High resolution optical endoscopes are increasingly used in diagnosis of various medical condi-tions of internal organs,such as the cervix and gastrointestinal(GI)tracts,but they are too expensive for use in resource ...High resolution optical endoscopes are increasingly used in diagnosis of various medical condi-tions of internal organs,such as the cervix and gastrointestinal(GI)tracts,but they are too expensive for use in resource poor settings.On the other hand,smartphones with high resolution cameras and Internet access have become more affordable,enabling them to difuse into most rural areas and developing countries in the past decade.In this paper,we describe a smartphone microendoscope that can take fuorescence images with a spatial resolution of 3.1 pum.Images collected from ex vivo,in vnitro and in vivo samples using the device are also presented.The compact and cost-effective smart phone microendosoope may be envisaged as a powerful tool for detecting pre cancerous lesions of internal organs in low and middle income countries(LMICs).展开更多
文摘High resolution optical endoscopes are increasingly used in diagnosis of various medical condi-tions of internal organs,such as the cervix and gastrointestinal(GI)tracts,but they are too expensive for use in resource poor settings.On the other hand,smartphones with high resolution cameras and Internet access have become more affordable,enabling them to difuse into most rural areas and developing countries in the past decade.In this paper,we describe a smartphone microendoscope that can take fuorescence images with a spatial resolution of 3.1 pum.Images collected from ex vivo,in vnitro and in vivo samples using the device are also presented.The compact and cost-effective smart phone microendosoope may be envisaged as a powerful tool for detecting pre cancerous lesions of internal organs in low and middle income countries(LMICs).