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超声乳化联合房角黏连分离术与小梁切除术治疗APACG的疗效比较 被引量:5
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作者 邓水凤 廖锐 +6 位作者 李君霞 戴丹 李文涛 张碧玉 周灵 卓业鸿 朱颖婷 《国际眼科杂志》 CAS 北大核心 2021年第6期946-951,共6页
目的:对比分析原发性急性闭角型青光眼(APACG)合并早期白内障患者行白内障超声乳化联合房角黏连分离术(GSL+PPI术)及小梁切除术后的生活质量并分析相关因素。方法:前瞻性随机性病例对照研究。将符合纳入标准的APACG患者分为A(PPI+GSL术... 目的:对比分析原发性急性闭角型青光眼(APACG)合并早期白内障患者行白内障超声乳化联合房角黏连分离术(GSL+PPI术)及小梁切除术后的生活质量并分析相关因素。方法:前瞻性随机性病例对照研究。将符合纳入标准的APACG患者分为A(PPI+GSL术组,29例)、B(小梁切除术组,30例)两组,术后随访6mo,采用NEI-VFQ-25量表评估生活质量,同时记录患者眼压、最佳矫正视力(BCVA)、返院复查频率及基本信息。结果:术后6mo,两组眼压均较术前降低,A组BCVA较术前明显改善(均P<0.05),B组手术前后BCVA无明显差异(P>0.05),且B组复诊频率高于A组(P<0.05)。两组术后NEI-VFQ-25量表评分均较术前增高(均P<0.05),与B组比较,A组术后总体视觉、眼痛、远距离工作、社交功能、角色限制等方面的生活质量评分更高,且A组术后生活质量评分提高的幅度较B组更高(P<0.05),其与A组术后BCVA改善及复查频率较少有关(R2=0.48,F=5.00,P<0.05)。结论:与小梁切除术相比,PPI+GSL术后APACG合并早期白内障患者能获得更好的生活质量。 展开更多
关键词 原发性急性闭角型青光眼 白内障 白内障超声乳化联合房角黏连分离术 小梁切除术 生活质量
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miR-128-3p靶向Lin28B增加肝癌细胞对奥沙利铂的敏感性 被引量:2
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作者 夏如冰 王红英 +4 位作者 戴丹 董陶明 汪和平 邹思璐 张健 《世界华人消化杂志》 CAS 2018年第30期1748-1757,共10页
目的研究miR-128-3p与肝癌(hepatocellular carcinoma,HCC)细胞对奥沙利铂敏感性的影响,并探讨其作用机制.方法采用qRT-PCR法检测人正常肝细胞HL-7702、HCC细胞BEL-7402和Hep-3B中miR-128-3p、Lin28B的表达;将对数生长期的HCC细胞BEL-7... 目的研究miR-128-3p与肝癌(hepatocellular carcinoma,HCC)细胞对奥沙利铂敏感性的影响,并探讨其作用机制.方法采用qRT-PCR法检测人正常肝细胞HL-7702、HCC细胞BEL-7402和Hep-3B中miR-128-3p、Lin28B的表达;将对数生长期的HCC细胞BEL-7402、Hep-3B随机分成miR-128-3pmimics组(转染miR-128-3Pmimics)、miR-NC组(未转染细胞)、Lin28B-3'UTR WT组(载体psiCHECK2-Lin28B-3'UTR WT和miR-128-3p共转染)、Lin28B-3'UTRMUT组(载体psiCHECK2-Lin28B-3'UTRMUT和miR-NC共转染)和miR-128-3p+Lin28B组(miR-128-3p和Lin28B共转染)、si-Lin28B组(转染si-Lin28B)和si-NC组(转染沉默对照),均以脂质体转染.采用MTT法检测各组细胞的存活率和活力; Western Blot检测各组细胞的蛋白表达.结果与人正常肝细胞相比, HCC细胞BEL-7402和Hep-3B中miR-128-3p的表达较显著降低(P<0.01), Lin28B的表达较显著升高(P<0.01),且过表达miR-128-3p、沉默Lin28B均可抑制HCC细胞增殖,促进凋亡,增加HCC细胞对奥沙利铂的敏感性.Lin28B为mi R-128-3p的靶标,且回补Lin28B可逆转mi R-128-3p增加HCC细胞对奥沙利铂敏感性的作用.结论miR-128-3p可增加HCC细胞对奥沙利铂的敏感性,其作用机制可能与靶向Lin28B有关,提示miR-128-3p可作为抗奥沙利铂耐药性的潜在靶点. 展开更多
关键词 miR-128-3p Lin28B 奥沙利铂 肝癌细胞
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Surfactant-assisted fabrication of graphene frameworks endowing epoxy composites with superior thermal conductivity 被引量:2
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作者 Fan Zhang Chen Ye +9 位作者 Wen dai Le Lv Qilong Yuan Kuan W.A.Chee Ke Yang Nan Jiang Cheng-Te Lin Zhaolin Zhan dan dai He Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2020年第1期244-248,共5页
With the rapid growth in electronic device performance,there has been an increasing demand for thermally conductive polymer composites to handle the thermal management issue,thus contributing to the great importance t... With the rapid growth in electronic device performance,there has been an increasing demand for thermally conductive polymer composites to handle the thermal management issue,thus contributing to the great importance to develop the graphene framework,which is evaluated as the most promising reinforcements for enhancing the thermal conductivity of polymer.Vacuum filtration is a common method to fabricate graphene framework,whereas,it is available to prepare a framework with centimeter-scale thickness by filtrating the graphene-water dispersion,due to the fact of sample cracking caused by the mismatch of surface tension between graphene and water.In this work,a surfactantassisted strategy was proposed by adjusting the surface tension of the water close to that of graphene first,then performing a conventional filtration process,to fabricate graphene framework.As a result,a thick graphene framework(thickness:3 cm)was successfully prepared,and after embedding into epoxy,the framework endows the composite(13.6 wt%)with a high in-plane thermal conductivities of12.4 W/mK,which is equivalent to≈64 times higher than that of neat epoxy.Our method is simple and compatible with the conventional filtration process,suggesting great potential for the mass-production of graphene framework to meet the practical application requirements. 展开更多
关键词 Graphene framework SURFACTANT Vacuum filtration Thermal conductivity Polymer composite
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Hip-mounted electromagnetic generator to harvest energy from human motion 被引量:1
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作者 dan dai Jing LIU 《Frontiers in Energy》 SCIE CSCD 2014年第2期173-181,共9页
A type of electromagnetic hip-mounted generator (EHG) is proposed to harvest energy from human hip motion to generate electricity. Based on the law of electromagnetic induction, the EHG generator can convert the kin... A type of electromagnetic hip-mounted generator (EHG) is proposed to harvest energy from human hip motion to generate electricity. Based on the law of electromagnetic induction, the EHG generator can convert the kinetic power of the thigh swing into electrical energy during walking or running. To demonstrate the feasibility of the present method, a prototype of the EHG has been designed and fabricated. A theoretical analysis has been conducted to interpret the working behavior of this prototype. In addition, the performance of the system has been experimentally tested through a rotary motor and human body motion. When driven by the rotary motor at a rotation speed of 100 r/rain, the open-circuit voltage of this prototype is 2.5 V. Further, a maximum open-circuit voltage of approximately 1 V and a maximum output power of 284 μW could be produced respectively when walking with an EHG at a speed of 1.47 m/s. This handy renewable energy technology is promising as a pervasive electricity generation system for a group of wearable or implanted sensors, actuators and mobile electronics. 展开更多
关键词 human power harvesting pervasive energy electricJty generation wearable energy renewable and sustainable energy mobile electronics
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Distributed Dynamic Navigation for Sensor Networks 被引量:1
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作者 Xiaoping Wu Shili Tan +2 位作者 Tao Chen Xiaomei Yi dan dai 《Tsinghua Science and Technology》 SCIE EI CAS 2011年第6期648-656,共9页
Navigation with sensor networks has shown many advantages and great potential in many scenarios. Previous works have mainly focused on selecting the shortest path to navigate an internal user out of an emergency field... Navigation with sensor networks has shown many advantages and great potential in many scenarios. Previous works have mainly focused on selecting the shortest path to navigate an internal user out of an emergency field. However, they did not consider variations of the dangerous areas which usually occur in practical applications. This paper presents an efficient dynamic routing algorithm to successfully guide users to the destination exit. The navigation goal is looking for a safe and short path to enable the user to escape from a dangerous area as fast as possible. Without knowing the locations of the nodes, the user is guided by a sequence of sensor nodes to pass through the dangerous areas. The algorithm ensures the navigation path security by predicting the dynamic changes affecting the navigation path. The performance of this approach is evaluated using extensive simulations to validate its effectiveness. Simulations show that the approach is scalable and performs well in various settings. 展开更多
关键词 dynamic navigation sensor network EMERGENCIES expansion rate
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Tackling global electricity shortage through human power: Technical opportunities from direct or indirect utilizations of the pervasive and green human energy 被引量:1
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作者 dan dai Jing LIU 《Frontiers in Energy》 CSCD 2012年第3期210-226,共17页
With the energy and environmental problems becoming increasingly serious, human power, as a pervasive, renewable, mobile and environment friendly energy, draws more and more attention over the world. In this paper, th... With the energy and environmental problems becoming increasingly serious, human power, as a pervasive, renewable, mobile and environment friendly energy, draws more and more attention over the world. In this paper, the most basic features of human power are presented. The currently available human power harvesting theories and devices are briefly reviewed and compared. Further, direct or indirect utilization of human power in daily life, especially transportation and home appliances, such as human-powered car, watercraft, air- craft, washing machine and television etc. are summarized. Considering that the total energy from an individual is rather limited, as previously focused by most of the former works, it is conceived in this paper that an important future for large scale use of human powers lies in the efficient conversion, collection and storage of such energy from discrete people and then use it later on as desired. With the huge amount of energy gathered, the application category of human power would be significantly expended. Starting from this point, three technical ways towards efficiently utilizing human power are sketched, which are termed as human-powered grid (HPG), human-powered charger (HPC) and human-powered storage (HPS), among which, HPG is capable of collecting the electric power produced by each individual at different regions and thus can supply unique and flexible power to the customers covered in the area, without relying on the conventional electricity grid. The HPC can then charge various kinds of electrical devices instantly by a human driven generator which converts human power into electricity. Finally, the HPS can store electricity in time for later use. In this way, even for the devices requiring electricity that is strong enough, the collected human power can also serve as its reliable energy source. Meanwhile, utilization of human power becomes rather convenient and timely which guarantees its practical value. It is expected that with further research and increasing applications, human power could partially relieve the current global electricity shortage and environmental issues via its pervasive contribution. 展开更多
关键词 human energy harvesting human-powered transportation human-powered home appliances human-powered grid (HPG) human-powered charger (HPC) human-powered storage (HPS) BIOFUEL
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Harvesting biomechanical energy in the walking by shoe based on liquid metal magnetohydrodynamics 被引量:1
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作者 dan dai Jing LIU Yixin ZHOU 《Frontiers in Energy》 CSCD 2012年第2期112-121,共10页
A liquid metal magnetohydrodynamics generation system (LMMGS) was proposed and demonstrated in this paper for collecting parasitic power in shoe while walking. Unlike the conventional shoe-mounted human power harves... A liquid metal magnetohydrodynamics generation system (LMMGS) was proposed and demonstrated in this paper for collecting parasitic power in shoe while walking. Unlike the conventional shoe-mounted human power harvesters that use solid coil and gear mechanism, the proposed system employs liquid metal (Ga62In25Sn13) as energy carrier, where no moving part is requested in magnetohydrodynamics generators (MHGs). While walk- ing with the LMMGS, the foot alternately presses the two liquid metal pumps (LMPs) which are respectively placed in the front and rear of the sole. As a result, the liquid metal in the LMPs (LMP I and II) is extruded and flows through the MHGs (MHG I and II) in which electricity is produced. For a comparison, three types ofLMMGSs (LMMGS A, B and C) were built where all the parts are the same except for the LMPs. Furthermore, performances of these LMMGSs with different volume of injected liquid metal were tested respectively. Experimental results reveal that both the output voltage and power of the LMMGS increase with the volume of injected liquid metal and the size of the LMPs. In addition, a maximum output power of 80 mW is obtained by the LMMGS C with an efficiency of approximately 1.3%. Given its advantages of no side effect, light weight, small size and reliability, The LMMGS is well-suited for powering the wearable and implantable micro/nano device, such as wearable sensors, drug pumps and so on. 展开更多
关键词 human energy harvesting liquid metal wear-able magnetohydrodynamics generator parasitic power inshoe
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Enhanced thermal conductivity of epoxy composites with core-shell SiC@SiO_(2) nanowires 被引量:1
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作者 Dianyu Shen Mengjie Wang +13 位作者 Yuming Wu Zhiduo Liu Yong Cao Ting Wang Xinfeng Wu Qingtang Shi Kuan W.A.Chee Wen dai Hua Bai dan dai Jilei Lyu Nan Jiang Cheng-Te Lin Jinhong Yu 《High Voltage》 SCIE EI 2017年第3期154-160,共7页
Electronic packaging materials and thermal interface materials(TIMs)are widely used in thermal management.In this study,the epoxy composites with core-shell structure SiC@SiO_(2) nanowires(SiC@SiO_(2) NWs)as fillers c... Electronic packaging materials and thermal interface materials(TIMs)are widely used in thermal management.In this study,the epoxy composites with core-shell structure SiC@SiO_(2) nanowires(SiC@SiO_(2) NWs)as fillers could effectively enhance the thermal conductivity of epoxy composites.The unique structure of fillers results in a high thermal conductivity of epoxy composites,which is attributed to good interfacial compatibility epoxy matrix and bridging connections of SiC@SiO_(2) NWs.From neat epoxy to 2.5 wt%loading of SiC@SiO_(2) NWs,the thermal conductivity is significantly increased from 0.218 to 0.391 W m^(−1) K^(−1),increased by 79.4%.In addition,the composite with 2.5 wt%filler possess lower coefficient of thermal expansion and better thermal stability than that of neat epoxy.All these outstanding properties imply that epoxy/SiC@SiO_(2) NWs composites could be the ideal candidate for TIM. 展开更多
关键词 COMPOSITES NANOWIRES COMPOSITE
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A dense graphene monolith with poloxamer prefunctionalization enabling aqueous redispersion to obtain solubilized graphene sheets
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作者 Chen Ye Fan Zhang +13 位作者 Xue Tan Huifang Sun Wen dai Ke Yang Minghui Yang Shiyu Du dan dai Jinhong Yu Nan Jiang Weitao Su Li Fu He Li Jing Kong Cheng-Te Lin 《Chinese Chemical Letters》 SCIE CAS CSCD 2020年第9期2507-2511,共5页
The realization of good aqueous dispersibility of commercial graphene products composed of exfoliated graphene sheets is of significance for downstream applications.However,the tap density of commercial graphene powde... The realization of good aqueous dispersibility of commercial graphene products composed of exfoliated graphene sheets is of significance for downstream applications.However,the tap density of commercial graphene powder is quite low(0.03-0.1 kg/m3),meaning that 1 kg graphene powder occupies about 10-30 m3 in volume during transportation.And,the available content of commercial graphene dispersion/slurry in aqueous medium cannot exceed 5 wt%,although the density is high(≈1050 kg/m3).In this work,a graphene monolith was prepared by oven-drying of graphene sheets prefunctionalized with poloxamer surfactants.Our graphene monoliths not only have a high density(1500 kg/m^3) and high graphene content(≈10 wt%),but also a full capability to be completely redispersed(≈100%) in water by bath sonication to obtain solubilized graphene sheets,whose lateral size and thickness are unchanged compared to as-exfoliated ones.Moreover,a simple empirical method was proposed to predict the redispersion capability of graphene monoliths using different poloxamers by contact angle measurements.Our results provide a universal approach to make exfoliated graphene-based products with better downstream availability and lower transportation cost. 展开更多
关键词 Dense monolith Graphene sheets POLOXAMER Aqueous redispersion Surface functionalization
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