The Qinghai-Tibet Plateau is one of the major sandy desertification regions of China. Based on the recent investigation on sandy desertification, this paper analyses the status such as the type, area, distribution and...The Qinghai-Tibet Plateau is one of the major sandy desertification regions of China. Based on the recent investigation on sandy desertification, this paper analyses the status such as the type, area, distribution and damage of sandy land desertification in the plateau. Through the analysis on the factors affecting sandy desertification in the region’s natural and socio-economic systems as well as the processes and their interrelations, it can be concluded that sandy desertification in the Qinghai-Tibet Plateau resulted from the combined actions of normal natural sand drift processes, natural sandy desertification processes caused by climatic changes and man-made sandy desertification caused by improper human activities. In addition, it also predicts the possible developmental trend including the increase in desertification area and the enhancement in desertification developmental degree with the exacerbation of the complex processes, and finally puts forward some strategic suggestions to combat sandy desertification in the coming years.展开更多
We tried to develop an efficient strategy to isolate geniposide from Gardenia fruit and use it to treat chronic pain. Eight extraction solvents and three extraction methods were respectively compared with each other f...We tried to develop an efficient strategy to isolate geniposide from Gardenia fruit and use it to treat chronic pain. Eight extraction solvents and three extraction methods were respectively compared with each other for the efficiency of geniposide extraction from Gardenia fruit. Extraction with 80% ethanol under reflux was found to give the highest yield of geniposide. Orthogonal experiment was conducted to optimize the reflux conditions and the optimal conditions are a mass（of Gardeniajasminoides Ellis powder） to volume（of solvent, 80% ethanol） ratio of 1：7 and reflux twice for 60 rain each. The geniposide obtained by the reflux method was tested on the rats with chronic constriction injury（CCI） for pain relief. The results show that geniposide can enhance pain threshold and relieve pain via repressing tumor necrosis factor-a（TNF-a） expression in either ipsilateral or contralateral dorsal root gan- glion（DRG） cells. These results suggest that geniposide treatement may be an effective clinical method to relieve pain based on the mechanism of molecular biology at DRG due to nerve injury.展开更多
基金Underthe auspices ofthe K ey ProjectofScience and Technology B ureau ofTibetA utonom ous R egion
文摘The Qinghai-Tibet Plateau is one of the major sandy desertification regions of China. Based on the recent investigation on sandy desertification, this paper analyses the status such as the type, area, distribution and damage of sandy land desertification in the plateau. Through the analysis on the factors affecting sandy desertification in the region’s natural and socio-economic systems as well as the processes and their interrelations, it can be concluded that sandy desertification in the Qinghai-Tibet Plateau resulted from the combined actions of normal natural sand drift processes, natural sandy desertification processes caused by climatic changes and man-made sandy desertification caused by improper human activities. In addition, it also predicts the possible developmental trend including the increase in desertification area and the enhancement in desertification developmental degree with the exacerbation of the complex processes, and finally puts forward some strategic suggestions to combat sandy desertification in the coming years.
基金Supported by the Natural Science Foundation of Jilin Province, China（No.20125059）.
文摘We tried to develop an efficient strategy to isolate geniposide from Gardenia fruit and use it to treat chronic pain. Eight extraction solvents and three extraction methods were respectively compared with each other for the efficiency of geniposide extraction from Gardenia fruit. Extraction with 80% ethanol under reflux was found to give the highest yield of geniposide. Orthogonal experiment was conducted to optimize the reflux conditions and the optimal conditions are a mass（of Gardeniajasminoides Ellis powder） to volume（of solvent, 80% ethanol） ratio of 1：7 and reflux twice for 60 rain each. The geniposide obtained by the reflux method was tested on the rats with chronic constriction injury（CCI） for pain relief. The results show that geniposide can enhance pain threshold and relieve pain via repressing tumor necrosis factor-a（TNF-a） expression in either ipsilateral or contralateral dorsal root gan- glion（DRG） cells. These results suggest that geniposide treatement may be an effective clinical method to relieve pain based on the mechanism of molecular biology at DRG due to nerve injury.
