Human herpesviruses(HHV),including the alpha,beta,andgamma subfamilies,are enveloped viruses with broad prevalence,establishing life-time latent infections and inducing a variety of diseases[1].Among them,herpes simpl...Human herpesviruses(HHV),including the alpha,beta,andgamma subfamilies,are enveloped viruses with broad prevalence,establishing life-time latent infections and inducing a variety of diseases[1].Among them,herpes simplex virus(HSV),consists of two HSV-1 and HSV-2 variants,ubiquitouslyaffecting global populations[2].As an enveloped virus,HSV features a repertoire of glycoproteins such as glycoproteins D(gD),glycoproteins H(gH),glycoproteins L(gL),and glycoproteins B(gB),to orchestrate host cell recognition and infection[3,4].展开更多
基金supported by grants from the NationalKey Research and Development Program of China(2022YFC3400900)Chinese Postdoctoral Science Foundation(GZB20230886,2023M743998)+2 种基金Natural Science Foundationof China(82030046 to M.S.Z,82070329 and 32241028 toZ.L.)the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(2019BT02Y198)Guangdong Science and Technology Department(2020B1212030004).
文摘Human herpesviruses(HHV),including the alpha,beta,andgamma subfamilies,are enveloped viruses with broad prevalence,establishing life-time latent infections and inducing a variety of diseases[1].Among them,herpes simplex virus(HSV),consists of two HSV-1 and HSV-2 variants,ubiquitouslyaffecting global populations[2].As an enveloped virus,HSV features a repertoire of glycoproteins such as glycoproteins D(gD),glycoproteins H(gH),glycoproteins L(gL),and glycoproteins B(gB),to orchestrate host cell recognition and infection[3,4].
