The British government initiated the concept of low-carbon economy in its 2003 White Paper on energy,which constituted an economic model for higher economic output with low natural resource consumption and low environ...The British government initiated the concept of low-carbon economy in its 2003 White Paper on energy,which constituted an economic model for higher economic output with low natural resource consumption and low environmental pollution.展开更多
As an essential component of the immune system,T lymphocytes play an indispensable role in fighting bacteria or viruses and killing tumor cells.T cell activation undergoes an orderly and complex process that criticall...As an essential component of the immune system,T lymphocytes play an indispensable role in fighting bacteria or viruses and killing tumor cells.T cell activation undergoes an orderly and complex process that critically relies on T cell antigen receptor(TCR)signaling,which requires an orchestrated interplay of receptors,receptor-associated factors,kinases,and transcription factors,together termed TCR signalosome.Although the intracellular signaling cascade has been extensively studied,exactly how membrane TCR activation leads to intracellular signaling has remained elusive.展开更多
文摘The British government initiated the concept of low-carbon economy in its 2003 White Paper on energy,which constituted an economic model for higher economic output with low natural resource consumption and low environmental pollution.
文摘As an essential component of the immune system,T lymphocytes play an indispensable role in fighting bacteria or viruses and killing tumor cells.T cell activation undergoes an orderly and complex process that critically relies on T cell antigen receptor(TCR)signaling,which requires an orchestrated interplay of receptors,receptor-associated factors,kinases,and transcription factors,together termed TCR signalosome.Although the intracellular signaling cascade has been extensively studied,exactly how membrane TCR activation leads to intracellular signaling has remained elusive.