We present a simple and straightforward protocol for hydrochlorination of terminal arylalkynes to vinyl chlorides using hydrogen chloride under mild reaction conditions. This protocol does not involve any metal cataly...We present a simple and straightforward protocol for hydrochlorination of terminal arylalkynes to vinyl chlorides using hydrogen chloride under mild reaction conditions. This protocol does not involve any metal catalysts or additives. It is simple, inexpensive, and easy to prepare, and exhibits good reaction activity. The hydrochlorination proceeds smoothly to yield unique regioselective products via the Markovnikov addition rule.展开更多
基金supported by the National Nature Science Foundation of China(No.21063012)Changjiang Scholars and Innovative Research Team in University(No.IRT1161)Innovation Funds for distinguished young Scientists of Xinjiang Bingtuan(No.2011CD001)
基金financial support from the National Basic Research Program of China(973 Program,No.2012CB720300)the Applied Basic Research Program of Bingtuan(No.2015AG001)the High-level Talent Scientific Research Project of Shihezi University(No.RCZX201405)
文摘We present a simple and straightforward protocol for hydrochlorination of terminal arylalkynes to vinyl chlorides using hydrogen chloride under mild reaction conditions. This protocol does not involve any metal catalysts or additives. It is simple, inexpensive, and easy to prepare, and exhibits good reaction activity. The hydrochlorination proceeds smoothly to yield unique regioselective products via the Markovnikov addition rule.
