Objective: To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants. M ethods: CUS scans from term infants with neonatal magnetic...Objective: To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants. M ethods: CUS scans from term infants with neonatal magnetic resonance imaging (MR I) evidence of neonatal infarction were reviewed. The scans were grouped by acqu isition time after birth: 1-3 days (early) or 4-14 days (late). Results: Brain MRI showed infarction in the territory of the middle cerebral artery in 43 of 4 7 infants, anterior cerebral artery in one, and posterior cerebral artery in thr ee. Twelve of the 47 had minor changes on MRI in the white matter in the contral ateral hemisphere, and four infants had bilateral infarctions. The early CUS sca ns were abnormal in 68%of the infants; the late CUS scans were abnormal in 87% . The late CUS scans were correct for laterality and site of lesion in 25/47 (53 %) infants. In six infants with smaller lesions of the cortical middle cerebral artery branch or lesions in the posterior cerebral artery territory, the CUS sc ans were persistently normal. Conclusion: Normal early CUS scans do not exclude a diagnosis of neonatal stroke, although most scans are abnormal. CUS scans perf ormed after day 3 were abnormal in 87%of infants. CUS scan findings were accura te for lesion laterality and site in 53%, and, in 34%, the scans showed abnorm ality strongly suggestive of infarction but not always site specific. For optima l prognostic information, infants with clinical histories or CUS scan findings s uggestive of infarction should have a neonatal brain MRI scan.展开更多
The authors report six neonates with enteroviral meningoencephalitis. Five infants presented with prolonged seizures, and one presented with systemic enteroviral disease. Cranial ultrasonography showed increased echog...The authors report six neonates with enteroviral meningoencephalitis. Five infants presented with prolonged seizures, and one presented with systemic enteroviral disease. Cranial ultrasonography showed increased echogenicity in the periventricular white matter, and MRI confirmed mild to severe white matter damage in all infants, which looked similar to periventricular leukomalacia. Two infants developed cerebral palsy: one was neurologically suspect at age 18 months, and three were developmentally normal.展开更多
文摘Objective: To evaluate the diagnostic accuracy of cranial ultrasound (CUS) for detection of neonatal arterial territory cerebral infarction in term infants. M ethods: CUS scans from term infants with neonatal magnetic resonance imaging (MR I) evidence of neonatal infarction were reviewed. The scans were grouped by acqu isition time after birth: 1-3 days (early) or 4-14 days (late). Results: Brain MRI showed infarction in the territory of the middle cerebral artery in 43 of 4 7 infants, anterior cerebral artery in one, and posterior cerebral artery in thr ee. Twelve of the 47 had minor changes on MRI in the white matter in the contral ateral hemisphere, and four infants had bilateral infarctions. The early CUS sca ns were abnormal in 68%of the infants; the late CUS scans were abnormal in 87% . The late CUS scans were correct for laterality and site of lesion in 25/47 (53 %) infants. In six infants with smaller lesions of the cortical middle cerebral artery branch or lesions in the posterior cerebral artery territory, the CUS sc ans were persistently normal. Conclusion: Normal early CUS scans do not exclude a diagnosis of neonatal stroke, although most scans are abnormal. CUS scans perf ormed after day 3 were abnormal in 87%of infants. CUS scan findings were accura te for lesion laterality and site in 53%, and, in 34%, the scans showed abnorm ality strongly suggestive of infarction but not always site specific. For optima l prognostic information, infants with clinical histories or CUS scan findings s uggestive of infarction should have a neonatal brain MRI scan.
文摘The authors report six neonates with enteroviral meningoencephalitis. Five infants presented with prolonged seizures, and one presented with systemic enteroviral disease. Cranial ultrasonography showed increased echogenicity in the periventricular white matter, and MRI confirmed mild to severe white matter damage in all infants, which looked similar to periventricular leukomalacia. Two infants developed cerebral palsy: one was neurologically suspect at age 18 months, and three were developmentally normal.
