The Development Characteristics and Distribution Predictions of the Paleogene Coal-measure Source Rock in the Qiongdongnan Basin,Northern South China Sea

There are known to be enormous Cenozoic coal-type oil and gas resources located in the basins of the South China Sea,among which the Paleogene coal-measure source rock are one of the main source rock.In order to more effectively analyze the distribution laws of coal-measure source rock in marginal sea basins and guide coal-type oil and gas explorations,the Oligocene coal-measure source rock in the Qiongdongnan Basin were selected as examples in order to systematically analyze the types,development characteristics,control factors,and distribution prediction methods of coalmeasure source rock in marginal sea basins.The Qiongdongnan Basin is located in the northern region of the South China Sea.Previous explorations of the area have determined that the Oligocene coal-measure source rock in the Qiongdongnan Basin have typical"binary structures",which include coal seams and terrigenous marine mudstone.Among those,the terrigenous marine mudstone has been found to greatly expand the scope of the coal-measure source rock.In addition,the coal seams which have been exposed by drilling have been observed to have the characteristics of thin single layer thickness,many layers,and poor stability.Meanwhile,the terrigenous marine mudstone has the characteristics of large thickness and wide distribution.The development of coal-measure source rock is known to be controlled by many factors,such as paleoclimate and paleobotany condition,paleo-structure and topography,paleo-geography,rise and fall of base level,and so on.In accordance with the comprehensive analyses of various control factors of coal-measure source rock,and the changes in water body energy in sedimentary environments,a genetic model of the"energy belt"for the development and distribution of coal-measure source rock was proposed.Also,the development and distribution characteristics of coalmeasure source rock in different types of energy belts were clarified.Then,based on the development and distribution characteristics of coal-measure source rock and their controlling factors,prediction methods of the distribution ranges of coal-measure source rock were proposed from both qualitative and(semi-)quantitative aspects.That is to say,a method for(semi-)quantitative predictions of the distribution ranges of coal-bearing intervals based on model wave impedance inversion and neural network wave impedance inversion,along with a method for(semi-)quantitative predictions of the distribution ranges of terrigenous marine mudstone based on topographical slopes,were introduced in this study.

鄂尔多斯盆地南部延安组巨厚煤层内古气候旋回分析

煤是一种气候敏感型沉积物,为了查明煤层中蕴含的古气候信息及其演化控制因素,选取鄂尔多斯盆地南部延安组一段4号巨厚煤层为研究对象,通过系统密集采样,并测试煤的有机显微组分含量、主量和微量元素及有机质稳定碳同位素含量。利用煤岩显微组分、特征元素和碳同位素等方法,分别在该巨厚煤层内部识别出4个温湿-干热交替的古气候旋回,且识别结果非常一致;该结果与前人在邻区4号煤层中使用古植物含量系数法的识别结果也非常吻合。在此基础上,与前人在该巨厚煤层中识别出的米兰科维奇旋回信息进行比较,综合分析认为该巨厚煤层中古气候旋回的发育与演化主要受到天体轨道参数中偏心率长周期的控制。研究成果证实了方法的可靠性,阐明了古气候旋回的成因机制。

姜汁水凝胶穴位贴敷对哮喘大鼠辅助性T细胞2细胞因子的调节作用

目的:制备Fe_(3)O_(4)/N-异丙基丙烯酰胺(PNIPAM)新型穴位敷贴剂型,检测其性能,并应用于哮喘模型的穴位贴敷疗法,探讨该疗法对哮喘大鼠辅助性T细胞2细胞因子调节作用。方法:制备Fe_(3)O_(4)/PNIPAM复合水凝胶并测定升温性能,电镜下观察内部结构,检验细胞毒性。将32只SD大鼠随机分为4组,分别为正常组、模型组、激光姜汁组、激素组,每组8只。除正常组外,其余组制备哮喘模型,激光姜汁组姜汁水凝胶贴敷大椎穴5 min并808 nm激光照射控制药物释放;激素组采用地塞米松1.2 mg/kg腹腔注射;均为隔日1次。观察大鼠一般状态;ELESA检测支气管肺泡灌洗液(BALF)中免疫球蛋白E(IgE)、白介素(IL)-4、IL-13的表达;HE染色检测肺组织病理情况。结果:2.0 Fe_(3)O_(4)/PNIPAM具有疏松孔状结构,良好的吸热升温性能,且无细胞毒性。与模型组比较,激光姜汁组可显著改善哮喘大鼠的行为学评分(P<0.01);与模型组和激素组比较,激光姜汁组显著降低BALF中IgE的含量,降低IL-4、IL-13的表达(P<0.01,P<0.05)。结论:Fe_(3)O_(4)/PNIPAM无细胞毒性,具有良好的疏松孔状结构可负载药物,具有良好的吸热升温性能可控制药物释放,可作为新型穴位贴敷制剂。姜汁水凝胶穴位贴敷疗法可通过降低BALF中IgE、IL-4、IL-13的表达缓解哮喘的发作症状。