In their recent study published in Nature,Yuan and colleagues enlighten the role of histone lysine crotonylation(Kcr)in brain tumor biology.They report a novel lysine-dependent mechanism through which glioblastoma ste...In their recent study published in Nature,Yuan and colleagues enlighten the role of histone lysine crotonylation(Kcr)in brain tumor biology.They report a novel lysine-dependent mechanism through which glioblastoma stem cells modulate type I interferon(IFNα/IFNβ)signaling to create an immunosuppressive environment.展开更多
文摘In their recent study published in Nature,Yuan and colleagues enlighten the role of histone lysine crotonylation(Kcr)in brain tumor biology.They report a novel lysine-dependent mechanism through which glioblastoma stem cells modulate type I interferon(IFNα/IFNβ)signaling to create an immunosuppressive environment.