目的探讨当前基于疾病诊断相关分类(disease diagnosis related Classification,DRGs)的病案编码质量,并针对性提出质量监测建议,对比质量监测前后病案编码质量的差异,以期为提高医院病案编码工作的质量和效率提供理论基础与参考借鉴。...目的探讨当前基于疾病诊断相关分类(disease diagnosis related Classification,DRGs)的病案编码质量,并针对性提出质量监测建议,对比质量监测前后病案编码质量的差异,以期为提高医院病案编码工作的质量和效率提供理论基础与参考借鉴。方法随机选择2018年12月—2020年12月佛山复星禅诚医院出院患者病案作为研究对象,其中2018年12月—2019年12月为干预前,共计1820份,2020年1—12月为干预后,共计1660份。统计干预前病案编码的准确性,分析编码错误原因。此外,为进一步提高病案编码工作质量,本研究针对性提出加大质控检查、建立奖惩制度以及增强人员培训等质量监测对策,并对比质量监测前后病案编码质量的差异。结果在核查的干预前的1820份病案中,诊断编码正确的病案数是1616份,错误的病案数为204份,正确率仅为88.8%。其中,涉及到手术治疗的病案数有1516份,手术编码正确率为86.9%(1318/1516)。此外,在实施针对性质量监测后,诊断编码正确率以及手术编码正确率均有显著提高,差异有统计学意义(P<0.05),错编、漏填(编码问题)以及选错、漏填(医师填写问题)等现象发生率显著降低,差异有统计学意义(P<0.05)。结论通过贯彻落实加大质控检查、建立奖惩制度以及增强人员培训等质量监测手段,显著提高了病案编码的规范性及质量。展开更多
Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which...Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF展开更多
文摘目的探讨当前基于疾病诊断相关分类(disease diagnosis related Classification,DRGs)的病案编码质量,并针对性提出质量监测建议,对比质量监测前后病案编码质量的差异,以期为提高医院病案编码工作的质量和效率提供理论基础与参考借鉴。方法随机选择2018年12月—2020年12月佛山复星禅诚医院出院患者病案作为研究对象,其中2018年12月—2019年12月为干预前,共计1820份,2020年1—12月为干预后,共计1660份。统计干预前病案编码的准确性,分析编码错误原因。此外,为进一步提高病案编码工作质量,本研究针对性提出加大质控检查、建立奖惩制度以及增强人员培训等质量监测对策,并对比质量监测前后病案编码质量的差异。结果在核查的干预前的1820份病案中,诊断编码正确的病案数是1616份,错误的病案数为204份,正确率仅为88.8%。其中,涉及到手术治疗的病案数有1516份,手术编码正确率为86.9%(1318/1516)。此外,在实施针对性质量监测后,诊断编码正确率以及手术编码正确率均有显著提高,差异有统计学意义(P<0.05),错编、漏填(编码问题)以及选错、漏填(医师填写问题)等现象发生率显著降低,差异有统计学意义(P<0.05)。结论通过贯彻落实加大质控检查、建立奖惩制度以及增强人员培训等质量监测手段,显著提高了病案编码的规范性及质量。
基金This work was supported in part by the National Natural Science Foundation of China (Grant No. 39970814).
文摘Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF
