This paper compares two models predicting elastic and viscoelastic properties of large arteries.Models compared include a Kelvin(standard linear)model and an extended 2-term exponential linear viscoelastic model.Mode...This paper compares two models predicting elastic and viscoelastic properties of large arteries.Models compared include a Kelvin(standard linear)model and an extended 2-term exponential linear viscoelastic model.Models were validated against in-vitro data from the ovine thoracic descending aorta and the carotid artery.Measurements of blood pressure data were used as an input to predict vessel cross-sectional area.Material properties were predicted by estimating a set of model parameters that minimize the difference between computed and measured values of the cross-sectional area.The model comparison was carried out using generalized analysis of variance type statistical tests.For the thoracic descending aorta,results suggest that the extended 2-term exponential model does not improve the ability to predict the observed cross-sectional area data,while for the carotid artery the extended model does statistically provide an improved fit to the data.This is in agreement with the fact that the aorta displays more complex nonlinear viscoelastic dynamics,while the stiffer carotid artery mainly displays simpler linear viscoelastic dynamics.展开更多
基金supported in part(DVJ)by the Consejo Nacional de Ciencias y Tecnologia de Mexico(CONACYT)in part(HTB)by the US Air Force Office of Scientific Research under grant AFOSR-FA9550-08-1-0147+3 种基金by the National Institute of Al-lergy and Infectious Disease under grant NIAID 9R01AI071915-05in part(MAH)by the National Science Foundation under grant DMS-0636590by the National Insti-tutes of Health under grant NIH-AG-15768in part(MSO)by the National Science Foundation under grant DMS-0616597。
文摘This paper compares two models predicting elastic and viscoelastic properties of large arteries.Models compared include a Kelvin(standard linear)model and an extended 2-term exponential linear viscoelastic model.Models were validated against in-vitro data from the ovine thoracic descending aorta and the carotid artery.Measurements of blood pressure data were used as an input to predict vessel cross-sectional area.Material properties were predicted by estimating a set of model parameters that minimize the difference between computed and measured values of the cross-sectional area.The model comparison was carried out using generalized analysis of variance type statistical tests.For the thoracic descending aorta,results suggest that the extended 2-term exponential model does not improve the ability to predict the observed cross-sectional area data,while for the carotid artery the extended model does statistically provide an improved fit to the data.This is in agreement with the fact that the aorta displays more complex nonlinear viscoelastic dynamics,while the stiffer carotid artery mainly displays simpler linear viscoelastic dynamics.
