nrf2 and HO-1 expression. Our findings suggest that RA has anti-oxidative and anti-apoptotic properties that protect against ischemic stroke by a mechanism involving upregulation of Nrf2 and HO-1 expression via the PI3 K/Akt signaling pathway.
基金financial support from the National Key Research and Development Program of China(No.2016YFB0700503)the National High Technology Research and Development Program of China(No.2015AA03420)+2 种基金Beijing Science and Technology Plan(No.D16110300240000)National Natural Science Foundation of China(No.51172018)the Science and Technology Research Program of Chongqing Municipal Education Commission(No.KJQN201801202)
文摘The machine-learning approach was investigated to predict the mechanical properties of Cu–Al alloys manufactured using the powder metallurgy technique to increase the rate of fabrication and characterization of new materials and provide physical insights into their properties.Six algorithms were used to construct the prediction models, with chemical composition and porosity of the compacts chosen as the descriptors.The results show that the sequential minimal optimization algorithm for support vector regression with a puk kernel(SMOreg/puk) model demonstrated the best prediction ability. Specifically, its predictions exhibited the highest correlation coefficient and lowest error among the predictions of the six models. The SMOreg/puk model was subsequently applied to predict the tensile strength and hardness of Cu–Al alloys and provide guidance for composition design to achieve the expected values. With the guidance of the SMOreg/puk model, Cu–12Al–6Ni alloy with a tensile strength(390 MPa) and hardness(HB 139) that reached the expected values was developed.
基金supported by the National Natural Science Foundation of China
文摘By adopting the differential age method, we select 17 832 luminous red galaxies from the Sloan Digital Sky Survey Data Release Seven covering redshift 0 〈 z 〈 0.4 to measure the Hubble parameter. Using the full spectrum fitting package UZySS, these spectra are reduced with single stellar population models and optimal age information from our selected sample is derived. With the decreasing age-redshift relation, four new observational H（z） data （OHD） points are obtained, which are H（z） = 69.0 ± 19.6 km s^-1 Mpc^-1 at z = 0.07, H（z） = 68.6± 26.2 km s^-1 Mpc^-1 at z = 0.12, H（z）=72.9 ± 29.6 km s^-1 Mpc^-1 at z = 0.2 and H（z）=88.8 ± 36.6 km s^-1 Mpc^-1 at z = 0.28, respectively. Combined with 21 other available OHD data points, the performance of the constraint on both flat and non-flat ACDM models is presented.
基金supported by the "Strategic Priority Research Program" of the Chinese Academy of Science(No.XDA02040300)the National Natural Science Foundation of China(No.11575277)
文摘While the high-energy radiation effects on polypropylene, which are crucial for the cable industry for nuclear power plants, have been thoroughly studied, the property changes of PP at low-dose-rate electron-beam irradiation are far from elucidated. Herein, the influence of electron-beam irradiation on the structure and properties of PP was examined. The static EB irradiation conditions were 1.2 MeV at a low dose rate of 20 kGy/h to achieve absorbed doses ranging from 45, to 60, 100, and 200 kGy.The molecular structure was first evaluated by measuring the carboxyl index and the relative radical concentrations via Fourier transform infrared spectroscopy and electron spin resonance, respectively. Mechanical, differential scanning colorimetric, and rheological tests were carried out to further investigate the changes in the properties(tensile, crystalizing, and viscoelastic properties) of irradiated PP, which showed good agreement with the structural analysis results. We found that radio-oxidative degradation(chain scission) was predominant, which can be due to the low dose rate facilitating oxygen diffusion into the PP matrix during electron-beam irradiation.
