The Cosmonaut Sea is one of the less studied ecosystems in the Southern Hemisphere.Unlike other seas which were near to coastal regions,however,few studies exist on the top predators in this zone.From December 2019 to...The Cosmonaut Sea is one of the less studied ecosystems in the Southern Hemisphere.Unlike other seas which were near to coastal regions,however,few studies exist on the top predators in this zone.From December 2019 to January 2020,a survey of seabirds was carried out on the board icebreaker R/V Xuelong 2 in the Cosmonaut Sea and the Cooperation Sea.Twenty-three bird species were recorded.Antarctic petrel(Thalassoica antarctica),Antarctic prion(Pachyptila desolata),and Arctic tern(Sterna paradisaea)were the most abundant species.A total of about 37500 birds belonging to 23 species were recorded.Around 23%of the region had no record of birds.A large number of birds was recorded in 39°E-40°E,44°E-46°E and 59°E-60°E.Many areas,such as 33°E-35°E,39°E-41°E,44°E-46°E and 59°E-60°E show a great richness.More than two-thirds of seabirds(71%)were observed in the zone near the ocean front.The prediction of the distributions of the most dominant species Antarctic petrel also showed that the area near the ocean front region had an important ecological significance for seabirds.The results suggest that the distribution of seabirds in the Cosmonaut Sea is highly heterogenous.展开更多
目的了解生长停滞特异性蛋白6/Axl受体酪氨酸激酶(growth arrest specific protein 6/Axl receptor tyrosine kinase,Gas6/Axl)信号通路在胃肠道恶性肿瘤中的研究进展及未来展望。方法检索关于Gas6/Axl信号通路在胃肠道恶性肿瘤中研究...目的了解生长停滞特异性蛋白6/Axl受体酪氨酸激酶(growth arrest specific protein 6/Axl receptor tyrosine kinase,Gas6/Axl)信号通路在胃肠道恶性肿瘤中的研究进展及未来展望。方法检索关于Gas6/Axl信号通路在胃肠道恶性肿瘤中研究的相关文献并进行分析及总结。结果Gas6/Axl信号通路在胃肠道恶性肿瘤中异常上调与活化,导致细胞恶性增殖、侵袭、转移等,从而促进胃肠道恶性肿瘤的发生及发展。目前在胃肠道恶性肿瘤领域中,Gas6/Axl信号通路的研究主要涉及肿瘤血管生成、肿瘤耐药、间质上皮转化及肿瘤微环境。结论Gas6/Axl信号通路调控许多细胞生物过程以及其他下游效应,其异常表达从各个方面促进胃肠道恶性肿瘤的发生与发展。深入探究Gas6/Axl信号通路在胃肠道恶性肿瘤的作用,对寻找治疗胃肠道恶性肿瘤的新靶点具有重要意义。展开更多
基金financially supported by National Polar Special Program “Impact and Response of Antarctic Seas to Climate Change” (Grant nos. IRASCC2020-2022-05, IRASCC2020-2022-06)
文摘The Cosmonaut Sea is one of the less studied ecosystems in the Southern Hemisphere.Unlike other seas which were near to coastal regions,however,few studies exist on the top predators in this zone.From December 2019 to January 2020,a survey of seabirds was carried out on the board icebreaker R/V Xuelong 2 in the Cosmonaut Sea and the Cooperation Sea.Twenty-three bird species were recorded.Antarctic petrel(Thalassoica antarctica),Antarctic prion(Pachyptila desolata),and Arctic tern(Sterna paradisaea)were the most abundant species.A total of about 37500 birds belonging to 23 species were recorded.Around 23%of the region had no record of birds.A large number of birds was recorded in 39°E-40°E,44°E-46°E and 59°E-60°E.Many areas,such as 33°E-35°E,39°E-41°E,44°E-46°E and 59°E-60°E show a great richness.More than two-thirds of seabirds(71%)were observed in the zone near the ocean front.The prediction of the distributions of the most dominant species Antarctic petrel also showed that the area near the ocean front region had an important ecological significance for seabirds.The results suggest that the distribution of seabirds in the Cosmonaut Sea is highly heterogenous.
文摘目的了解生长停滞特异性蛋白6/Axl受体酪氨酸激酶(growth arrest specific protein 6/Axl receptor tyrosine kinase,Gas6/Axl)信号通路在胃肠道恶性肿瘤中的研究进展及未来展望。方法检索关于Gas6/Axl信号通路在胃肠道恶性肿瘤中研究的相关文献并进行分析及总结。结果Gas6/Axl信号通路在胃肠道恶性肿瘤中异常上调与活化,导致细胞恶性增殖、侵袭、转移等,从而促进胃肠道恶性肿瘤的发生及发展。目前在胃肠道恶性肿瘤领域中,Gas6/Axl信号通路的研究主要涉及肿瘤血管生成、肿瘤耐药、间质上皮转化及肿瘤微环境。结论Gas6/Axl信号通路调控许多细胞生物过程以及其他下游效应,其异常表达从各个方面促进胃肠道恶性肿瘤的发生与发展。深入探究Gas6/Axl信号通路在胃肠道恶性肿瘤的作用,对寻找治疗胃肠道恶性肿瘤的新靶点具有重要意义。
