Objective To explore the correlation between serum, heavy metal and semen quality in normal Chinese young menMethods This study was designed as a multi-center cross-sectional investigation. The subjects consisted of 5...Objective To explore the correlation between serum, heavy metal and semen quality in normal Chinese young menMethods This study was designed as a multi-center cross-sectional investigation. The subjects consisted of 562 male vomunteers who had undergone premarital physical examination in maternal and children health centers in 7 provinces in China. Results Results from Spearman rank correlation analysis (partial variable: region) show that serum lead and cadmium are negatively related to percentage of morphological normal sperm, but canonical correlation between semen quality and serum heavy metal are not significant. Canonical correlation analysis among the subjects from Guizhou shows cadmium is harmful to sperm morphology. In Henan, furthermore, results show lead and cadmium could negatively affect sperm viability and morphology. Conclusion Among all study subjects, canonical correlation between semen quality and serum heavy metal were not significant; however, results in some region showed serum cadmium and lead might be harmful to sperm quality.展开更多
Objective To understand the current semen quality status among Chinese young men and influential factors in China and to explore its evaluation index. Methods A total of 562 healthy male volunteers were recruited duri...Objective To understand the current semen quality status among Chinese young men and influential factors in China and to explore its evaluation index. Methods A total of 562 healthy male volunteers were recruited during their premarital examinations in seven provincials and municipal regions' MCH centers; descriptive and principal component analyses were used to analyze data.Results The findings show that semen volume (2. 61± 1. 10 mL), sperm density (64. 47× 34. 59× 106/mL), percentage of sperm forward progression (59. 89%± 17. 11%), percentage of sperm viability (77. 19% ± 11. 87%), and percentage of normal sperm morphology ( 78. 23% ± 9. 15% ). The first principal component function is Z1= -8.512 54 + 0. 001 35X1' + 0. 031 92X2'+0. 043 52X3'+ 0. 039 84X4', which is closely related to percentage of sperm viability (X3), percentage of sperm forward progression (X2), and percentage of normal sperm morphology (X4)The second principal component function is: Z2= 0. 491 92+ 0. 080 80X1- 0. 000 58X2-0. 005 10X3- 0. 018 07X4, which depends on the total sperm count (X1). Conclusion Only 42. 3% subjects meet all the common WHO standard of semen quality. The multiple analysis of Z1 showed that the highest Z1 are among subjects from Guizhou,workers, or town residents. Multiple analysis of Z2 showed that the older age when the subjects had the first sexual impulse, the longer period of sexual abstinence and more quantity of sperm they had; the more sexual activity subjects had, the less amount of sperm they had.展开更多
文摘Objective To explore the correlation between serum, heavy metal and semen quality in normal Chinese young menMethods This study was designed as a multi-center cross-sectional investigation. The subjects consisted of 562 male vomunteers who had undergone premarital physical examination in maternal and children health centers in 7 provinces in China. Results Results from Spearman rank correlation analysis (partial variable: region) show that serum lead and cadmium are negatively related to percentage of morphological normal sperm, but canonical correlation between semen quality and serum heavy metal are not significant. Canonical correlation analysis among the subjects from Guizhou shows cadmium is harmful to sperm morphology. In Henan, furthermore, results show lead and cadmium could negatively affect sperm viability and morphology. Conclusion Among all study subjects, canonical correlation between semen quality and serum heavy metal were not significant; however, results in some region showed serum cadmium and lead might be harmful to sperm quality.
文摘Objective To understand the current semen quality status among Chinese young men and influential factors in China and to explore its evaluation index. Methods A total of 562 healthy male volunteers were recruited during their premarital examinations in seven provincials and municipal regions' MCH centers; descriptive and principal component analyses were used to analyze data.Results The findings show that semen volume (2. 61± 1. 10 mL), sperm density (64. 47× 34. 59× 106/mL), percentage of sperm forward progression (59. 89%± 17. 11%), percentage of sperm viability (77. 19% ± 11. 87%), and percentage of normal sperm morphology ( 78. 23% ± 9. 15% ). The first principal component function is Z1= -8.512 54 + 0. 001 35X1' + 0. 031 92X2'+0. 043 52X3'+ 0. 039 84X4', which is closely related to percentage of sperm viability (X3), percentage of sperm forward progression (X2), and percentage of normal sperm morphology (X4)The second principal component function is: Z2= 0. 491 92+ 0. 080 80X1- 0. 000 58X2-0. 005 10X3- 0. 018 07X4, which depends on the total sperm count (X1). Conclusion Only 42. 3% subjects meet all the common WHO standard of semen quality. The multiple analysis of Z1 showed that the highest Z1 are among subjects from Guizhou,workers, or town residents. Multiple analysis of Z2 showed that the older age when the subjects had the first sexual impulse, the longer period of sexual abstinence and more quantity of sperm they had; the more sexual activity subjects had, the less amount of sperm they had.
