Analysis of the Factors Influencing Urban Size on Air Concentrations of Particulate Matter PM_(2.5)and PM_(10)in China

In the construction of resilient cities,regional air pollution prevention plays a pivotal role.Building on the previous research experience,the relationship between air pollution concentration and urban size exhibits a sublinear allometric growth pattern.To identify effective strategies for mitigating particulate matter air pollution,this study quantitatively explored 6 variables influencing urbanization in China’s cities and established an allometry model.Empirical analysis was conducted using data from 293 prefecturelevel cities and 1,827 county-level cities to examine the relationship between annual concentrations of fine particulate matter PM_(2.5) and PM_(10) in the atmosphere.①The findings of this study provided partial validation for the Kuznets curve and demonstrated a reverse‘U’-shaped association between urbanization and levels of PM_(2.5) and PM_(10) pollution.②By partitioning the Hu Huanyong line,this study identified the spatial distribution pattern of PM_(2.5) and PM_(10).In central and western regions,as urban size expands,inhalable particle concentrations tended to increase further;whereas in the southeast region,inhalable particle concentrations gradually decreased and stabilized after a certain threshold of urban scale expansion was reached.Among the factors influencing urban size,green coverage within built-up areas exerted the most significant impact on both PM_(2.5) and PM_(10) concentrations,followed by the extent of built-up areas and the scale of secondary industries.This study presented an effective strategy for reconciling conflicts between urban expansion and air pollution management,while concurrently promoting resilient cities characterized by high levels of modernization and superior quality.

健脾化湿方联合聚焦超声治疗脾虚湿滞型子宫颈上皮内瘤变的临床效果

目的 观察健脾化湿方联合聚焦超声治疗脾虚湿滞型子宫颈上皮内瘤变(CIN)患者的临床效果及对淋巴细胞亚群的影响。方法 选取2019年8月—2022年8月临沂市中心医院收治的脾虚湿滞型CIN患者64例,根据随机数字表法分为观察组和对照组,每组32例。对照组采用单纯海扶高强度聚焦超声治疗,观察组在对照组基础上加用健脾化湿方治疗,2组均治疗3个月。比较2组患者临床疗效和中医证候疗效,治疗前后人乳头瘤病毒(HPV)阴性率,T细胞亚群、NK细胞和B淋巴细胞表达。结果 观察组患者临床总有效率为90.63%,高于对照组的62.50%(χ^(2)=7.053,P=0.008);观察组患者中医证候总有效率为84.38%,高于对照组的56.25%(χ^(2)=6.063,P=0.014)。治疗3个月后,观察组HPV阴性率为46.87%,高于对照组的21.87%(χ^(2)=4.433,P=0.035);观察组患者CD3^(+)、CD4^(+)较治疗前升高,2组B淋巴细胞较治疗前降低,观察组治疗后CD3^(+)、CD8^(+)高于对照组,B淋巴细胞低于对照组(P<0.05或P<0.01),对照组CD3^(+)、CD4^(+)、CD8^(+)与2组CD4^(+)/CD8^(+)、NK细胞治疗前后比较差异无统计学意义(P>0.05)。结论 健脾化湿方联合聚焦超声治疗脾虚湿滞型CIN患者的临床疗效、中医证候改善效果显著,可平衡淋巴细胞亚群比例,改善机体免疫功能。