期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
基于MRI影像组学预测胶质母细胞瘤MGMT基因启动子甲基化状态的应用 被引量:7
1
作者 魏炜 崔洛 +1 位作者 解立志 吴琼 《影像诊断与介入放射学》 2018年第3期179-184,共6页
目的在胶质母细胞瘤(GBM)患者中,O6-甲基鸟嘌呤-DNA甲基转移酶(O6-methylguanine-DNA methyltransferase,MGMT)基因启动子甲基化的状态决定了病人是否可从替莫唑胺化疗中获益,因此本文试图分析影像组学特征与MGMT基因启动子甲基化状态... 目的在胶质母细胞瘤(GBM)患者中,O6-甲基鸟嘌呤-DNA甲基转移酶(O6-methylguanine-DNA methyltransferase,MGMT)基因启动子甲基化的状态决定了病人是否可从替莫唑胺化疗中获益,因此本文试图分析影像组学特征与MGMT基因启动子甲基化状态的关联性以实现GBM术后个性化医疗。方法回顾性收集137例患者术前MRI影像并人工勾画ROI,随后在T_1WI增强序列上提取620个高维3D影像组学特征,并采用Pearson相关和LASSO回归进行特征选择,最后用Logistic回归进行MGMT甲基化状态分类预测。结果在内部验证集上的AUC为0.974,符合率91.2%,敏感度70.0%,特异度100.0%。结论研究结果表明,影像组学方法可在术前无创的预测胶质母细胞瘤患者MGMT基因启动子甲基化状态。 展开更多
关键词 影像组学 磁共振成像 胶质母细胞瘤 O6-甲基鸟嘌呤-DNA甲基转移酶 甲基化
下载PDF
BLE通信的移动跨平台考勤方法及系统应用 被引量:1
2
作者 周千明 崔洛 解建仓 《单片机与嵌入式系统应用》 2020年第5期33-36,75,共5页
针对当前企事业单位对成本低廉、识别精确的考勤管理方案的实际需求,提出一种轻量级、高效便捷的基于BLE通信的移动跨平台考勤方法。通过依托跨平台移动框架Flutter构建Android/iOS移动端APP,实现考勤用户注册、加密考勤二维码扫描与BL... 针对当前企事业单位对成本低廉、识别精确的考勤管理方案的实际需求,提出一种轻量级、高效便捷的基于BLE通信的移动跨平台考勤方法。通过依托跨平台移动框架Flutter构建Android/iOS移动端APP,实现考勤用户注册、加密考勤二维码扫描与BLE连接请求发起,采用基于CC2640R2F芯片的BLE数据透传模块作为Android/iOS移动端与PC端的桥接,PC端完成加密考勤二维码的生成、签到信息校验及考勤二维码的实时更新。应用实践表明,本文提出的解决方案切实可行,具有较高的实际应用价值。 展开更多
关键词 移动跨平台 Flutter框架 BLE通信 二维码 蓝牙5.0 数据透传模块
下载PDF
一种基于模式的界面生成方法 被引量:1
3
作者 崔洛 周千明 +1 位作者 魏炜 贺兴时 《计算机系统应用》 2020年第4期226-230,共5页
多设备环境下,应用程序在不同设备上用户界面的差异性导致了界面设计工作的重复和困难.应用界面模式,开发者可以脱离使用繁琐的底层控件生成用户界面的开发方法,专注于宏观的交互方案,从而为多设备界面生成问题提供一个可能的解.基于PL... 多设备环境下,应用程序在不同设备上用户界面的差异性导致了界面设计工作的重复和困难.应用界面模式,开发者可以脱离使用繁琐的底层控件生成用户界面的开发方法,专注于宏观的交互方案,从而为多设备界面生成问题提供一个可能的解.基于PLML,本文设计了一个设备无关的界面模式描述语言SPLML用于表示基于模式的界面元素信息,实现了不同平台上的界面模式生成框架UIPF用于支持界面自动化生成,并通过具体案例说明了该方案的可行性和有效性. 展开更多
关键词 界面模式 多设备界面 PLML 用户界面
下载PDF
Cryogenian and Ediacaran integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas
4
作者 Lang SUN Malik Muhammad Saud Sajid KHAN +13 位作者 Chuan YANG Zhixin SUN Bing PAN Shehryar AHMED Lanyun MIAO Weichen SUN Chunlin HU Xiaojuan SUN cui luo Bo CHEN Zongjun YIN Fangchen ZHAO Guoxiang LI Maoyan ZHU 《Science China Earth Sciences》 SCIE EI CAS CSCD 2024年第4期919-949,共31页
The complex evolutionary history of the Qinghai-Tibetan Plateau and its surrounding areas,including the continental blocks(Indian,Lhasa,South Qiangtang,Tarim,Olongbuluk,Central Qilian,Alxa,North China,Yangtze,Central ... The complex evolutionary history of the Qinghai-Tibetan Plateau and its surrounding areas,including the continental blocks(Indian,Lhasa,South Qiangtang,Tarim,Olongbuluk,Central Qilian,Alxa,North China,Yangtze,Central Iran and Oman)and the orogenic belts between them,has long been the frontier in Earth science research.The Cryogenian and Ediacaran strata are extensively distributed in these blocks.Specifically,relatively complete Cryogenian and Ediacaran successions have been discovered in Oman,Indian,Yangtze,and Tarim blocks,while only the Ediacaran successions have been reported in Iran,the South Qiangtang,Central Qilian,Alxa,and North China blocks.Based on previous studies together with the integration of new materials and advancement obtained through the Second Tibetan Plateau Scientific Expedition and Research,this review aims to synthesize a correlative stratigraphic framework of the representative Cryogenian and Ediacaran sequences from the Qinghai-Tibetan Plateau and its surrounding areas.Furthermore,the Cryogenian and Ediacaran biotas and major geological events in these areas are comprehensively discussed in aspects of current research status.The results indicate that,in general,Ediacaran fossils of each area exhibit distinct features in preservation and assemblage composition,but the typical late Ediacaran fossils Cloudina and Shaanxilithes have been reported from most of these areas.In addition to the two global Cryogenian glaciations,late Ediacaran glaciogenic deposits are extensively recorded in the areas within and around the northern QinghaiTibetan Plateau(including the North China,Alxa,Central Qilian,Olongbuluk,and Tarim blocks,and the North Qilian Accretionary Belt),as well as central and southern Iran.However,further research is required to determine the age,distribution,and origin of these late Ediacaran glaciogenic deposits.Meanwhile,the middle Ediacaran DOUNCE/Shuram Excursion is widely documented in the Qinghai-Tibetan Plateau and its surrounding areas.The available data show that,after the break-up of the Rodinia supercontinent,most of the continental blocks in the areas were located along the northern margin of East Gondwana and a few(such as North China)were located between the Gondwana and Laurentia.In general,the paleogeographic evolution of most of these blocks during the Cryogenian and Ediacaran remains disputatious,necessitating further research to resolve the controversies surrounding their paleogeographic reconstruction models during this critical time interval. 展开更多
关键词 Qinghai-Tibetan Plateau CRYOGENIAN EDIACARAN STRATIGRAPHY PALAEOGEOGRAPHY BIOTA GONDWANA
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部