Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other,and thus affect host health and immune-mediated diseases.Here,we systematically review the current understa...Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other,and thus affect host health and immune-mediated diseases.Here,we systematically review the current understanding linking dietary nutrients to gut microbiota-host immune interactions,emphasizing how this axis might influence host immunity in health and diseases.Of relevance,we highlight that the implications of gut microbiota-targeted dietary intervention could be harnessed in orchestrating a spectrum of immune-associated diseases.展开更多
基金supported by the National Key Research and Development Program of China(2021YFD1300700,2021YFD1300201,2022YFA1304201)the National Natural Science Foundation of China(32225047,U22A20510,32125036,32172750,31972596,31902170,31630074,32272916,32102567)+4 种基金the Laboratory of Lingnan Modern Agriculture Project(NT2021005)the China Agricultural Research System of MOF and MARA(CARS-35)the Key Research and Development Project of Hainan Province(ZDYF2021XDNY177)the 111 Project(B16044)the Program for Shaanxi Science and Technology(2022KJXX-13).
文摘Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other,and thus affect host health and immune-mediated diseases.Here,we systematically review the current understanding linking dietary nutrients to gut microbiota-host immune interactions,emphasizing how this axis might influence host immunity in health and diseases.Of relevance,we highlight that the implications of gut microbiota-targeted dietary intervention could be harnessed in orchestrating a spectrum of immune-associated diseases.