Carbon fiber reinforced plastics provide many excellent properties and are widely used in the aerospace industry.However,the existing composites autoclave process still faces difficulties such as high-energy consumpti...Carbon fiber reinforced plastics provide many excellent properties and are widely used in the aerospace industry.However,the existing composites autoclave process still faces difficulties such as high-energy consumption,uneven distribution of temperature field,complications of pressure transmission,and high cost,which limit their application in manufacturing of large complex composites components.In this study,the vibration treatment was introduced into the composites microwave curing process innovatively.On the basis of giving full play to the uniform heating characteristics of the microwave,the problems of a large number of internal defects and poor molding quality caused by the insufficient curing pressure have been solved.The results showed that the samples cured by the improved microwave process without external pressure had a few internal voids,excellent interface bonding conditions,and lower residual stress.Their properties were almost consistent with the samples prepared by the standard autoclave process,which provided a new method for the high-performance,efficient,safe,and low-cost manufacturing of large complex composites components.展开更多
Objective:To investigate the evolution of herbal medicine in treating tuberculosis(TB)and encourage anti-TB drug discovery and development.Methods:In this study,477 ancient traditional Chinese medicine formulae were c...Objective:To investigate the evolution of herbal medicine in treating tuberculosis(TB)and encourage anti-TB drug discovery and development.Methods:In this study,477 ancient traditional Chinese medicine formulae were collected from the Dictionary of Traditional Chinese Medicine Prescriptions and 172 modern Chinese medicine formulae(from 1986 to 2016)were collected by searching 4 databases:Wan Fang Data Knowledge Service Platform,China National Knowledge Infrastructure Database(CNKI),China Science and Technology Journal Database(VIP)and Chinese Bio-medical Literature and Retrieval System(Sino Med)in Chinese.We restricted the search to publications in Chinese.Further data analysis was done using the Traditional Chinese Medicine Inheritance Support System version 2 Software.Results:There were 425 herbs in the 477 ancient formulae and 257 herbs in the 172 modern formulae.Half of the top 30 herbs were shared by both modern and ancient prescriptions.They are Radix Ophiopogonis,Astragalus membranaceus,Fritillaria cirrhosa,Dried rehmannia glutinosa,Poria cocos,Angelica sinensis,Prepared rehmannia glutinosa,Platycodon Root,Radix paeoniae alba,Schisandra chinensis,Bighead atractylodes rhizome,Rhizoma anemarrhenae,Cortex lycii radicis and Radix Scutellariae.Only two groups of herbs with a high correlation coefficient were found in both modern and ancient prescriptions,the Dried rehmannia glutinosa with Radix ophiopogonis,and Radix ophiopogonis with Prepared rehmannia glutinosa.There were 9 and 15 core herb combinations in modern and ancient prescriptions,respectively,but no one was found simutaniously in both modern and ancient prescriptions.Conclusions:Although there were wide variations in the herb groups and herb combinations in the formulae,half of the top 30 herbs were found in both modern and ancient prescriptions.The core herb combinations in modern and ancient prescriptions could help us to improve the priscription for treatment of TB.展开更多
Background Currently, migration has become one of the risk factors of high burden of tuberculosis in China. This study was to explore the influence of mass migration on the dynamics of Mycobacterium （M.） tuberculosi...Background Currently, migration has become one of the risk factors of high burden of tuberculosis in China. This study was to explore the influence of mass migration on the dynamics of Mycobacterium （M.） tuberculosis in Beijing, the capital and an urban area of China.展开更多
基金Project(2018YFA0702800)supported by the National Key R&D Program of China。
文摘Carbon fiber reinforced plastics provide many excellent properties and are widely used in the aerospace industry.However,the existing composites autoclave process still faces difficulties such as high-energy consumption,uneven distribution of temperature field,complications of pressure transmission,and high cost,which limit their application in manufacturing of large complex composites components.In this study,the vibration treatment was introduced into the composites microwave curing process innovatively.On the basis of giving full play to the uniform heating characteristics of the microwave,the problems of a large number of internal defects and poor molding quality caused by the insufficient curing pressure have been solved.The results showed that the samples cured by the improved microwave process without external pressure had a few internal voids,excellent interface bonding conditions,and lower residual stress.Their properties were almost consistent with the samples prepared by the standard autoclave process,which provided a new method for the high-performance,efficient,safe,and low-cost manufacturing of large complex composites components.
基金Supported by National Natural Science Foundation of China(No.81871691)Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding(No.XMLX201812)。
文摘Objective:To investigate the evolution of herbal medicine in treating tuberculosis(TB)and encourage anti-TB drug discovery and development.Methods:In this study,477 ancient traditional Chinese medicine formulae were collected from the Dictionary of Traditional Chinese Medicine Prescriptions and 172 modern Chinese medicine formulae(from 1986 to 2016)were collected by searching 4 databases:Wan Fang Data Knowledge Service Platform,China National Knowledge Infrastructure Database(CNKI),China Science and Technology Journal Database(VIP)and Chinese Bio-medical Literature and Retrieval System(Sino Med)in Chinese.We restricted the search to publications in Chinese.Further data analysis was done using the Traditional Chinese Medicine Inheritance Support System version 2 Software.Results:There were 425 herbs in the 477 ancient formulae and 257 herbs in the 172 modern formulae.Half of the top 30 herbs were shared by both modern and ancient prescriptions.They are Radix Ophiopogonis,Astragalus membranaceus,Fritillaria cirrhosa,Dried rehmannia glutinosa,Poria cocos,Angelica sinensis,Prepared rehmannia glutinosa,Platycodon Root,Radix paeoniae alba,Schisandra chinensis,Bighead atractylodes rhizome,Rhizoma anemarrhenae,Cortex lycii radicis and Radix Scutellariae.Only two groups of herbs with a high correlation coefficient were found in both modern and ancient prescriptions,the Dried rehmannia glutinosa with Radix ophiopogonis,and Radix ophiopogonis with Prepared rehmannia glutinosa.There were 9 and 15 core herb combinations in modern and ancient prescriptions,respectively,but no one was found simutaniously in both modern and ancient prescriptions.Conclusions:Although there were wide variations in the herb groups and herb combinations in the formulae,half of the top 30 herbs were found in both modern and ancient prescriptions.The core herb combinations in modern and ancient prescriptions could help us to improve the priscription for treatment of TB.
基金This work was supported by the Beijing Natural Science Foundation （No. 5062016） and National Natural Science Foundation of China （No. 81273144 and No. 31070120）.Acknowledgment： We thank Dr. LI Liang for sharing the epidemiological information on TB in Beijing and Dr. WANG Xiao- bo and Dr. ZHOU Hui for assisting in VNTR typing.
文摘Background Currently, migration has become one of the risk factors of high burden of tuberculosis in China. This study was to explore the influence of mass migration on the dynamics of Mycobacterium （M.） tuberculosis in Beijing, the capital and an urban area of China.
