目的系统评价奈达铂对比顺铂联合氟尿嘧啶治疗食管癌的疗效和安全性。方法计算机检索PubMed、EMbase、Web of Science、The Cochrane Library、中国知网、万方、维普和中国生物医学文献数据库,搜集关于奈达铂联合氟尿嘧啶对比顺铂联合...目的系统评价奈达铂对比顺铂联合氟尿嘧啶治疗食管癌的疗效和安全性。方法计算机检索PubMed、EMbase、Web of Science、The Cochrane Library、中国知网、万方、维普和中国生物医学文献数据库,搜集关于奈达铂联合氟尿嘧啶对比顺铂联合氟尿嘧啶治疗食管癌的随机对照研究,检索时限均为建库至2021年1月。采用RevMan 5.4软件进行Meta分析。结果最终纳入12个随机对照研究,共含744例患者。Meta分析结果显示,奈达铂组的总有效率优于顺铂组(P<0.05);在毒副作用方面,奈达铂组恶心呕吐、腹泻、肾功能损伤发生率比顺铂组低(P<0.05),但白细胞减少、血红蛋白降低发生率较顺铂组高(P<0.05)。两组肝功能损伤和血小板减少发生率差异无统计学意义(P>0.05)。结论奈达铂联合氟尿嘧啶比顺铂联合氟尿嘧啶治疗食管癌更有优势,并且恶心呕吐以及腹泻的发生率更低,对肾功能的损害也更小。展开更多
Since its advent in the early 1920s, Western Marxism has undergone a torturous process from anti-liberalism to virtually liberalism. The main theoretical deficiency behind this process is the over-estimation of Marx＇...Since its advent in the early 1920s, Western Marxism has undergone a torturous process from anti-liberalism to virtually liberalism. The main theoretical deficiency behind this process is the over-estimation of Marx＇s cultural critique of capitalism. As his economic research gradually deepened, Marx＇s dual critique of capitalism from economic and cultural perspectives matured. When the leading proponents of Soviet Marxism gave prominence to Marx＇s economic critique, as circumstances required, they and some key figures in the Second International misread his theory with emphasis on economic determinism. In contrast, Georg Luk^cs and most Western Marxists proceeded to develop a Marxian cultural critique with the consequence that his economic research being marginalized. Without the counterbalance of a continuous and consistent economic theory to challenge a confident international capitalism, cultural critique is consequently reorganized in confluence with liberalism, which is centered on an individual ontology. Re-excavating Marxian dual critical theory may help Western Marxism escape the dilemma.展开更多
文摘Since its advent in the early 1920s, Western Marxism has undergone a torturous process from anti-liberalism to virtually liberalism. The main theoretical deficiency behind this process is the over-estimation of Marx＇s cultural critique of capitalism. As his economic research gradually deepened, Marx＇s dual critique of capitalism from economic and cultural perspectives matured. When the leading proponents of Soviet Marxism gave prominence to Marx＇s economic critique, as circumstances required, they and some key figures in the Second International misread his theory with emphasis on economic determinism. In contrast, Georg Luk^cs and most Western Marxists proceeded to develop a Marxian cultural critique with the consequence that his economic research being marginalized. Without the counterbalance of a continuous and consistent economic theory to challenge a confident international capitalism, cultural critique is consequently reorganized in confluence with liberalism, which is centered on an individual ontology. Re-excavating Marxian dual critical theory may help Western Marxism escape the dilemma.
