NRBF2 has been identified as the fifth component of PI3KC3 complex and is required for maintaining the kinase activity to promote autophagy.However,the physiological and pathological roles of NRBF2are largely unknown.
基金supported by the China Ministry of Science and Technology grant(No.Mo ST-2017YFE0120100)The Science and Technology Development Fund,Macao SAR(Nos.024/2017/AMJ,0128/2019/A3)+2 种基金the University of Macao grant(NoMYRG2019-00129-ICMS)(to JHL)supported by GRF/HKBU(Nos.12101417,12100618)HMRF(Nos.17182541,17182551)(to ML)。
文摘NRBF2 has been identified as the fifth component of PI3KC3 complex and is required for maintaining the kinase activity to promote autophagy.However,the physiological and pathological roles of NRBF2are largely unknown.