Jujube is one of the most produced dried fruits in China,and it is also a traditional Chinese medicine that enhances immunity and has anti-cancer activity.Jujube fruit is rich in phenolic compounds,but few reports are...Jujube is one of the most produced dried fruits in China,and it is also a traditional Chinese medicine that enhances immunity and has anti-cancer activity.Jujube fruit is rich in phenolic compounds,but few reports are available on its biological activities.To evaluate the biological activities of the phenolic compounds in dried jujube fruit,the composition and content of metabolites in dried jujube fruit were determined by metabolomics,and the antibacterial and anticancer activities of the phenolic compounds were analyzed in dried jujube fruit.The results showed that 463 compounds were identified in dried‘Junzao’fruit,including 102 phenolic compounds.The in vitro activity test showed that the jujube phenolic metabolites had extensive antibacterial effects and caused disruption and nuclear sclerosis of hepatocellular carcinoma(HepG2)cells.Canonical correlation analysis showed that total phenolic content,quercetin-3-rutinose,and procyanidin B1 were the main active antibacterial and anticancer components.The study provides data supporting the application of dried jujube fruit in the development of functional foods,pharmaceuticals and cosmetics.展开更多
A new type of wave containing quasi-static part is found and studied. Characteristics of this wave are analyzed, and the theoretical analysis is consistent with the numerical calculation.
基金supported by The National Key Research and Development Program of China(2018YFD1000607)National Natural Science Foundation of China(32171839 and 32101564)The earmarked fund of Xinjiang Jujube Industrial Technology System(XJCYTX-01).
文摘Jujube is one of the most produced dried fruits in China,and it is also a traditional Chinese medicine that enhances immunity and has anti-cancer activity.Jujube fruit is rich in phenolic compounds,but few reports are available on its biological activities.To evaluate the biological activities of the phenolic compounds in dried jujube fruit,the composition and content of metabolites in dried jujube fruit were determined by metabolomics,and the antibacterial and anticancer activities of the phenolic compounds were analyzed in dried jujube fruit.The results showed that 463 compounds were identified in dried‘Junzao’fruit,including 102 phenolic compounds.The in vitro activity test showed that the jujube phenolic metabolites had extensive antibacterial effects and caused disruption and nuclear sclerosis of hepatocellular carcinoma(HepG2)cells.Canonical correlation analysis showed that total phenolic content,quercetin-3-rutinose,and procyanidin B1 were the main active antibacterial and anticancer components.The study provides data supporting the application of dried jujube fruit in the development of functional foods,pharmaceuticals and cosmetics.
文摘A new type of wave containing quasi-static part is found and studied. Characteristics of this wave are analyzed, and the theoretical analysis is consistent with the numerical calculation.
